TY - JOUR T1 - Dissection of Unsuspicious Para-aortic Lymph Nodes Does Not Improve Prognosis of Advanced Endometrial Carcinoma with Intra- or Extra-abdominal Metastasis JF - Anticancer Research JO - Anticancer Res SP - 4513 LP - 4517 VL - 31 IS - 12 AU - YUTAKA UEDA AU - MIKA OKAZAWA AU - TAKAYUKI ENOMOTO AU - TOMOMI EGAWA-TAKATA AU - TOSHIHIRO KIMURA AU - KIYOSHI YOSHINO AU - MASAMI FUJITA AU - YUKINOBU OHTA AU - SHOJI KAMIURA AU - TADASHI KIMURA Y1 - 2011/12/01 UR - http://ar.iiarjournals.org/content/31/12/4513.abstract N2 - Background: The aim of this study was to analyze the significance of dissection of unsuspicious para-aortic lymph nodes (PAN) in patients with advanced endometrial carcinomas with intra- or extra-abdominal metastasis. Patients and Methods: We conducted a retrospective comparison of the results of PAN dissection versus non-dissection for endometrial carcinomas with macroscopic metastatic lesions beyond the uterus (without significant swelling of the regional lymph nodes, including PAN), whose lesions were completely resected. Results: Disease-free survival and overall survival did not exhibit a significant difference between the two groups. Multivariate Cox proportional hazards analysis demonstrated that PAN dissection was not an independent prognostic factor for survival. The frequency of PAN involvement at the first recurrence did not differ between the two groups. Conclusion: For advanced endometrial carcinomas with macroscopic metastatic lesions beyond the uterus, without significant swelling of regional lymph nodes, PAN dissection may be omitted without a significant adverse effect on prognosis and survival. ER -