Effectiveness of Pembrolizumab Monotherapy for Older Adults With Head and Neck Carcinoma by CPS Status

YURI UEDA; TAKURO OKADA; ISAKU OKAMOTO; CHIHIRO FUSHIMI; TAKASHI MATSUKI; HIDEAKI TAKAHASHI; HIROKI SATO; TAKAHITO KONDO; KUNHIKO TOKASHIKI; KENJI HANYU; TAKUMA KISHIDA; TATSUYA ITO; GAI YAMASHITA; TATSUO MASUBUCHI; YUICHIRO TADA; GO OMURA; TAKU YAMASHITA; NOBUHIKO ORIDATE; KIYOAKI TSUKAHARA

doi:10.21873/anticanres.18059

Research ArticleClinical Studies

Effectiveness of Pembrolizumab Monotherapy for Older Adults With Head and Neck Carcinoma by CPS Status

YURI UEDA, TAKURO OKADA, ISAKU OKAMOTO, CHIHIRO FUSHIMI, TAKASHI MATSUKI, HIDEAKI TAKAHASHI, HIROKI SATO, TAKAHITO KONDO, KUNHIKO TOKASHIKI, KENJI HANYU, TAKUMA KISHIDA, TATSUYA ITO, GAI YAMASHITA, TATSUO MASUBUCHI, YUICHIRO TADA, GO OMURA, TAKU YAMASHITA, NOBUHIKO ORIDATE and KIYOAKI TSUKAHARA

Anticancer Research March 2026, 46 (3) 1639-1650; DOI: https://doi.org/10.21873/anticanres.18059

YURI UEDA

1Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan;

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For correspondence: yuriueda{at}tokyo-med.ac.jp

TAKURO OKADA

1Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan;

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ISAKU OKAMOTO

1Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan;

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CHIHIRO FUSHIMI

2Department of Head and Neck Oncology, National Cancer Center Hospital, Tokyo, Japan;

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TAKASHI MATSUKI

3Department of Otorhinolaryngology, Head and Neck Surgery, Kitasato University School of Medicine, Kanagawa, Japan;

4Department of Head and Neck Surgery, Kanagawa Cancer Center, Kanagawa, Japan;

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HIDEAKI TAKAHASHI

2Department of Head and Neck Oncology, National Cancer Center Hospital, Tokyo, Japan;

5Department of Otorhinolaryngology, Head and Neck Surgery, Yokohama City University, Kanagawa, Japan;

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HIROKI SATO

1Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan;

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TAKAHITO KONDO

1Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan;

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KUNHIKO TOKASHIKI

1Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan;

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KENJI HANYU

1Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan;

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TAKUMA KISHIDA

1Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan;

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TATSUYA ITO

1Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan;

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GAI YAMASHITA

1Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan;

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TATSUO MASUBUCHI

6Department of Head and Neck Surgery, Chibanishi General Hospital, Chiba, Japan;

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YUICHIRO TADA

7Department of Head and Neck Oncology and Surgery, International University of Health and Welfare, Mita Hospital, Tokyo, Japan;

8Department of Otorhinolaryngology-Head and Neck Surgery, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan

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GO OMURA

2Department of Head and Neck Oncology, National Cancer Center Hospital, Tokyo, Japan;

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TAKU YAMASHITA

3Department of Otorhinolaryngology, Head and Neck Surgery, Kitasato University School of Medicine, Kanagawa, Japan;

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NOBUHIKO ORIDATE

5Department of Otorhinolaryngology, Head and Neck Surgery, Yokohama City University, Kanagawa, Japan;

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KIYOAKI TSUKAHARA

1Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan;

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Effectiveness of Pembrolizumab Monotherapy for Older Adults With Head and Neck Carcinoma by CPS Status

Anticancer Research Mar 2026, 46 (3) 1639-1650; DOI: 10.21873/anticanres.18059

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Effectiveness of Pembrolizumab Monotherapy for Older Adults With Head and Neck Carcinoma by CPS Status

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pembrolizumab
head and neck cancer
older adults
CPS

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