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Research ArticleClinical Studies

Pregabalin for Opioid-resistant Neuropathic Pain in Bone Metastases

KIYOHIRO SAKAI, YASUKO IKEDA-SAKAI and HIROMICHI MATSUOKA
Anticancer Research May 2026, 46 (5) 2663-2670; DOI: https://doi.org/10.21873/anticanres.18146
KIYOHIRO SAKAI
1Department of Palliative Care, Kurashiki Central Hospital, Okayama, Japan;
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  • For correspondence: ks17452{at}kchnet.or.jp
YASUKO IKEDA-SAKAI
2Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan;
3Department of Neurology, Kyoto University Hospital, Kyoto, Japan;
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HIROMICHI MATSUOKA
4Department of Palliative and Supportive Care Development Division, National Cancer Center Japan, Tokyo, Japan
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Article Information

vol. 46 no. 5 2663-2670
DOI 
https://doi.org/10.21873/anticanres.18146
PMID 
42049348

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received February 18, 2026
  • Revision received March 25, 2026
  • Accepted March 27, 2026
  • Published online April 28, 2026.

Copyright & Usage 
Copyright © 2026 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. KIYOHIRO SAKAI1⇑,
  2. YASUKO IKEDA-SAKAI2,3 and
  3. HIROMICHI MATSUOKA4
  1. 1Department of Palliative Care, Kurashiki Central Hospital, Okayama, Japan;
  2. 2Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan;
  3. 3Department of Neurology, Kyoto University Hospital, Kyoto, Japan;
  4. 4Department of Palliative and Supportive Care Development Division, National Cancer Center Japan, Tokyo, Japan
  1. Kiyohiro Sakai, MD, PhD, Department of Palliative Care, Kurashiki Central Hospital, 1-1-1 Miwa Kurashiki, Okayama 710-8602, Japan. Tel: +81 864220210, e-mail: ks17452{at}kchnet.or.jp
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Anticancer Research: 46 (5)
Anticancer Research
Vol. 46, Issue 5
May 2026
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Pregabalin for Opioid-resistant Neuropathic Pain in Bone Metastases
KIYOHIRO SAKAI, YASUKO IKEDA-SAKAI, HIROMICHI MATSUOKA
Anticancer Research May 2026, 46 (5) 2663-2670; DOI: 10.21873/anticanres.18146

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Pregabalin for Opioid-resistant Neuropathic Pain in Bone Metastases
KIYOHIRO SAKAI, YASUKO IKEDA-SAKAI, HIROMICHI MATSUOKA
Anticancer Research May 2026, 46 (5) 2663-2670; DOI: 10.21873/anticanres.18146
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Keywords

  • Pregabalin
  • bone metastases
  • opioid-resistant pain
  • neuropathic pain
  • cancer
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