Table of Contents

PROCEEDINGS OF THE 28TH ANNUAL MEETING OF THE JAPANESE ASSOCIATION FOR BIOTHERAPEUTICS

• Open Access

  Preface

  Takeo Fukushima

  Anticancer Research August 2025, 45 (8) 3399; DOI: https://doi.org/10.21873/anticanres.17701

• Review

  • Open Access

    3D-floating Culture for Cancer Research: A Mini-review

    AKIKO FUKUYAMA, TAKANORI KITAGUCHI, KAZUMASA YOSHIDA, TAICHI MATSUMOTO, KAZUHIRO KOIKAWA, MICHITAKA NAKANO, GEN MARUTA, HISANORI MAEOKA, SHUHEI ISHIKURA, SENJI SHIRASAWA and TOSHIYUKI TSUNODA

    Anticancer Research August 2025, 45 (8) 3401-3408; DOI: https://doi.org/10.21873/anticanres.17702

• Experimental Studies

  • Open Access

    Proteomic and Metabolomic Analyses of Adipose-derived Mesenchymal Stem Cell Exosomes and Culture Supernatants

    TOYOFUMI HIRAKAWA, TAMOTSU KATO, YUMIKO NAKANISHI, DAICHI URUSHIYAMA, KOHEI MIYATA, TSUKASA BABA, HIROSHI OHNO, SHIN’ICHIRO YASUNAGA, FUSANORI YOTSUMOTO and SHINGO MIYAMOTO

    Anticancer Research August 2025, 45 (8) 3409-3424; DOI: https://doi.org/10.21873/anticanres.17703
  • Open Access

    Combination of 3-(Trihydroxygermyl)propanoic Acid (THGP) and Lipopolysaccharide Promotes Macrophage Differentiation to M1, and Antitumor Activity

    JUNYA AZUMI, TOMOYA TAKEDA, YASUHIRO SHIMADA, HISASHI ASO, HIROYUKI INAGAWA and TAKASHI NAKAMURA

    Anticancer Research August 2025, 45 (8) 3425-3440; DOI: https://doi.org/10.21873/anticanres.17704
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    Molecular Characterization and Therapeutic Implications of MYD88 and CDKN2A in Primary CNS Lymphoma

    RYOUTA TAOMOTO, MIKIKO AOKI, TOSHIYUKI ENOMOTO, TOORU INOUE, KAZUKI NABESHIMA, MAKOTO HAMASAKI and HIROSHI ABE

    Anticancer Research August 2025, 45 (8) 3441-3450; DOI: https://doi.org/10.21873/anticanres.17705
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    Effect of Sulfonamide Group Modification on Celecoxib: Molecular Features of Matrix Metalloproteinase Interactive UTX-121 Derivative

    KAZUTO OHKURA, ATSUSHI TABATA and YOSHIHIRO UTO

    Anticancer Research August 2025, 45 (8) 3451-3457; DOI: https://doi.org/10.21873/anticanres.17706
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    Antioxidant Effects of Bidens Pilosa Extract Protect RAW 264.7 Cells from Cisplatin-induced Cytotoxicity

    KIHIRO SHIMIZU, AKO KUDO, TOKO IIDA, KEISUKE SATO, AKIFUMI NAKATA, KENICHI KOMATU, KAZUKI TAKAI and KOJI WAKAME

    Anticancer Research August 2025, 45 (8) 3459-3467; DOI: https://doi.org/10.21873/anticanres.17707

• Clinical Studies

  • Open Access

    Nuclear Localization of Chitinase 3-like 1 Is a Novel Biomarker for Detecting the Early Stage of Inflammation-associated Dysplasia in the Oral Cavity

    YUI TERATANI, TAKAYUKI SADANAGA, SIYUAN WANG, JINGO KUSUKAWA and EMIKO MIZOGUCHI

    Anticancer Research August 2025, 45 (8) 3469-3478; DOI: https://doi.org/10.21873/anticanres.17708
  • Open Access

    Comparison of Comprehensive Genomic Profiling Testing “Ion Torrent Genexus Sequencer” With FoundationOne

    KENJI FUJIYOSHI, RIE SUGIHARA, NAOKI MIYAMOTO, YORIKO WATANABE, TOMOYA SUDO, SANAE NUMATA, JUN AKIBA, HIDEYUKI ABE, YUKA ICHINOSE, KENJI INOUE, SHUICHI OZONO, TAKEHARU ONO, KENTARO ORIOKA, MASAKI KASHIHARA, RYOUSUKE KAJIWARA, HIROYUKI KAWANO, AKIHIKO KAWAHARA, RYUTA TAKASE, UHI TOH, KAZUAKI HASHIMOTO, TORU HISAKA, SHINGO HIRAI, MASAHIRO MITSUOKA, DAIKI MIYAZAKI, FUMI YOSHITOMI, KEN YAMAMOTO, HIROHITO UMENO, MASAHISA NOMURA and YOSHIKI NAITO

    Anticancer Research August 2025, 45 (8) 3479-3486; DOI: https://doi.org/10.21873/anticanres.17709
  • Open Access

    Characterization of Tumor Immune Microenvironment in Meningiomas: Correlation of Tumor-infiltrating Lymphocyte Aggregates With Tumor Grade

    TOSHIAKI INOMO, MASASUKE OHNO, TORU NAGASAKA, SHUNICHIRO KURAMITSU, EIJI ITO, TADASHI WATANABE and MITSUGU FUJITA

    Anticancer Research August 2025, 45 (8) 3487-3496; DOI: https://doi.org/10.21873/anticanres.17710
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    Standardized Technique for Minimally Invasive Right Posterior Sectionectomy for Hepatocellular Carcinoma: A Propensity Score-matched Study

    HISAMUNE SAKAI, YUICHI GOTO, SHOGO FUKUTOMI, SHOICHIROU ARAI, RYUTA MIDORIKAWA, KAZUAKI HASHIMOTO, DAIKI MIYAZAKI, MASANORI AKASHI, NOBUYA ISHIBASHI, KOJI OKUDA, FUMIHIKO FUJITA and TORU HISAKA

    Anticancer Research August 2025, 45 (8) 3497-3510; DOI: https://doi.org/10.21873/anticanres.17711
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    CD155 Expression Predicts Poor Prognosis in OTSCC and Correlates With TIGIT Expression and Tumor Budding

    SHOICHI KIMURA, MIKIKO AOKI, KENSUKE NISHI, TORANOSHIN TAKEUCHI, TAKAFUMI YAMANO, TOSHIFUMI SAKATA, TOSHIYUKI TSUNODA and MAKOTO HAMASAKI

    Anticancer Research August 2025, 45 (8) 3511-3522; DOI: https://doi.org/10.21873/anticanres.17712
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    Short- and Long-term Outcomes of Laparoscopic Versus Open Repeat Hepatectomy for Hepatocellular Carcinoma

    SHOGO FUKUTOMI, HISAMUNE SAKAI, YUICHI GOTO, KAZUAKI HASHIMOTO, RYUTA MIDORIKAWA, SHOICHIRO ARAI, MASANORI AKASHI, TARO ISOBE, TAKEHUMI YOSHIDA, NAOKI MORI, NOBUYA ISHIBASHI, FUMIHIKO FUJITA and TORU HISAKA

    Anticancer Research August 2025, 45 (8) 3523-3530; DOI: https://doi.org/10.21873/anticanres.17713
  • Open Access

    Novel UF-5000-based Detection, Integrating Inflammatory Parameters, for Urothelial Carcinoma of the Urinary Bladder

    KAZUHIRO OKADA, YOSHIKI NAITO, SAORI IRIE, CHIKA NAKAMOTO, KENJI KUBOYAMA, TOSHIKI TARUMIZU, MISAKI IKEDA, YUKO TAKUMA, RYO MAKINO, AKIHIKO KAWAHARA and HIROYUKI KAWANO

    Anticancer Research August 2025, 45 (8) 3531-3541; DOI: https://doi.org/10.21873/anticanres.17714
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    Development and External Validation of Machine Learning-based Models for Predicting Survival Outcomes in Endometrial Cancer: A Population-based Study

    MUNETOSHI AKAZAWA, KAZUNORI HASHIMOTO and HIROAKI NAGANO

    Anticancer Research August 2025, 45 (8) 3543-3551; DOI: https://doi.org/10.21873/anticanres.17715
  • Open Access

    Clinical Evaluation of Immune Cell Therapy in Esophageal Cancer Resistant to Immunochemotherapy

    RISHU TAKIMOTO, TAKASHI KAMIGAKI, SACHIKO OKADA, HIROSHI IBE, ERI OGUMA, AYA OHNO and SHIGENORI GOTO

    Anticancer Research August 2025, 45 (8) 3553-3559; DOI: https://doi.org/10.21873/anticanres.17716
  • Open Access

    Late-onset Colonic Graft and Overlying Skin Necrosis 15 Years After Esophagectomy and Gastrectomy: A Case Report

    KOKI FUJIWARA, JUNKO MUKOHYAMA, FUMIHIKO KATO, AYU KATO, SOJUN HOSHIMOTO, MASAHIRO SHINODA, YOSHIFUMI IKEDA and OSAMU ITANO

    Anticancer Research August 2025, 45 (8) 3561-3566; DOI: https://doi.org/10.21873/anticanres.17717
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    Endometrial Cancer Metastatic to the Sigmoid Colon and Pelvic Retroperitoneal Space: A Case Report

    JUNKO MUKOHYAMA, ITARU SAITO, SATOSHI MOCHIZUKI, YASUNORI OTA, GO ITO, JUN IMAIZUMI, SATOKO MONMA, NAOKI SAKUYAMA, SUSUMU AIKOU and DAI SHIDA

    Anticancer Research August 2025, 45 (8) 3567-3573; DOI: https://doi.org/10.21873/anticanres.17718