Table of Contents

Clinical Studies

• Open Access

  PRDX4 Potentially Serves as an Independent Marker for Early Recurrence of Oral Squamous Cell Carcinoma

  TAIJIRO HASHIMOTO, TAKERU OYAMA, YANGXIAN ZHANG, YUKINOBU ITO, JIA HAN, YAO LIU, MITSUAKI YOSHIDA, AKIHIRO SHIOYA, MASASHI OKURO, MORIMASA KITAMURA and SOHSUKE YAMADA

  Anticancer Research May 2026, 46 (5) 2583-2597; DOI: https://doi.org/10.21873/anticanres.18139
• Open Access

  Real-world Delivery and Outcomes of Intravesical BCG for Non–muscle-invasive Bladder Cancer

  NOBUKI FURUBAYASHI, JIRO TSUJITA, AZUSA TAKAYAMA, YUTA SHIRAISHI, MOTONOBU NAKAMURA and TAKAHITO NEGISHI

  Anticancer Research May 2026, 46 (5) 2599-2608; DOI: https://doi.org/10.21873/anticanres.18140
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  Identification of Risk Factors for the Local Recurrence of Hepatocellular Carcinoma Post-radiofrequency Ablation

  KOSUKE TANAKA, AKIFUMI KUWANO, MASAYOSHI YADA, HIDEO SUZUKI and KENTA MOTOMURA

  Anticancer Research May 2026, 46 (5) 2609-2618; DOI: https://doi.org/10.21873/anticanres.18141
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  Robotic-assisted Distal Pancreatectomy Is Associated With Significant Reduction of Morphine Consumption for the Treatment of Acute Postoperative Pain

  AMELIE F. KRUSE, ANDREAS ANDREOU, HALUK MORGUL, MIRA KUELLMAR, SHADI KATOU, MAZEN A. JURATLI, CARSTEN SZARDENINGS, ANDREAS PASCHER, BENJAMIN STRUECKER and JENS P. HOELZEN

  Anticancer Research May 2026, 46 (5) 2619-2630; DOI: https://doi.org/10.21873/anticanres.18142
• Open Access

  Evaluation of Quality Metrics for Dose Assessment in Field Overlap Regions of VMAT-Based Craniospinal Axis Irradiation

  CHRISTIAN ZIEMANN, FLORIAN CREMERS, LISA MUENDLEIN, CLAUDIA HOFFMANN, DIRK RADES and ANASTASSIA LÖSER

  Anticancer Research May 2026, 46 (5) 2631-2642; DOI: https://doi.org/10.21873/anticanres.18143
• Open Access

  Early Progressive Disease Predicts Poor Outcomes of Second-line VEGFR Tyrosine Kinase Inhibitor Therapy After First-line Nivolumab Plus Ipilimumab in Advanced Renal Cell Carcinoma

  NOBUKI FURUBAYASHI, JIRO TSUJITA, AZUSA TAKAYAMA, YUTA SHIRAISHI, MOTONOBU NAKAMURA and TAKAHITO NEGISHI

  Anticancer Research May 2026, 46 (5) 2643-2651; DOI: https://doi.org/10.21873/anticanres.18144
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  Prognostic Difference According to the Site of Origin (Major vs. Minor) of Salivary Gland Carcinoma

  MIOKO MATSUO, YUTARO KIDA, KAZUKI HASHIMOTO, RYUNOSUKE KOGO, NORITAKA KOMUNE, MASANOBU SATO, YUSUKE MIYAMOTO, TOMOMI MANAKO, SHOGO MASUDA and TAKASHI NAKAGAWA

  Anticancer Research May 2026, 46 (5) 2653-2661; DOI: https://doi.org/10.21873/anticanres.18145
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  Pregabalin for Opioid-resistant Neuropathic Pain in Bone Metastases

  KIYOHIRO SAKAI, YASUKO IKEDA-SAKAI and HIROMICHI MATSUOKA

  Anticancer Research May 2026, 46 (5) 2663-2670; DOI: https://doi.org/10.21873/anticanres.18146
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  Diameter of IPDA Is Associated With Maintenance of Hepatic Arterial Blood Flow in DP-CAR

  RYO MURANUSHI, ISAKU YOSHIOKA, NANA KIMURA, MINA FUKASAWA, AYANO SAKAI, YOSHIHIRO SHIRAI, TORU WATANABE, KATSUHISA HIRANO, KAZUTO SHIBUYA and TSUTOMU FUJII

  Anticancer Research May 2026, 46 (5) 2671-2681; DOI: https://doi.org/10.21873/anticanres.18147
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  Macroscopic Tumor Color as a Surrogate for Biological Diversity in Clear Cell Renal Cell Carcinoma

  NOZOMI TSUJIO, CHISATO OHE, MASANORI SHIOHARA, NAO YUKIMATSU, TAKESHI YAMASAKI, MASAHIRO KATO, RENA UNO, JUNJI UCHIDA and KENICHI KOHASHI

  Anticancer Research May 2026, 46 (5) 2683-2692; DOI: https://doi.org/10.21873/anticanres.18148
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  Effect of Increased Image Matrix on Lung Nodule Volumetry in Chest CT: A Phantom Study

  MIKE GULDIMANN, MONA EL-GEDAILY, BASTIAN CIMANDER, DANA BELDE, ANDRÉ EULER, JAKOB HEIMER, RAHEL A. KUBIK-HUCH and TILO NIEMANN

  Anticancer Research May 2026, 46 (5) 2693-2702; DOI: https://doi.org/10.21873/anticanres.18149
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  Prognostic Significance of the Lymph Node Ratio in Obstructive Colorectal Cancer: A Retrospective Multicenter Study

  TOSHIO SHIRAISHI, TETSURO TOMINAGA, TAKASHI NONAKA, YUMA TAKAMURA, HIROKI KATAYAMA, SHINTARO HASHIMOTO, MARIKO YAMASHITA, KEISUKE NODA, KAZUKI MOTOYAMA, RIKA ONO, MAKOTO HISANAGA, AKIKO FUKUDA, MASAAKI MORIYAMA, FUMITAKE UCHIDA, MASAKI KUNIZAKI and KEITARO MATSUMOTO

  Anticancer Research May 2026, 46 (5) 2703-2711; DOI: https://doi.org/10.21873/anticanres.18150
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  Potential of Inflammatory and Nutritional Markers and Clinicopathological Factors for Prognostic Prediction in Osteosarcoma

  KAZUHIKO HASHIMOTO, SHUNIJI NISHIMURA and KOJI GOTO

  Anticancer Research May 2026, 46 (5) 2713-2723; DOI: https://doi.org/10.21873/anticanres.18151
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  Timing and Risk Factors for Hyperglycemia Associated With Anamorelin Administration

  YOSHIHIRO AMAKAWA, KAZUO KOBAYASHI, YUMA NONOMIYA, HISANORI SHIMIZU, KAZUYOSHI KAWAKAMI, TAKASHI YOKOKAWA, NAOKI SASAHIRA, MASATO OZAKA, TSUYOSHI TAKEDA, KENSEI YAMAGUCHI, DAISUKE TAKAHARI, MAKOTO NISHIO, RYO ARIYASU, TORU KITAZAWA and MASAKAZU YAMAGUCHI

  Anticancer Research May 2026, 46 (5) 2725-2733; DOI: https://doi.org/10.21873/anticanres.18152
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  Laparotomy After Total Pelvic Exenteration: Current Status and Techniques for Ileal Conduit Preservation

  KOJI KOMORI, TAKASHI KINOSHITA, AKIRA OUCHI, TAKAYOSHI KISHIDA, TAKUYA KITAHARA, HIRONOBU YASUOKA, SHUICHIRO ANDO, SEIJI ITO, KAZUNARI MISAWA, YUICHI ITO, JUNPEI YAMAGUCHI, EIJI HIGAKI, TOMONARI ASANO, MASATAKA OKUNO, TAKAHIRO HOSOI, KOSUKE INADA, KIYOSHI NARITA, HIDENORI OJIO, MASASHI NEGITA, KOTARO OZAKI and TETSUYA ABE

  Anticancer Research May 2026, 46 (5) 2735-2741; DOI: https://doi.org/10.21873/anticanres.18153
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  Recurrence Risk Stratification in Clear Cell Renal Cell Carcinoma Using TNM 2017 and WHO/ISUP Grade

  KOSUKE HAMADA, TAKESHI YAMASAKI, CHISATO OHE, NOZOMI TSUJIO, SHOMA YAMAMOTO, TAISUKE MATSUE, NAO YUKIMATSU, TAIYO OTOSHI, MINORU KATO, KATSUYUKI KURATSUKURI, MASANORI SHIOHARA, KENICHI KOHASHI and JUNJI UCHIDA

  Anticancer Research May 2026, 46 (5) 2743-2751; DOI: https://doi.org/10.21873/anticanres.18154
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  Prognostic Impact of the Geriatric Nutritional Risk Index in Elderly Patients With Colorectal Cancer

  YASUNOBU KOBAYASHI, YASUHIRO TAKANO, ANNA FUKUSHIMA, TERUYUKI TAKISHIMA, TEPPEI KAMADA, YUTA IMAIZUMI, SHUNJIN RYU, YASUHIRO TAKEDA, HIRONORI KANNO, NOBUYOSHI HANYU and KEN ETO

  Anticancer Research May 2026, 46 (5) 2753-2762; DOI: https://doi.org/10.21873/anticanres.18155
• Open Access

  A Reminder App for Optimizing Bladder Filling During Radiotherapy for Prostate Cancer: A Pre-study in Healthy Volunteers

  DIRK RADES, CARLOS A. NARVAEZ-WOLF, INGA C. ZWAAN, CHRISTINE VESTERGÅRD-MADSEN, CHARLOTTE KRISTIANSEN and JAN-DIRK KÜTER

  Anticancer Research May 2026, 46 (5) 2763-2770; DOI: https://doi.org/10.21873/anticanres.18156
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  Practical Implementation and Validation of Geriatric Assessment in Older Adults With Esophageal Cancer

  TETSURO KAWAZOE, TOMONORI NAKANOKO, TOMOYA HARIMA, KEITA NATSUGOE, YUKI SHIN, SHO NAMBARA, YASUO TSUDA, KOJI ANDO, EIJI OKI and TOMOHARU YOSHIZUMI

  Anticancer Research May 2026, 46 (5) 2771-2779; DOI: https://doi.org/10.21873/anticanres.18157
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  Life-threatening Pneumonitis Induced by Osimertinib Monotherapy as a First-line Treatment for Epidermal Growth Factor Receptor Mutation-positive Non-small-cell Lung Cancer: A Retrospective Case-series Study

  TAKASHI NOJIRI, AKIISA OMURA, HIROSHI NISHIMURA, HIROSHI UDA, MICHIHITO KATAYAMA, KIYOTSUGU IEDE, YUKI TAKEYASU, UTAE KATSUSHIMA, HIROSHI OKADA and MASAHIKO HIGASHIYAMA

  Anticancer Research May 2026, 46 (5) 2781-2788; DOI: https://doi.org/10.21873/anticanres.18158
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  Cancer Cachexia Predicts Benefit of Immunotherapy Plus Chemotherapy in EGFR-mutant NSCLC After TKI Resistance

  HARUKA NAKATANI, HAYATO KAWACHI, TADAAKI YAMADA, NAOKI FURUYA, HISASHI TANAKA, AKIHIRO YOSHIMURA, TOMOHIRO OBA, MAKOTO HIBINO, TAKAHITO FUKUDA, YASUHIRO GOTO, AKIRA NAKAO, SHINSUKE OGUSU, YUTA OKAZAKI, TAISHI HARADA, TAKAYO OTA, KEN MASUBUCHI, KOJI MIKAMI, TAE HATA, KENJI MORIMOTO and KOICHI TAKAYAMA

  Anticancer Research May 2026, 46 (5) 2789-2806; DOI: https://doi.org/10.21873/anticanres.18159
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  Preoperative Cachexia Index Predicts Overall Survival Following Curative Resection for Remnant Gastric Cancer

  TOMOYUKI MATSUNAGA, JUNPEI ORIHARA, TOMOHIRO TAKAHASHI, SHOTA SHIMIZU, YUJI SHISHIDO, KOZO MIYATANI, MANABU YAMAMOTO, SYUICHI TAKANO, NARUO TOKUYASU, TERUHISA SAKAMOTO, HIROOMI OKUYAMA and YOSHIYUKI FUJIWARA

  Anticancer Research May 2026, 46 (5) 2807-2815; DOI: https://doi.org/10.21873/anticanres.18160
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  Postoperative Changes in Nutritional Status and their Impact on Post-recurrence Prognosis After Pancreatoduodenectomy in Patients With Biliary Tract Carcinoma: An Age-stratified Analysis

  WATARU IZUMO, RYO SAITO, HIDETAKE AMEMIYA, SUGURU MARUYAMA, KOICHI TAKIGUCHI, KATSUTOSHI SHODA, KENSUKE SHIRAISHI, SHINJI FURUYA, YOSHIHIKO KAWAGUCHI, HIROMICHI KAWAIDA and DAISUKE ICHIKAWA

  Anticancer Research May 2026, 46 (5) 2817-2828; DOI: https://doi.org/10.21873/anticanres.18161