The Privileged Scaffold Quinoline in Derivatives With Anticancer Potential Mediated by Late Apoptosis

DENISE DIEDRICH; ELENILSON F. SILVA; JULIA B. WILLIG; THAÍS C. RUARO; NÁDIA M.G. COUTO; MICKAEL JEAN; GLORIA N.S. SILVA; DIOGO A. PILGER; ALINE R. ZIMMER; PIERRE V. WEGUE; SIMONE C.B. GNOATTO

doi:10.21873/anticanres.18042

Research ArticleExperimental Studies

The Privileged Scaffold Quinoline in Derivatives With Anticancer Potential Mediated by Late Apoptosis

DENISE DIEDRICH, ELENILSON F. SILVA, JULIA B. WILLIG, THAÍS C. RUARO, NÁDIA M.G. COUTO, MICKAEL JEAN, GLORIA N.S. SILVA, DIOGO A. PILGER, ALINE R. ZIMMER, PIERRE V. WEGUE and SIMONE C.B. GNOATTO

Anticancer Research March 2026, 46 (3) 1475-1487; DOI: https://doi.org/10.21873/anticanres.18042

DENISE DIEDRICH

1Laboratory of Phytochemistry and Organic Synthesis, Department of Raw Material Production, Federal University of Rio Grande do Sul, Porto Alegre, Brazil;

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ELENILSON F. SILVA

1Laboratory of Phytochemistry and Organic Synthesis, Department of Raw Material Production, Federal University of Rio Grande do Sul, Porto Alegre, Brazil;

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JULIA B. WILLIG

2Laboratory of Biochemical and Cytological Analysis, Postgraduate Program in Pharmaceutical Sciences, School of Pharmacy, Federal University of Rio Grande do Sul, Porto Alegre, Brazil;

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THAÍS C. RUARO

1Laboratory of Phytochemistry and Organic Synthesis, Department of Raw Material Production, Federal University of Rio Grande do Sul, Porto Alegre, Brazil;

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NÁDIA M.G. COUTO

1Laboratory of Phytochemistry and Organic Synthesis, Department of Raw Material Production, Federal University of Rio Grande do Sul, Porto Alegre, Brazil;

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MICKAEL JEAN

3Natural Products Syntheses and Medicinal Chemistry Laboratory, Rennes University 1, Rennes, France;

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GLORIA N.S. SILVA

4School of Pharmacy, Federal University of Bahia, Salvador, Brazil

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For correspondence: gloriasilva{at}ufba.br

DIOGO A. PILGER

2Laboratory of Biochemical and Cytological Analysis, Postgraduate Program in Pharmaceutical Sciences, School of Pharmacy, Federal University of Rio Grande do Sul, Porto Alegre, Brazil;

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ALINE R. ZIMMER

1Laboratory of Phytochemistry and Organic Synthesis, Department of Raw Material Production, Federal University of Rio Grande do Sul, Porto Alegre, Brazil;

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PIERRE V. WEGUE

3Natural Products Syntheses and Medicinal Chemistry Laboratory, Rennes University 1, Rennes, France;

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SIMONE C.B. GNOATTO

1Laboratory of Phytochemistry and Organic Synthesis, Department of Raw Material Production, Federal University of Rio Grande do Sul, Porto Alegre, Brazil;

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The Privileged Scaffold Quinoline in Derivatives With Anticancer Potential Mediated by Late Apoptosis

DENISE DIEDRICH, ELENILSON F. SILVA, JULIA B. WILLIG, THAÍS C. RUARO, NÁDIA M.G. COUTO, MICKAEL JEAN, GLORIA N.S. SILVA, DIOGO A. PILGER, ALINE R. ZIMMER, PIERRE V. WEGUE, SIMONE C.B. GNOATTO

Anticancer Research Mar 2026, 46 (3) 1475-1487; DOI: 10.21873/anticanres.18042

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The Privileged Scaffold Quinoline in Derivatives With Anticancer Potential Mediated by Late Apoptosis

DENISE DIEDRICH, ELENILSON F. SILVA, JULIA B. WILLIG, THAÍS C. RUARO, NÁDIA M.G. COUTO, MICKAEL JEAN, GLORIA N.S. SILVA, DIOGO A. PILGER, ALINE R. ZIMMER, PIERRE V. WEGUE, SIMONE C.B. GNOATTO

Anticancer Research Mar 2026, 46 (3) 1475-1487; DOI: 10.21873/anticanres.18042

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Keywords

Quinoline
anticancer derivatives
cervical cancer
chronic myeloid leukemia

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