RT Journal Article SR Electronic T1 Synchronous Double Tumor of Breast Cancer and Gastrointestinal Stromal Tumor in a Patient with Neurofibromatosis Type 1: Report of a Case JF Anticancer Research JO Anticancer Res FD International Institute of Anticancer Research SP 4481 OP 4484 VO 31 IS 12 A1 HIDEYA TAKEUCHI A1 SHOZI HIROSHIGE A1 KENKICHI HASHIMOTO A1 TETSUYA KUSUMOTO A1 YASUJI YOSHIKAWA A1 YOICHI MUTO YR 2011 UL http://ar.iiarjournals.org/content/31/12/4481.abstract AB We report a rare case of synchronous double tumor formation of breast cancer and gastrointestinal stromal tumor (GIST) in a patient with neurofibromatosis type 1(NF-1). A 76-year-old woman with a history of NF-1 who had undergone left modified mastectomy for breast cancer seven years previously was admitted to our hospital because of a right breast tumor and abdominal discomfort. Computed tomography revealed an enhanced irregular tumor in the right breast and peripheral enhanced tumors in the abdomen. The patient underwent right modified mastectomy and laparoscopic tumor resection combined with small intestine surgery. Histopathological examination revealed the presence of invasive lobular carcinoma in the right breast and GIST in the abdomen. The synchronous development of breast cancer and GIST in a patient with NF-1 is extremely rare, with this being the second case ever reported.