Research ArticleExperimental Studies

Fluoxetine Suppresses Osteosarcoma Progression In Vivo by Inducing Apoptosis and Inhibiting the AKT/mTOR/NF-κB Signaling Pathway

YU-HSI CHEN, CHI-HUAN LI, SHIH-WEI LIU, FEI-TING HSU and MING-CHOU KU
Anticancer Research April 2025, 45 (4) 1465-1480; DOI: https://doi.org/10.21873/anticanres.17530

Article Information

vol. 45 no. 4 1465-1480
DOI 
https://doi.org/10.21873/anticanres.17530
PubMed 
40155004
Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received February 6, 2025
  • Revision received February 18, 2025
  • Accepted February 20, 2025
  • Published online March 28, 2025.
Copyright & Usage 
Copyright © 2025 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. YU-HSI CHEN1,*,
  2. CHI-HUAN LI2,*,
  3. SHIH-WEI LIU3,4,*,
  4. FEI-TING HSU5 and
  5. MING-CHOU KU1,6⇑
  1. 1Department of Orthopedics, Show Chwan Memorial Hospital, Changhua, Taiwan, R.O.C.;
  2. 2Department of Orthopedics, Chang Bing Show Chwan Memorial Hospital, Changhua, Taiwan, R.O.C.;
  3. 3Department of Emergency Medicine, National Yang Ming Chiao Tung University Hospital, I-Lan, Taiwan, R.O.C.;
  4. 4School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, R.O.C.;
  5. 5Department of Life Sciences, National Central University, Taoyuan, Taiwan, R.O.C.;
  6. 6Department of Medical Imaging and Radiological Sciences, Central Taiwan University of Science and Technology, Taichung, Taiwan, R.O.C.
  1. Ming-Chou Ku, Department of Orthopedics, Show Chwan Memorial Hospital, No. 6 Lugong Rd. Lukang Zhen, Changhua County 500, Taiwan, R.O.C. Tel: +886 975617088, e-mail: showjoeku{at}gmail.com

  1. ↵* These Authors contributed equally to this work.

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Fluoxetine Suppresses Osteosarcoma Progression In Vivo by Inducing Apoptosis and Inhibiting the AKT/mTOR/NF-κB Signaling Pathway
YU-HSI CHEN, CHI-HUAN LI, SHIH-WEI LIU, FEI-TING HSU, MING-CHOU KU
Anticancer Research Apr 2025, 45 (4) 1465-1480; DOI: 10.21873/anticanres.17530
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