PT  - JOURNAL ARTICLE
AU  - MARCELLO CECCARONI
AU  - GIOVANNI ROVIGLIONE
AU  - EMANUELA SPAGNOLO
AU  - PAOLO CASADIO
AU  - ROBERTO CLARIZIA
AU  - MICHELE PEIRETTI
AU  - FRANCESCO BRUNI
AU  - INGE PETERS
AU  - GIOVANNI ALETTI
TI  - Pelvic Dysfunctions and Quality of Life after Nerve-sparing Radical Hysterectomy: A Multicenter Comparative Study
DP  - 2012 Feb 01
TA  - Anticancer Research
PG  - 581--588
VI  - 32
IP  - 2
4099  - http://ar.iiarjournals.org/content/32/2/581.short
4100  - http://ar.iiarjournals.org/content/32/2/581.full
SO  - Anticancer Res2012 Feb 01; 32
AB  - Aim: To analyze pelvic dysfunctions, quality of life, and survival after nerve-sparing radical hysterectomy (NSRH) compared to classical radical hysterectomy (RH) for cervical cancer. Patients and Methods: All cervical cancer patients undergoing a RH or a NSRH were evaluated for pelvic dysfunctions and filled in a quality-of-life questionnaire. Results: A total of 56 women were included; 31 underwent RH (group 1) and 25 NSRH (group 2). Postoperatively, a higher number of patients had urinary incontinence (p=0.02), urinary retention (p=0.01), faecal incontinence (p=0.01) and constipation (p=0.01) in group 1 versus group 2. Patients referred a higher rate of severe sexual dysfunction after RH compared to NSRH (p=0.03). No differences were found in orgasmic frequency and sexual desire; overall quality of life evaluation was more satisfactory after NSRH. Conclusion: NSRH conferred a better clinical outcome with fewer long-term bladder, colorectal and sexual complications. Post-operative quality of life after NSRH was better, with the same overall survival as compared to RH.