TY - JOUR T1 - <em>MACC1</em> as a Marker for Advanced Colorectal Carcinoma JF - Anticancer Research JO - Anticancer Res SP - 2689 LP - 2692 VL - 30 IS - 7 AU - ATSUSHI SHIRAHATA AU - KAZUKI SHINMURA AU - YOUHEI KITAMURA AU - KAZUMA SAKURABA AU - KAZUAKI YOKOMIZO AU - TETSUHIRO GOTO AU - HIROKI MIZUKAMI AU - MITSUO SAITO AU - KAZUYOSHI ISHIBASHI AU - GAKU KIGAWA AU - HIROSHI NEMOTO AU - KENJI HIBI Y1 - 2010/07/01 UR - http://ar.iiarjournals.org/content/30/7/2689.abstract N2 - Background: Recently, Stein et al. identified the metastasis-associated in colon cancer 1 (MACC1) gene by genome-wide search for differentially expressed genes in human colon cancer tissues and metastases. Patients and Methods: We analyzed MACC1 expression levels in 52 colorectal cancer samples using quantitative real-time polymerase chain reaction (QRT-PCR). Results: We found that MACC1 expression showed significant correlation with peritoneal dissemination (p=0.042) and higher stage of TNM classification (p=0.007). Conclusion: These results suggest that MACC1 is more frequently expressed in advanced colorectal carcinomas. ER -