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Research ArticleExperimental Studies

Adenosine Inhibits Cholangiocarcinoma by a Concurrent Activation of AMPK and mTORC1 Signaling Pathways

JOMNARONG LERTSUWAN, JISNUSON SVASTI and JUTAMAAD SATAYAVIVAD
Anticancer Research March 2026, 46 (3) 1449-1460; DOI: https://doi.org/10.21873/anticanres.18040
JOMNARONG LERTSUWAN
1Laboratory of Immunology, Chulabhorn Research Institute, Bangkok, Thailand;
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  • For correspondence: jomnarong{at}cri.or.th
JISNUSON SVASTI
2Laboratory of Biochemistry, Chulabhorn Research Institute, Bangkok, Thailand;
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JUTAMAAD SATAYAVIVAD
3Laboratory of Pharmacology, Chulabhorn Research Institute, Bangkok, Thailand
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  • For correspondence: jutamaad{at}cri.or.th
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Article Information

vol. 46 no. 3 1449-1460
DOI 
https://doi.org/10.21873/anticanres.18040
PMID 
41760280

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received November 20, 2025
  • Revision received December 15, 2025
  • Accepted December 18, 2025
  • Published online February 27, 2026.

Copyright & Usage 
Copyright © 2026 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. JOMNARONG LERTSUWAN1⇑,
  2. JISNUSON SVASTI2 and
  3. JUTAMAAD SATAYAVIVAD3⇑
  1. 1Laboratory of Immunology, Chulabhorn Research Institute, Bangkok, Thailand;
  2. 2Laboratory of Biochemistry, Chulabhorn Research Institute, Bangkok, Thailand;
  3. 3Laboratory of Pharmacology, Chulabhorn Research Institute, Bangkok, Thailand
  1. Associate Professor Jutamaad Satayavivad, Chulabhorn Research Institute, 54 Kamphaeng Phet 6, Talat Bang Khen, Lak Si, Bangkok 10210, Thailand. Tel: +66 25538555 ext. 8539/8540, e-mail: jutamaad{at}cri.or.th (JS)
  2. Dr. Jomnarong Lertsuwan, Chulabhorn Research Institute, 54 Kamphaeng Phet 6, Talat Bang Khen, Lak Si, Bangkok 10210, Thailand. Tel: +66 25538555 ext. 8539/8540, e-mail: jomnarong{at}cri.or.th (JL)
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Anticancer Research: 46 (3)
Anticancer Research
Vol. 46, Issue 3
March 2026
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Adenosine Inhibits Cholangiocarcinoma by a Concurrent Activation of AMPK and mTORC1 Signaling Pathways
JOMNARONG LERTSUWAN, JISNUSON SVASTI, JUTAMAAD SATAYAVIVAD
Anticancer Research Mar 2026, 46 (3) 1449-1460; DOI: 10.21873/anticanres.18040

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Adenosine Inhibits Cholangiocarcinoma by a Concurrent Activation of AMPK and mTORC1 Signaling Pathways
JOMNARONG LERTSUWAN, JISNUSON SVASTI, JUTAMAAD SATAYAVIVAD
Anticancer Research Mar 2026, 46 (3) 1449-1460; DOI: 10.21873/anticanres.18040
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Keywords

  • Adenosine
  • cholangiocarcinoma
  • AMPK
  • mTORC1
  • autophagy
  • ER stress
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