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Research ArticleClinical Studies

Impact of Nivolumab Plus Chemotherapy on Conversion Therapy in Clinical Stage IVB HER2-negative Gastric Cancer

YUDAI HOJO, TOSHIHIKO TOMITA, MASATAKA IGETA, MOTOKI MURAKAMI, SHUGO KOHNO, EIICHIRO NAKAO, YOSHITAKA KITAYAMA, TATSURO NAKAMURA, YASUNORI KURAHASHI, YOSHINORI ISHIDA, SEIICHI HIROTA, SHINICHIRO SHINZAKI and HISASHI SHINOHARA
Anticancer Research May 2025, 45 (5) 2091-2102; DOI: https://doi.org/10.21873/anticanres.17583
YUDAI HOJO
1Department of Gastroenterological Surgery, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan;
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TOSHIHIKO TOMITA
2Department of Gastroenterology, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan;
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MASATAKA IGETA
3Department of Biostatistics, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan;
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MOTOKI MURAKAMI
1Department of Gastroenterological Surgery, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan;
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SHUGO KOHNO
1Department of Gastroenterological Surgery, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan;
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EIICHIRO NAKAO
1Department of Gastroenterological Surgery, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan;
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YOSHITAKA KITAYAMA
2Department of Gastroenterology, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan;
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TATSURO NAKAMURA
1Department of Gastroenterological Surgery, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan;
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YASUNORI KURAHASHI
1Department of Gastroenterological Surgery, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan;
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YOSHINORI ISHIDA
1Department of Gastroenterological Surgery, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan;
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SEIICHI HIROTA
4Department of Surgical Pathology, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan
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SHINICHIRO SHINZAKI
2Department of Gastroenterology, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan;
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HISASHI SHINOHARA
1Department of Gastroenterological Surgery, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan;
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  • For correspondence: shinohara{at}hyo-med.ac.jp
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Article Information

vol. 45 no. 5 2091-2102
DOI 
https://doi.org/10.21873/anticanres.17583
PMID 
40295068

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received March 7, 2025
  • Revision received March 20, 2025
  • Accepted March 21, 2025
  • Published online April 28, 2025.

Copyright & Usage 
Copyright © 2025 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. YUDAI HOJO1,
  2. TOSHIHIKO TOMITA2,
  3. MASATAKA IGETA3,
  4. MOTOKI MURAKAMI1,
  5. SHUGO KOHNO1,
  6. EIICHIRO NAKAO1,
  7. YOSHITAKA KITAYAMA2,
  8. TATSURO NAKAMURA1,
  9. YASUNORI KURAHASHI1,
  10. YOSHINORI ISHIDA1,
  11. SEIICHI HIROTA4,
  12. SHINICHIRO SHINZAKI2 and
  13. HISASHI SHINOHARA1⇑
  1. 1Department of Gastroenterological Surgery, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan;
  2. 2Department of Gastroenterology, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan;
  3. 3Department of Biostatistics, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan;
  4. 4Department of Surgical Pathology, Faculty of Medicine, Hyogo Medical University, Nishinomiya, Japan
  1. Hisashi Shinohara, MD, Ph.D., Department of Gastroenterological Surgery, Faculty of Medicine, Hyogo Medical University, 1-1 Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan. Tel: +81 0798456725, e-mail: shinohara{at}hyo-med.ac.jp
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Impact of Nivolumab Plus Chemotherapy on Conversion Therapy in Clinical Stage IVB HER2-negative Gastric Cancer
YUDAI HOJO, TOSHIHIKO TOMITA, MASATAKA IGETA, MOTOKI MURAKAMI, SHUGO KOHNO, EIICHIRO NAKAO, YOSHITAKA KITAYAMA, TATSURO NAKAMURA, YASUNORI KURAHASHI, YOSHINORI ISHIDA, SEIICHI HIROTA, SHINICHIRO SHINZAKI, HISASHI SHINOHARA
Anticancer Research May 2025, 45 (5) 2091-2102; DOI: 10.21873/anticanres.17583

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Impact of Nivolumab Plus Chemotherapy on Conversion Therapy in Clinical Stage IVB HER2-negative Gastric Cancer
YUDAI HOJO, TOSHIHIKO TOMITA, MASATAKA IGETA, MOTOKI MURAKAMI, SHUGO KOHNO, EIICHIRO NAKAO, YOSHITAKA KITAYAMA, TATSURO NAKAMURA, YASUNORI KURAHASHI, YOSHINORI ISHIDA, SEIICHI HIROTA, SHINICHIRO SHINZAKI, HISASHI SHINOHARA
Anticancer Research May 2025, 45 (5) 2091-2102; DOI: 10.21873/anticanres.17583
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Keywords

  • Gastric cancer
  • Nivolumab
  • Chemotherapy
  • conversion surgery
  • conversion therapy
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