Table of Contents

Clinical Studies

• Open Access

  A Landscape of Immunogenomics Assessments for Endemic Burkitt Lymphoma: Relevance to Outcomes

  TAHA I. HUDA, RAHUL JAIN, TUSHAR SINGH and GEORGE BLANCK

  Anticancer Research June 2026, 46 (6) 3231-3242; DOI: https://doi.org/10.21873/anticanres.18193
• Open Access

  Real-world Clinical Outcomes of Ivermectin and Mebendazole in Cancer Patients: Results from a Prospective Observational Cohort

  NICOLAS HULSCHER, KELLY VICTORY, JAMES A. THORP, DREW PINSKY, ALEJANDRO DIAZ-VILLALOBOS, PETER GILLOOLY, FOSTER COULSON, MELISSA ANNAZONE, CHLOE RADESI, JESSICA BROOKS, PETER A. McCULLOUGH and HARVEY RISCH

  Anticancer Research June 2026, 46 (6) 3243-3255; DOI: https://doi.org/10.21873/anticanres.18194
• Open Access

  Prior Chlamydia trachomatis Infection and the Risk of Epithelial Ovarian Cancer and Borderline Ovarian Tumors

  HILLA TÖRMÄNEN, HEIKKI HUHTAMÄKI, TIINA HOLSTER, ULLA PUISTOLA, MIRJA PUOLAKKAINEN and ELINA URPILAINEN

  Anticancer Research June 2026, 46 (6) 3257-3265; DOI: https://doi.org/10.21873/anticanres.18195
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  Circulating Tumor DNA Methylation Level Is a More Accurate Prognostic Biomarker in Colon Cancer

  YUTA MURAI, KIICHI SUGIMOTO, TAKAHIRO IRIE, TAKASHI FUJISAKI, ATSUHIKO HAMADA, YUJI ANDO, SAKI KOCHI, MIYUKI TOAKE, YUKI NAKAGAWA, HIROMITSU TAKAHASHI, HIROTAKA MOMOSE, YUKI TSUCHIYA, RYOICHI TSUKAMOTO, HISASHI RO, KUMPEI HONJO, MAKOTO TAKAHASHI and ROBERT M. HOFFMAN

  Anticancer Research June 2026, 46 (6) 3267-3280; DOI: https://doi.org/10.21873/anticanres.18196
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  Genomic Profiling of Cancerous Areas, Dysplasia, and Background Mucosa in Ulcerative Colitis-associated Colorectal Cancer

  KAORUKO FUNAKOSHI, KAZUHITO SASAKI, KEISUKE HATA, HIROAKI NOZAWA, KOJI MURONO, SHIGENOBU EMOTO, YUICHIRO YOKOYAMA, TAKAHIDE SHINAGAWA, SHINJI KOHSAKA, AYA SHINOZAKI-USHIKU, TETSUO USHIKU, KATSUTOSHI ODA, KENJI TATSUNO, KIYOSHI MIYAGAWA, HIROYUKI ABURATANI, HIROYUKI MANO and SOICHIRO ISHIHARA

  Anticancer Research June 2026, 46 (6) 3281-3291; DOI: https://doi.org/10.21873/anticanres.18197
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  Development of a Prognostic Model for Patients Aged ≤65 Years With Metastatic Renal Cell Carcinoma

  YUYA OISHI, YUTO MATSUSHITA, SHINYA WATANABE, KYOHEI WATANABE, HIROMITSU WATANABE, KEITA TAMURA, DAISUKE MOTOYAMA, TAKAFUMI YANAGISAWA, KEIICHIRO MORI, SEITETSU SUGIYAMA, KENSUKE BEKKU, SHINGO TOYODA, TAKUHISA NUKAYA, RYOICHI MAENOSONO, KAZUMASA KOMURA, MOTOO ARAKI, KAZUTOSHI FUJITA, KIYOSHI TAKAHARA, HARUHITO AZUMA, TERUO INAMOTO and JK-FOOT STUDY GROUP

  Anticancer Research June 2026, 46 (6) 3293-3302; DOI: https://doi.org/10.21873/anticanres.18198
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  The Prognostic Impact of Perioperative Inflammatory Status in Elderly Patients With Gastric Cancer

  TAKAHIRO TOYOKAWA, MAMI YOSHII, TAKEMI ISHIDATE, HIRONARI MIYAMOTO, KENJI KURODA, YUICHIRO MIKI, TATSURO TAMURA, SHIGERU LEE, MASAKAZU YASHIRO and KIYOSHI MAEDA

  Anticancer Research June 2026, 46 (6) 3303-3315; DOI: https://doi.org/10.21873/anticanres.18199
• Open Access

  Prognostic and Neurological Outcomes Following Surgery for Spinal NF2-Associated Ependymomas With Cysts

  FLORIAN GRIMM, TIM M. MÜLHÖFER, ULRIKE ERNEMANN, MARTIN U. SCHUHMANN, JOHANNES A. KOEPPEN, MARCOS TATAGIBA, VICTOR-FELIX MAUTNER and ISABEL GUGEL

  Anticancer Research June 2026, 46 (6) 3317-3332; DOI: https://doi.org/10.21873/anticanres.18200
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  Real-world Patterns and Trends of Intravesical Chemotherapy for Non-muscle Invasive Bladder Cancer: Insights from a Large Prospective German Cohort

  TOBIAS KLATTE, SEBASTIAN L. HOFBAUER, JÜRGEN EBERT and THORSTEN H. ECKE

  Anticancer Research June 2026, 46 (6) 3333-3342; DOI: https://doi.org/10.21873/anticanres.18201
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  Pembrolizumab and Quality of Life in Recurrent or Metastatic Head and Neck Cancer

  KOUSUKE HIHARA, ISAKU OKAMOTO, KUNIHIKO TOKASHIKI, YURI UEDA, KENJI HANYU and KIYOAKI TSUKAHARA

  Anticancer Research June 2026, 46 (6) 3343-3350; DOI: https://doi.org/10.21873/anticanres.18202
• Open Access

  Preoperative Serum Total Cholesterol Predicts Adjuvant Chemotherapy Completion After Pancreaticoduodenectomy for Pancreatic Cancer

  KOSUKE HATTA, SADAAKI NISHIMURA, RYOTA TANAKA, HIROJI SHINKAWA, KOHEI NISHIO, MASAHIKO KINOSHITA, JUN TAUCHI, SHIGEAKI KURIHARA and TAKEAKI ISHIZAWA

  Anticancer Research June 2026, 46 (6) 3351-3361; DOI: https://doi.org/10.21873/anticanres.18203
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  Unfavorable Outcomes of T3N0 Remnant Gastric Cancer After Distal Gastrectomy

  SHOTA SHIMIZU, TOMOYUKI MATSUNAGA, HIROAKI SAITO, TOMOHIRO OSAKI, KENJI FUKUDA, YOJI FUKUMOTO, SADAMU TAKAHASHI, KENJIRO TANIGUCHI, AKEMI IWAMOTO, HIROHIKO KURODA, KUNIYUKI KATANO, YUJI SHISHIDO, KOZO MIYATANI, TERUHISA SAKAMOTO and YOSHIYUKI FUJIWARA

  Anticancer Research June 2026, 46 (6) 3363-3371; DOI: https://doi.org/10.21873/anticanres.18204
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  The Association Between Longitudinal Changes in TRACP-5b and Bone Metastasis Progression During Osimertinib Therapy

  KEISUKE IKEGAMI, REIKO ANDO MAKIHARA, YUKI SHINNO, AKIKO TATEISHI, TOMONORI MIZUTANI, YUSUKE OKUMA, TATSUYA YOSHIDA, HIDEHITO HORINOUCHI, NOBORU YAMAMOTO, HIRONOBU HASHIMOTO, SATOKO HORI and YASUSHI GOTO

  Anticancer Research June 2026, 46 (6) 3373-3381; DOI: https://doi.org/10.21873/anticanres.18205
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  Predictive Role of PSA Kinetics in Oncological Outcomes of Metastatic Castration-sensitive Prostate Cancer

  YUTAKA YAMAMOTO, NAOKI MATSUMURA, SAIZOU FUJIMOTO, TSUYOSHI MORITA, TAIZO UCHIMOTO, WATARU FUKUOKAYA, MASANOBU SARUTA, SEITETSU SUGIYAMA, KEITA TAMURA, HARUHITO AZUMA, TAKAHIRO KIMURA, KIYOSHI TAKAHARA, KAZUMASA KOMURA, TERUO INAMOTO and KAZUTOSHI FUJITA

  Anticancer Research June 2026, 46 (6) 3383-3393; DOI: https://doi.org/10.21873/anticanres.18206
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  Antiemetic Efficacy of Aprepitant in Cisplatin–Gemcitabine Therapy for Biliary Tract Cancer: A Multicenter Study

  KENGO UMEHARA, YOSHITAKA SAITO, DAISUKE HIRATE, AYA KOOKA, RYO FUJIBAYASHI, SHUICHI TAKASAKI, TAKASHI SHIMOGUCHIYA, AYUKO KUSAKABE, TOMOAKI HATAKEYAMA, YUKI HASEGAWA, ATSUYA SHIMIZU, AKIHIDE OTA, KENTA MAEDA, TAIKI WATANABE, SHINYA TAKADA, TAKAKO OBARA, HIROYUKI NAGASHIMA, TAMOTSU SAGAWA, KOSHI FUJIKAWA and HIROYUKI KAWAGUCHI

  Anticancer Research June 2026, 46 (6) 3395-3406; DOI: https://doi.org/10.21873/anticanres.18207
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  Pretreatment Tumor Growth Rate and Clinical Outcomes in Advanced Non–small Cell Lung Cancer

  YUTAKA TAKAHARA, RYUDAI ABE, SUMITO NAGAE, TAKUYA TANAKA, YOKO ISHIGE, IKUYO SHIONOYA, KOUICHI YAMAMURA, MASAFUMI NOJIRI and MASAHARU IGUCHI

  Anticancer Research June 2026, 46 (6) 3407-3415; DOI: https://doi.org/10.21873/anticanres.18208
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  Dual Modality and Site-differentiated Sentinel Node Mapping in Vulvar Cancer

  BERND MORGENSTERN, MATTHIAS SCHMIDT and FABINSHY THANGARAJAH

  Anticancer Research June 2026, 46 (6) 3417-3423; DOI: https://doi.org/10.21873/anticanres.18209
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  Standard Clinical Characteristics Fail to Predict Mild Chemotherapy-induced Peripheral Neuropathy in Breast Cancer Patients

  DIRK RADES, MARIA K. STREUBEL, CHRISTIAN STAACKMANN, LAURA DOEHRING, ACHIM RODY, MARIA J. NORMANN HAVERBERG and MARTIN BALLEGAARD

  Anticancer Research June 2026, 46 (6) 3425-3430; DOI: https://doi.org/10.21873/anticanres.18210
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  Clinical Outcomes in Advanced Gastric Cancer Among Patients Aged ≥80 Years Treated With Chemotherapy

  TAKUMI ITO, KYOKO KATO, MASAHIRO YAGUCHI, SEIRA OWAKI, MARIKO SATO, RIKU INO, KAZUHIRO SHIRAISHI, KEIJI SUGIYAMA, YASUO UNO, MASASHI HATTORI, MASAYA SUENAGA, MUTSUMI MURAYAMA, MASAAKI SHIMADA, YASUHIRO KODERA and CHIYOE KITAGAWA

  Anticancer Research June 2026, 46 (6) 3431-3440; DOI: https://doi.org/10.21873/anticanres.18211
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  Clinical Outcomes and Failure Patterns After Postoperative IMRT for Olfactory Neuroblastoma: Late Cervical Nodal Relapse

  AKARI NISHIDA, RYOTA NAKASHIMA, SHINYA HIRAOKA, AYA NAKAJIMA, MICHIO YOSHIMURA, YUJI KITADA, MAMI MATSUNAGA, MASAHIRO KIKUCHI, TAKAYUKI NAKAGAWA, YO KISHIMOTO and TAKASHI MIZOWAKI

  Anticancer Research June 2026, 46 (6) 3441-3451; DOI: https://doi.org/10.21873/anticanres.18212
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  Three-factor Clinical Score for First-line Nivolumab Plus Ipilimumab in Metastatic Renal Cell Carcinoma

  MASAAKI YANISHI, TAKAHIRO NAKAMOTO, TAKASHI YOSHIDA, TAKAO MISHIMA and HIDEFUMI KINOSHITA

  Anticancer Research June 2026, 46 (6) 3453-3459; DOI: https://doi.org/10.21873/anticanres.18213
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  Clinical Features and Prognostic Significance of Pulmonary Metastases in Metastatic Hormone-sensitive Prostate Cancer

  YASUTAKA YAMADA, MARIKA MATSUMOTO, MAI IKEHARA, TAKUYA TSUJINO, KODAI SATO, SHINPEI SAITO, YUKI YOSHIKAWA, RYOICHI MAENOSONO, SATOSHI YAMAMOTO, TAKAYUKI ARAI, HIROAKI SATO, KOSUKE HIGUCHI, AKINORI TAKEI, MANATO KANESAKA, KEISUKE ANDO, SANGJON PAE, SANJI KANAOKA, NOBUSHIGE TAKESHITA, KEI YONEDA, DAICHI HINO, TAKAAKI TAMURA, TOMOKAZU SAZUKA, YUSUKE IMAMURA, KAZUO MIKAMI, KAZUYOSHI NAKAMURA, SATOSHI FUKASAWA, AKIRA KUROZUMI, YUKIO NAYA, MAKI NAGATA, ATSUSHI KOMARU, TOYOFUSA TOBE, NORIYUKI SUZUKI, HARUHITO AZUMA and SHINICHI SAKAMOTO

  Anticancer Research June 2026, 46 (6) 3461-3472; DOI: https://doi.org/10.21873/anticanres.18214
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  Clinical Outcomes and Prognostic Factors in Patients With Pelvic Sarcomas

  MASANORI KAWANO, YUTA KUBOTA, ICHIRO ITONAGA, NOBUHIRO KAKU and KAZUHIRO TANAKA

  Anticancer Research June 2026, 46 (6) 3473-3481; DOI: https://doi.org/10.21873/anticanres.18215
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  Comparison of RATS Lobectomy and VATS Lobectomy for Early-stage Non-small Cell Lung Cancer

  TOMOYOSHI TAKENAKA, TAKAYUKI TOKUNAGA, FUMIHIKO KINOSHITA, NAOYA IWAMOTO, TAICHI MATSUBARA, KAZUKI TAKADA and TOMOHARU YOSHIZUMI

  Anticancer Research June 2026, 46 (6) 3483-3491; DOI: https://doi.org/10.21873/anticanres.18216
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  Effectiveness of Chemotherapy With/Without Radiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma: A Population-based Target Trial Emulation Study

  CHEN-YUAN LIN, YU-SEN LIN, HSIN-YUAN FANG, CHUN-CHIEH WANG, JI-AN LIANG, CHIA-CHIN LI and CHUN-RU CHIEN

  Anticancer Research June 2026, 46 (6) 3493-3508; DOI: https://doi.org/10.21873/anticanres.18217