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Research ArticleExperimental Studies

Magnolol Suppresses Osteosarcoma Progression via Apoptosis Induction and EGFR/AKT Pathway Inactivation in a U-2 OS Xenograft Model

CHI-HUAN LI, CHIA-JUNG TSAI, FEI-TING HSU, BING-RU PENG, MAO-CHI WENG, TSAI-LAN LIAO, HSIAO-CHIA WANG, CHING-YU HAN and JIANN-HWA CHEN
Anticancer Research July 2025, 45 (7) 2949-2961; DOI: https://doi.org/10.21873/anticanres.17662
CHI-HUAN LI
1Department of Orthopedics, Chang Bing Show Chwan Memorial Hospital, Changhua, Taiwan, R.O.C.
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CHIA-JUNG TSAI
2Department of Medical Imaging and Radiological Sciences, I-Shou University, Kaohsiung, Taiwan, R.O.C.
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FEI-TING HSU
3Department of Life Sciences, National Central University, Taoyuan, Taiwan, R.O.C.
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BING-RU PENG
4Graduate Institute of Radiological Science Central Taiwan University of Science and Technology Takun, Taichung, Taiwan, R.O.C.
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MAO-CHI WENG
5Department of Isotope Application Research, National Atomic Research Institute, Taoyuan, Taiwan, R.O.C.
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TSAI-LAN LIAO
6Department of Dentistry, National Yang Ming Chiao Tung University, Taipei, Taiwan, R.O.C.
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HSIAO-CHIA WANG
7Department of Emergency Medicine, Cathay General Hospital, Taipei, Taiwan, R.O.C.
8School of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan, R.O.C.
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CHING-YU HAN
9Department of Emergency Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan, R.O.C.
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  • For correspondence: sunrainhan{at}gmail.com
JIANN-HWA CHEN
7Department of Emergency Medicine, Cathay General Hospital, Taipei, Taiwan, R.O.C.
8School of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan, R.O.C.
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  • For correspondence: chenjiannhwa{at}yahoo.com.tw
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Anticancer Research: 45 (7)
Anticancer Research
Vol. 45, Issue 7
July 2025
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Magnolol Suppresses Osteosarcoma Progression via Apoptosis Induction and EGFR/AKT Pathway Inactivation in a U-2 OS Xenograft Model
CHI-HUAN LI, CHIA-JUNG TSAI, FEI-TING HSU, BING-RU PENG, MAO-CHI WENG, TSAI-LAN LIAO, HSIAO-CHIA WANG, CHING-YU HAN, JIANN-HWA CHEN
Anticancer Research Jul 2025, 45 (7) 2949-2961; DOI: 10.21873/anticanres.17662

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Magnolol Suppresses Osteosarcoma Progression via Apoptosis Induction and EGFR/AKT Pathway Inactivation in a U-2 OS Xenograft Model
CHI-HUAN LI, CHIA-JUNG TSAI, FEI-TING HSU, BING-RU PENG, MAO-CHI WENG, TSAI-LAN LIAO, HSIAO-CHIA WANG, CHING-YU HAN, JIANN-HWA CHEN
Anticancer Research Jul 2025, 45 (7) 2949-2961; DOI: 10.21873/anticanres.17662
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Show more Experimental Studies

Keywords

  • magnolol
  • osteosarcoma
  • apoptosis
  • EGFR
  • AKT
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