TY - JOUR T1 - Cytogenetic Effects of 18.0 and 16.5 GHz Microwave Radiation on Human Lymphocytes <em>In Vitro</em> JF - Anticancer Research JO - Anticancer Res SP - 2885 LP - 2892 VL - 29 IS - 8 AU - INGER-LISE HANSTEEN AU - LARS LĂ…GEIDE AU - KJELL OSKAR CLAUSEN AU - VERA HAUGAN AU - MARIT SVENDSEN AU - JAN GUNNAR ERIKSEN AU - ROLF SKIAKER AU - EGIL HAUGER AU - ARNT INGE VISTNES AU - ELIN H. KURE Y1 - 2009/08/01 UR - http://ar.iiarjournals.org/content/29/8/2885.abstract N2 - Background: There are few cell studies on the direct genotoxic effects of microwave radiation. In this study, cytogenetic effects of microwave radiation alone or in combination with mitomycin C (MMC) were investigated. Materials and Methods: Lymphocytes from two smoking and four non-smoking donors were exposed for 53 hours in vitro to 1.0 W/m2 continuous-wave radiation at 18.0 GHz or 10 W/m2 pulsed-wave at 16.5 GHz, alone or in combination with MMC. DNA synthesis and repair were inhibited in vitro in some cultures. Results: No synergistic effect was observed in cells exposed to combinations of microwave radiation and in vitro exposure to MMC, or to cells pre-exposed in vivo to tobacco smoke. For the 16.5 GHz pulsed exposure, a non-significant trend consisting of an increase in aberration frequencies with microwave radiation was shown for the DNA synthesis and repair inhibited cultures both with and without MMC. Conclusion: Neither 18.0 GHz continuous-wave nor 16.5 GHz pulsed-wave exposure to human lymphocytes in vitro induced statistically significant increases in chromosomal aberration frequencies. 16.5 GHz pulsed-wave exposure requires further documentation before a true negative conclusion can be drawn. ER -