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Table of Contents

July 2025; Volume 45,Issue 7

Special Issue on New Anticancer Agents

Reviews

  • Open Access
    Cancer Stem Cells in Glioblastoma: The Role of the mTOR Pathway
    MONICA C. MUREB, SABRINA L. ZELLER, HAYLEN T. ROSBERGER, ERIS SPIROLLARI, MOHAN DAS, SIMON J. HANFT, CHIRAG D. GANDHI and MEENA JHANWAR-UNIYAL
    Anticancer Research July 2025, 45 (7) 2697-2709; DOI: https://doi.org/10.21873/anticanres.17640
  • Open Access
    Immunotherapy and Chemotherapy for Advanced or Recurrent Endometrial Carcinoma
    JOHN P. MICHA, RANDY D. BOHART, JOSHUA P. GORMAN and BRAM H. GOLDSTEIN
    Anticancer Research July 2025, 45 (7) 2711-2717; DOI: https://doi.org/10.21873/anticanres.17641
  • Open Access
    Cannabinoids as Potential Therapeutic Agents in the Treatment of Pancreatic Cancer
    SABRINA BIMONTE, DAVIDE NOCERINO, MARCO CRISCI, DANIELA SCHIAVO, VITTORIO ALBINO, MAURIZIO MARCHESINI and ARTURO CUOMO
    Anticancer Research July 2025, 45 (7) 2719-2728; DOI: https://doi.org/10.21873/anticanres.17642
  • Open Access
    Unlocking New Frontiers in Breast Cancer: The Role of the Tumor Microenvironment, Cutting-Edge Therapies, and Immunotherapy
    DOUA KAMYAN, NOHA M. ELEMAM, NOURA ALKHAYYAL, IMAN M. TALAAT and RIYAD BENDARDAF
    Anticancer Research July 2025, 45 (7) 2729-2747; DOI: https://doi.org/10.21873/anticanres.17643

Experimental Studies

  • Open Access
    Fucoidan Treatment Leads to Attenuated Growth Factor Signaling and Reduced Proliferation in Neuroblastoma Cells
    NIKLAS WEBER, NINA SOPHIE POMMERT, MEIKE KAEHLER, INGOLF CASCORBI, SUSANNE ALBAN and VICKI WAETZIG
    Anticancer Research July 2025, 45 (7) 2749-2762; DOI: https://doi.org/10.21873/anticanres.17644
  • Open Access
    Effects of Azelastine on Glioblastoma Cells
    YUKI UEMICHI, SEINA YASUDA, MIYUKI MABUCHI, SHUHEI NAKAO, SHUJI NAGANO and TADASHI SHIMIZU
    Anticancer Research July 2025, 45 (7) 2763-2771; DOI: https://doi.org/10.21873/anticanres.17645
  • Open Access
    The Triple Combination of Recombinant Methioninase, Rapamycin, and Chloroquine Synergistically Eradicates HCT116 Colon Cancer Cells
    JINSOO KIM, QINGHONG HAN, BYUNG MO KANG, KOHEI MIZUTA, YOHEI ASANO, MICHAEL BOUVET and ROBERT M. HOFFMAN
    Anticancer Research July 2025, 45 (7) 2773-2779; DOI: https://doi.org/10.21873/anticanres.17646
  • Open Access
    Apigenin-induced Apoptosis in Lung Adenocarcinoma A549 Cells: Involvement in IFNA2, TNF, and SPON2 With Different Time Points
    RIEKO AIDA, KAZUNORI OKANO, KYOKO NAKATA and HIROMI HAGIWARA
    Anticancer Research July 2025, 45 (7) 2781-2790; DOI: https://doi.org/10.21873/anticanres.17647
  • You have access
    Heterogeneous c-Met Activation in Osteosarcoma Dictates Synergistic Vulnerability to Combined c-Met Inhibition and Methotrexate Therapy
    GUIDONG LI, HIROYUKI KAWASHIMA, TARO SASAKI, TAKASHI ARIIZUMI, NAOKI OIKE and AKIRA OGOSE
    Anticancer Research July 2025, 45 (7) 2791-2806; DOI: https://doi.org/10.21873/anticanres.17648
  • You have access
    Development of a Benzoxazine-derived Inhibitor Targeting Epithelial-to-Mesenchymal Transition in Lung Cancer
    NAPHATSON PHANSOM, ZIN ZIN EI, BHURICHAYA INNETS, WORAWAT WATTANATHANA, THEERA RITTIROD, ACHARAWAN THONGMEE, KEERATI JOYJAMRAS and PITHI CHANVORACHOTE
    Anticancer Research July 2025, 45 (7) 2807-2815; DOI: https://doi.org/10.21873/anticanres.17649
  • Open Access
    The Conditions of Non-rescuability of Methioninase-treated Cancer Cells by Methionine Replenishment: The Point of No Return
    BYUNG MO KANG, QINGHONG HAN, SHUKUAN LI, KOHEI MIZUTA, JIN SOO KIM, YOHEI ASANO, MICHAEL BOUVET and ROBERT M. HOFFMAN
    Anticancer Research July 2025, 45 (7) 2817-2823; DOI: https://doi.org/10.21873/anticanres.17650
  • Open Access
    The Combination of the Autophagy Inhibitor Chloroquine and Recombinant Methioninase Has Selective Synergistic Efficacy on Human Colon Cancer Cells But Not on Normal Human Fibroblasts
    YOHEI ASANO, QINGHONG HAN, SHUKUAN LI, KOHEI MIZUTA, BYUNG MO KANG, JIN SOO KIM, YUTA MIYASHI, NORIO YAMAMOTO, KATSUHIRO HAYASHI, HIROAKI KIMURA, SHINJI MIWA, KENTARO IGARASHI, TAKASHI HIGUCHI, SEI MORINAGA, HIROYUKI TSUCHIYA, SATORU DEMURA and ROBERT M. HOFFMAN
    Anticancer Research July 2025, 45 (7) 2825-2831; DOI: https://doi.org/10.21873/anticanres.17651
  • You have access
    Artogomezianone Inhibits EGFR and Promotes Apoptosis in Non-small Cell Lung Cancer Cells
    WORAWICH SOMBOONVORAVONG, KORRAKOD PETSRI, SATAPAT RACHA, NICHARAT SRIRATANASAK, KEERATI JOYJAMRAS, BOONCHOO SRITULARAK and PITHI CHANVORACHOTE
    Anticancer Research July 2025, 45 (7) 2833-2845; DOI: https://doi.org/10.21873/anticanres.17652
  • You have access
    Damnacanthal Suppresses TCF4 Expression in Colorectal Cancer Cells
    JAEHAK LEE, HAYEUN KIM, JIYOUNG MOON, THARARAT NUALSANIT, WORAPAPAR TREESUPPHARAT and SEUNG JOON BAEK
    Anticancer Research July 2025, 45 (7) 2847-2858; DOI: https://doi.org/10.21873/anticanres.17653
  • You have access
    Macranthoside B Enhances Paclitaxel-induced Human Cervical Cancer Cell Apoptosis Through ROS-JNK Pathway
    MENGLING LI, JIE YAN, SHUAIJIE WEI, SONGJI ZHAO, ZHENG-GUO CUI and XIAOPENG TONG
    Anticancer Research July 2025, 45 (7) 2859-2870; DOI: https://doi.org/10.21873/anticanres.17654
  • You have access
    Cytotoxic and Metalloproteinase-inhibitory Effects of Ellagic Acid Against Oral Squamous Cell Carcinoma
    PATRICIA MARIA WIZIACK ZAGO, LUIZA RODRIGUES HELLMEISTER, LUCAS NOVAES TEIXEIRA, RUI BARBOSA DE BRITO JUNIOR and ELIZABETH FERREIRA MARTINEZ
    Anticancer Research July 2025, 45 (7) 2871-2880; DOI: https://doi.org/10.21873/anticanres.17655
  • You have access
    Study of the Cytotoxic and Antitumor Effect of L-lysine-α-oxidase from Trichoderma harzianum Rifai
    IRINA P. SMIRNOVA, EKATERINA V. NEBORAK, VICTOR F. LARICHEV, LYUDMILA A. GAVRILYUK and DMITRY D. ZHDANOV
    Anticancer Research July 2025, 45 (7) 2881-2889; DOI: https://doi.org/10.21873/anticanres.17656
  • You have access
    Anti-cancer Effects of a Novel Curcumin Derivative, 4,4-Diallyl Curcumin Bis(2,2-Hydroxymethyl)Propanoate (35e), on Radio-resistant Colorectal Cancer Cells
    CHING-WEN HUANG, JAI-SING YANG, YUH-FENG TSAI, SHENG-CHU KUO, YU-NING JUAN, MENG-WEI LIN, YU-JEN CHIU and CHUNG-HUA HSU
    Anticancer Research July 2025, 45 (7) 2891-2904; DOI: https://doi.org/10.21873/anticanres.17657
  • You have access
    High Antitumor Effects and Reduced Side Effects of Doxorubicin Prodrug Active Only Under Hypoxic Conditions
    KOKI YOSHIOKA, TAISUKE FURUTA, TOMOHIKO SAKUDA, AKIHIRO ODA, YUTAKA IKEDA, SHIGERU MIYAKI, YUKIO NAGASAKI and NOBUO ADACHI
    Anticancer Research July 2025, 45 (7) 2905-2916; DOI: https://doi.org/10.21873/anticanres.17658
  • You have access
    Effective Targeting of Glioma Stem Cells by BSJ-04-122, a Novel Covalent MKK4/7 Dual Inhibitor
    KAZUKI NAKAMURA, YASUFUMI ITO, SENRI TAKENOUCHI, YURIKA NAKAGAWA-SAITO, SHUHEI SUZUKI, KEITA TOGASHI, ASUKA SUGAI, YUTA MITOBE, YUKIHIKO SONODA, CHIFUMI KITANAKA and MASASHI OKADA
    Anticancer Research July 2025, 45 (7) 2917-2924; DOI: https://doi.org/10.21873/anticanres.17659
  • You have access
    The Polyphenol (−)-Epigallocatechin-3-gallate (EGCG) Inhibits the Proliferation of Gastric Cancer Cells and Alters microRNA Signatures
    KOTA SASAKI, KOJI FUJITA, SHINTARO FUJIHARA, HISAKAZU IWAMA, ATSUO KITAOKA, FUMIYUKI SUETSUGU, SHIMA MIMURA, JOJI TANI, ASAHIRO MORISHITA, TSUTOMU MASAKI and HIDEKI KOBARA
    Anticancer Research July 2025, 45 (7) 2925-2936; DOI: https://doi.org/10.21873/anticanres.17660
  • You have access
    Antitumor Effects of Epigallocatechin-3-Gallate on Colorectal Cancer: An In Vitro and In Vivo Study
    FUMIYUKI SUETSUGU, TOMOKO TADOKORO, KOJI FUJITA, SHINTARO FUJIHARA, KOTA SASAKI, ERIKA OMAYU, KAHO NAKATANI, YUKIKO KOYAMA, KAZUHIRO KOZUKA, TAKANORI MATSUI, MAI NAKAHARA, KYOKO OURA, ATSUO KITAOKA, TATSUO YACHIDA, JOJI TANI, ASAHIRO MORISHITA, TSUTOMU MASAKI and HIDEKI KOBARA
    Anticancer Research July 2025, 45 (7) 2937-2947; DOI: https://doi.org/10.21873/anticanres.17661
  • You have access
    Magnolol Suppresses Osteosarcoma Progression via Apoptosis Induction and EGFR/AKT Pathway Inactivation in a U-2 OS Xenograft Model
    CHI-HUAN LI, CHIA-JUNG TSAI, FEI-TING HSU, BING-RU PENG, MAO-CHI WENG, TSAI-LAN LIAO, HSIAO-CHIA WANG, CHING-YU HAN and JIANN-HWA CHEN
    Anticancer Research July 2025, 45 (7) 2949-2961; DOI: https://doi.org/10.21873/anticanres.17662
  • You have access
    Integrating Network Pharmacology and Optimization of Preparation Methods to Enhance the Anticancer Effect of Cordyceps militaris on Lung Cancer
    HYE-LIN KIM, JUNKYU PARK, HYO IN KIM, MINA BOO, JAE HEON SIM, HARIM KIM, HYUNYOUNG CHOI, SUHYEON AN, HYUNSOO YANG, SUJIN SHIN, YOHAN HAN, HYOJEONG KIM, JINBONG PARK and KYUNGJIN LEE
    Anticancer Research July 2025, 45 (7) 2963-2984; DOI: https://doi.org/10.21873/anticanres.17663
  • You have access
    Tetrahydroindazolone-substituted Benzamide Compound W-H4 Induces Apoptosis and Autophagy of Acute Myeloid Leukemia Cells
    YAWEN LI, SHENG WANG, HAN WANG, JIAHUA ZOU, CHUIWEN QIAN and ZHONG LIU
    Anticancer Research July 2025, 45 (7) 2985-2996; DOI: https://doi.org/10.21873/anticanres.17664
  • You have access
    ITGAV Regulation of LGALS3BP-JUNB Axis Facilitates the Cell-to-Cell Adhesion and Invasiveness of Hepatic Cancer Cells
    HYUN JEONG SHIM, MYONG-SUK PARK, WOO-KYUN BAE, SANG-HEE CHO, IK-JOO CHUNG and DAE-HWAN KIM
    Anticancer Research July 2025, 45 (7) 2997-3008; DOI: https://doi.org/10.21873/anticanres.17665
  • You have access
    Piperine Targets MAOB and Enhances Temozolomide-induced Cytotoxicity in Glioblastoma Cell Lines
    HYEON JI KIM, CHANG-HOON SHIN, TAE-JUN KIM and DO-YEON KIM
    Anticancer Research July 2025, 45 (7) 3009-3020; DOI: https://doi.org/10.21873/anticanres.17666
  • You have access
    Resveratrol Derivatives Inhibit Pro-survival Akt Signaling Pathway in Lung Cancer
    BHURICHAYA INNETS, SATAPAT RACHA, ZIN ZIN EI, NICHARAT SRIRATANASAK and PITHI CHANVORACHOTE
    Anticancer Research July 2025, 45 (7) 3021-3029; DOI: https://doi.org/10.21873/anticanres.17667
  • You have access
    Physalin F Inhibits Cell Viability and Induces Apoptosis in Non-small Cell Lung Cancer Cells
    JHY-MING LI, KAO-TAI YANG and CHEAN-PING WU
    Anticancer Research July 2025, 45 (7) 3031-3044; DOI: https://doi.org/10.21873/anticanres.17668
  • You have access
    Amentoflavone Enhances the Anti-tumor Activity of Regorafenib by Promoting Apoptosis and Inhibiting NF-κB–mediated Metastasis in Hepatocellular Carcinoma
    KUANG-HSUAN LIN, CHIA-JUNG TSAI, YING-TZU CHEN, RONG-FONG LIN, FEI-TING HSU, CHE-CHENG SU and YU-CHENG KUO
    Anticancer Research July 2025, 45 (7) 3045-3058; DOI: https://doi.org/10.21873/anticanres.17669
  • You have access
    Adiponectin Receptor Agonist Suppresses Human Colorectal Cancer
    MAI LY THI NGUYEN, LAN ANH BUI, CHI PHAM, PHUONG LINH THI NHAM, VAN MAO CAN, TRAN DUY HAI DOAN, PRZEMYSLAW BOZKO, KHAC CUONG BUI and LINH TOAN NGUYEN
    Anticancer Research July 2025, 45 (7) 3059-3068; DOI: https://doi.org/10.21873/anticanres.17670
  • You have access
    Bis-type Triaziquone Induces Apoptotic Effects in Human OEC-M1 Oral Cancer Cells
    CHUNG-CHI HSU, BU-MIIN HUANG, YENG-TING WU, CHIH-CHUN WANG, CHIH-CHIEH TAO, YUH-LING LIN and YU-YAN LAN
    Anticancer Research July 2025, 45 (7) 3069-3075; DOI: https://doi.org/10.21873/anticanres.17671
  • You have access
    A Novel Three Small Molecule Inhibitor Combination Therapy For Prostate Cancer
    UMMUHAN DEMIR, HILAL BADOGLU, IREM NUR CETIN and MUHAMMED YASAR BENER
    Anticancer Research July 2025, 45 (7) 3077-3087; DOI: https://doi.org/10.21873/anticanres.17672
  • You have access
    Ketone Bodies Inhibit Growth of Hepatoblastoma and Rhabdoid Tumor of the Kidney Cells
    ERI MUTO-FUJITA, BIN YAMAOKA, NAOKO ABE, KYOKO FUJIWARA and SHUICHIRO UEHARA
    Anticancer Research July 2025, 45 (7) 3089-3097; DOI: https://doi.org/10.21873/anticanres.17673
  • You have access
    Periostin Promotes Invasiveness and Metastasis of Oral Cancer via Epithelial-mesenchymal Transition
    SEONGJUN WON, YOUNG-SOOL HAH, SO YOUNG CHEON, CHAE DONG YIM, SANG-WOOK PARK, SEUNG-JUN LEE, JI HYUN SEO and JUNG JE PARK
    Anticancer Research July 2025, 45 (7) 3099-3115; DOI: https://doi.org/10.21873/anticanres.17674
  • You have access
    Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Enhance Cisplatin-induced Apoptotic Effects via the ROS-Fas Pathway in Human NPC-TW01 Nasopharyngeal Carcinoma Cells
    YINGXIAO LI, BU-MIIN HUANG, CHIH-CHIEH TAO and YU-YAN LAN
    Anticancer Research July 2025, 45 (7) 3117-3126; DOI: https://doi.org/10.21873/anticanres.17675

Clinical Studies

  • Open Access
    Low-dose Apalutamide in Non-metastatic Castration-resistant Prostate Cancer: A Case Series
    MINH DUNG NGUYEN, JOHAN ROSE DITE MODESTINE, YANNICK DJOUA, OLENA GOROBETS, VINCENT VINH-HUNG and CLAIRE F. VERSCHRAEGEN
    Anticancer Research July 2025, 45 (7) 3127-3136; DOI: https://doi.org/10.21873/anticanres.17676
  • Open Access
    Bone Toxicity Case Report Combining Encorafenib, Cetuximab and WNT974 in a Phase I Trial
    MARK T.J. VAN BUSSEL, NATHALIE BRAVENBOER, HUIB VAN ESSEN, PETUR SNAEBJORNSSON, NATASHA M. APPELMAN-DIJKSTRA, JAN HM SCHELLENS and FRANS L. OPDAM
    Anticancer Research July 2025, 45 (7) 3137-3147; DOI: https://doi.org/10.21873/anticanres.17677
  • Open Access
    Assessment of Breakthrough Cancer Pain Among Female Patients With Cancer: Knowledge, Management and Characterization in the IOPS-MS Study
    ANNA CRISPO, ASSUNTA LUONGO, DAVIDE NOCERINO, MARCO CASCELLA, MARCO CRISCI, FRANCESCA BIFULCO, DANIELA SCHIAVO, MAURIZIO MARCHESINI, SERGIO COLUCCIA, MELANIA PRETE, ALFONSO AMORE, EGIDIO CELENTANO, SABRINA BIMONTE and ARTURO CUOMO
    Anticancer Research July 2025, 45 (7) 3149-3164; DOI: https://doi.org/10.21873/anticanres.17678
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Anticancer Research: 45 (7)
Anticancer Research
Vol. 45, Issue 7
July 2025
  • Table of Contents
  • Table of Contents (PDF)
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  • Back Matter (PDF)
  • Ed Board (PDF)
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Issue highlights

  • Cancer Stem Cells in Glioblastoma: The Role of the mTOR Pathway
  • Low-dose Apalutamide in Non-metastatic Castration-resistant Prostate Cancer: A Case Series
  • Immunotherapy and Chemotherapy for Advanced or Recurrent Endometrial Carcinoma
  • Fucoidan Treatment Leads to Attenuated Growth Factor Signaling and Reduced Proliferation in Neuroblastoma Cells
  • The Triple Combination of Recombinant Methioninase, Rapamycin, and Chloroquine Synergistically Eradicates HCT116 Colon Cancer Cells
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Epithelial−Mesenchymal Transition in EGFR-TKI Acquired Resistant Lung Adenocarcinoma
Vitamin D Supplement Doses and Serum 25-Hydroxyvitamin D in the Range Associated with Cancer Prevention
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