RT Journal Article
SR Electronic
T1 Assessment of Sexual Function in Patients with Cancer Undergoing Radiotherapy – A Single Centre Prospective Study
JF Anticancer Research
JO Anticancer Res
FD International Institute of Anticancer Research
SP 657
OP 664
VO 32
IS 2
A1 DIMITRIOS VOMVAS
A1 GREGORIS ICONOMOU
A1 EVANTHIA SOUBASI
A1 MICHAIL LEOTSINIDIS
A1 HARALABOS P. KALOFONOS
A1 STAVROULA BERATIS
A1 DIMITRIOS KARDAMAKIS
A1 KONSTANTINOS ASSIMAKOPOULOS
YR 2012
UL http://ar.iiarjournals.org/content/32/2/657.abstract
AB Aim: The main objective was to delineate the rates and clinical course of sexual function and depression in cancer patients undergoing radiotherapy. Patients and Methods: Forty-eight male and 90 female radiotherapy-naive outpatients with breast or pelvic cancer completed the International Index of Erectile Function (IIEF) or the Female Sexual Function Index (FSFI), and the Hamilton Depression Scale (HDS) prior to (phase 1), at the end of (phase 2) and 12 months after radiotherapy (phase 3). Results: Overall, the majority of patients (93.8% of males and 80% of females) experienced intense sexual dysfunction. At presentation, males reported severe erectile dysfunction that was significantly associated with age. However, only in sexual desire was the difference between baseline and phase 3 significant. In females, an improvement was observed in all parameters of FSFI between phase 1 and 3. Females with stage III disease achieved lower scores in almost all parameters of FSFI than those with stage II. Finally, although a quarter of patients reported elevated depression scores, depression was not related to sexual function. Conclusion: A significant proportion of cancer patients experience intense levels of sexual dysfunction and depression throughout radiotherapy and the subsequent year. Pelvic radiotherapy affected sexual function to a higher degree than did breast radiotherapy.