6-O-Carboxypropyl-α-Tocotrienol Enhances the Anticancer Effects of Bortezomib Without Suppressing NRF1 and NRF3 in Colorectal Cancer Cells

KYOTA ISHII; TOMOHIRO YANO

doi:10.21873/anticanres.18124

Research ArticleExperimental Studies

6-O-Carboxypropyl-α-Tocotrienol Enhances the Anticancer Effects of Bortezomib Without Suppressing NRF1 and NRF3 in Colorectal Cancer Cells

KYOTA ISHII and TOMOHIRO YANO

Anticancer Research May 2026, 46 (5) 2375-2386; DOI: https://doi.org/10.21873/anticanres.18124

KYOTA ISHII

1Laboratory of Molecular Bromacology, Graduate School of Health and Sports Sciences, Toyo University, Tokyo, Japan;

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For correspondence: s4h202300016{at}toyo.jp

TOMOHIRO YANO

1Laboratory of Molecular Bromacology, Graduate School of Health and Sports Sciences, Toyo University, Tokyo, Japan;

2Research Institute of Life Innovation, Toyo University, Tokyo, Japan

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Anticancer Research

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May 2026

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6-O-Carboxypropyl-α-Tocotrienol Enhances the Anticancer Effects of Bortezomib Without Suppressing NRF1 and NRF3 in Colorectal Cancer Cells

KYOTA ISHII, TOMOHIRO YANO

Anticancer Research May 2026, 46 (5) 2375-2386; DOI: 10.21873/anticanres.18124

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6-O-Carboxypropyl-α-Tocotrienol Enhances the Anticancer Effects of Bortezomib Without Suppressing NRF1 and NRF3 in Colorectal Cancer Cells

KYOTA ISHII, TOMOHIRO YANO

Anticancer Research May 2026, 46 (5) 2375-2386; DOI: 10.21873/anticanres.18124

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Keywords

Bortezomib
proteasome inhibitor
colorectal cancer
NRF1
NRF3

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