Ubiquitin Ligase RNF149 Promotes Head and Neck Cancer Growth via Downregulation of CDKN2C

YU-HSUAN HUNG; MIN-HONG WANG; LI-TZONG CHEN; MEI-REN PAN; HUI-CHING WANG; SIN-HUA MOI; CHI-WEN LUO

doi:10.21873/anticanres.18137

Research ArticleExperimental Studies

Ubiquitin Ligase RNF149 Promotes Head and Neck Cancer Growth via Downregulation of CDKN2C

YU-HSUAN HUNG, MIN-HONG WANG, LI-TZONG CHEN, MEI-REN PAN, HUI-CHING WANG, SIN-HUA MOI and CHI-WEN LUO

Anticancer Research May 2026, 46 (5) 2551-2564; DOI: https://doi.org/10.21873/anticanres.18137

YU-HSUAN HUNG

1Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C.;

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For correspondence: yhhung2021{at}gmail.com 1120413{at}kmuh.org.tw

MIN-HONG WANG

2Division of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C.;

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LI-TZONG CHEN

3Division of Gastroenterology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C.;

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MEI-REN PAN

4Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C.;

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HUI-CHING WANG

2Division of Hematology and Oncology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C.;

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SIN-HUA MOI

4Graduate Institute of Clinical Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C.;

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CHI-WEN LUO

5Division of Breast Oncology and Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C.

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Ubiquitin Ligase RNF149 Promotes Head and Neck Cancer Growth via Downregulation of CDKN2C

YU-HSUAN HUNG, MIN-HONG WANG, LI-TZONG CHEN, MEI-REN PAN, HUI-CHING WANG, SIN-HUA MOI, CHI-WEN LUO

Anticancer Research May 2026, 46 (5) 2551-2564; DOI: 10.21873/anticanres.18137

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Ubiquitin Ligase RNF149 Promotes Head and Neck Cancer Growth via Downregulation of CDKN2C

YU-HSUAN HUNG, MIN-HONG WANG, LI-TZONG CHEN, MEI-REN PAN, HUI-CHING WANG, SIN-HUA MOI, CHI-WEN LUO

Anticancer Research May 2026, 46 (5) 2551-2564; DOI: 10.21873/anticanres.18137

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Keywords

RNF149
head and neck squamous cell carcinoma
HNSC
CDKN2C
CGP60474
proximity ligation assay
PLA

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