Table of Contents

Clinical Studies

• Open Access

  PCD-CT Versus EID-CT in Imaging of Pancreatic Ductal Adenocarcinoma: A Prospective Comparative Pilot Study

  HAKON BLOMSTRAND, ERIK TESSELAAR, BERGTHOR BJÖRNSSON, WOLF BARTHOLOMÄ, TOMAS BJERNER, MICHAEL SANDBORG, NILS O. ELANDER and MISCHA WOISETSCHLÄGER

  Anticancer Research April 2025, 45 (4) 1547-1558; DOI: https://doi.org/10.21873/anticanres.17536
• Open Access

  Circulating Tumor DNA Methylation Is a Biomarker of Poor Recurrence-free Survival in Locally-Advanced Rectal Cancer

  KIICHI SUGIMOTO, TAKAHIRO IRIE, HIROTAKA MOMOSE, SAKI KOCHI, MIYUKI TOAKE, YUKI TSUCHIYA, RYOICHI TSUKAMOTO, KUMPEI HONJO, SHUN ISHIYAMA, MAKOTO TAKAHASHI, ROBERT M. HOFFMAN and KAZUHIRO SAKAMOTO

  Anticancer Research April 2025, 45 (4) 1559-1573; DOI: https://doi.org/10.21873/anticanres.17537
• Open Access

  The Impact of Body Mass Index on Sentinel Lymph Node Identification in Endometrial Cancer

  ROXANI DAMPALI, KONSTANTINOS NIKOLETTOS, IASON PSILOPATIS, EVANGELIA-GEORGIA KOSTAKI, ANDREAS JOHN PAPADOPOULOS, STEPHEN ATTARD-MONTALTO and OMER DEVAJA

  Anticancer Research April 2025, 45 (4) 1575-1581; DOI: https://doi.org/10.21873/anticanres.17538
• Open Access

  Nivolumab Plus 5-Fluorouracil/Leucovorin+Oxaliplatin for Gastric Cancer With Severe Peritoneal Metastasis

  KYOKO FURUSAWA, MITSUHIRO FURUTA, MISA ONISHI, TAKANORI HAMA, SHUNTARO ISHIKAWA, KEI HAYASHI, HIROSHI NAKANOMA, KAZUO SHIOTSUKI, KOHEI TAKIZAWA, NOZOMU MACHIDA, JUNJI FURUSE and SHIN MAEDA

  Anticancer Research April 2025, 45 (4) 1583-1592; DOI: https://doi.org/10.21873/anticanres.17539
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  Does Aggressive Versus Less Aggressive Non-operative Treatment of Large and Very Large (≥7 cm) Lung Cancers Matter?

  FEDERICO AMPIL, CARLOS PREVIGLIANO, KIM HEATH and AMY BOZEMAN

  Anticancer Research April 2025, 45 (4) 1593-1598; DOI: https://doi.org/10.21873/anticanres.17540
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  Association Between Kita-kyushu Lung Cancer Antigen-1 Expression in Gastric Cancer and Helicobacter pylori-infection Status

  NOBUE FUTAWATARI, TAKASHI FUKUYAMA, YUSUKE AKIMOTO, JUNJI MAEHARA, DAISUKE HIHARA, YOSUKE OKAMOTO, YUKI YOKOUCHI, KEI TAKAHASHI, MANABU WATANABE and YOSHIHISA SAIDA

  Anticancer Research April 2025, 45 (4) 1599-1606; DOI: https://doi.org/10.21873/anticanres.17541
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  Real-world Data of the Lung Cancer Compact Panel™ in Non-small Cell Lung Cancer Using Tissue Samples

  YOSHIHIKO TANIGUCHI, AKIHIRO TAMIYA, YUKARI KAMIYAMA, HITOSHI SUMITANI, YUKI IWAHASHI, AKIHIRO TSUKAGUCHI, EIJI SUGIMOTO, YUJI INAGAKI, KEIKO NAKAO, YOSHINOBU MATSUDA, MAIKO TAKEDA, TAKAHIKO KASAI, KYOICHI OKISHIO and SHIGEKI SHIMIZU

  Anticancer Research April 2025, 45 (4) 1607-1615; DOI: https://doi.org/10.21873/anticanres.17542
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  Sialic Acid-Fibronectin-negative and Vimentin-positive Breast Cancers Have Poor Prognoses due to Epithelial-Mesenchymal Transition

  HIROSHI TAKEYAMA, YOSHINOBU MANOME, MUNEYUKI KOYAMA, YUKIKO YOSHII, ERIKO TAGUCHI, AZUSA FUKE, TAKAAKI YAMASHITA, YOSHINOBU FUSE, ATUSHI FUSHIMI and HIROKO NOGI

  Anticancer Research April 2025, 45 (4) 1617-1629; DOI: https://doi.org/10.21873/anticanres.17543
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  Dosimetric Comparison of Brain Sparing Between HyperArc and GammaKnife for Single to Triple Brain Metastases

  YOSHIHIRO UEDA, KANJI MORI, SHINGO OHIRA, KAZUO TARUTANI, NAOYUKI KANAYAMA, AYAKO OKAMURA and KOJI KONISHI

  Anticancer Research April 2025, 45 (4) 1631-1641; DOI: https://doi.org/10.21873/anticanres.17544
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  Comparative Analysis of Outcomes for Patients With Advanced Renal Cell Carcinoma: Immuno-Oncology Era Versus Tyrosine Kinase Inhibitor Era in the IMDC Favorable-risk Group

  HIROKI ISHIHARA, YUKI NEMOTO, SHINSUKE MIZOGUCHI, KOICHI NISHIMURA, HIRONORI FUKUDA, KAZUHIKO YOSHIDA, HIROAKI SHIMMURA, YASUNOBU HASHIMOTO, JUNPEI IIZUKA, TSUNENORI KONDO and TOSHIO TAKAGI

  Anticancer Research April 2025, 45 (4) 1643-1652; DOI: https://doi.org/10.21873/anticanres.17545
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  Evaluation of Candidates for Upfront Docetaxel Therapy Among Patients With Metastatic Castration-sensitive Prostate Cancer from a Retrospective Multicenter Study (MAHOROBA study)

  YASUSHI NAKAI, KENTA ONISHI, TOMONORI NAKAHAMA, YORIAKI KAGEBAYASHI, KEN FUJIMOTO, AKIHIDE HIRAYAMA, ATSUSHI TOMIOKA, KENJI OTSUKA, TAKESHI OTANI, YOSHIHIRO MATSUMOTO, MASAHIRO TANAKA, NOBUO OYAMA, KIYOHIDE FUJIMOTO and NOBUMICHI TANAKA

  Anticancer Research April 2025, 45 (4) 1653-1660; DOI: https://doi.org/10.21873/anticanres.17546
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  Increased Expression of DDX39 in Uveal Melanoma Is Associated With Patient Prognosis

  SHIN-NOSUKE YAMASHITA, YOSHIATSU TANAKA, SHAJEDUL ISLAM, TAKAO KITAGAWA, KAZUHIRO TOKUDA, DURGA PAUDEL, SARITA GIRI, TOHRU OHTA, FUMIYA HARADA, HIROKI NAGAYASU and YASUHIRO KURAMITSU

  Anticancer Research April 2025, 45 (4) 1661-1666; DOI: https://doi.org/10.21873/anticanres.17547
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  Comparison of Postoperative Outcomes of Laparoscopic Versus Open Gastrectomy in Older Patients With Gastric Cancer

  TOMOHIRO TAKAHASHI, TOMOYUKI MATSUNAGA, HIROAKI SAITO, TOMOHIRO OSAKI, SADAMU TAKAHASHI, AKEMI IWAMOTO, KENJI FUKUDA, KENJIRO TANIGUCHI, HIROHIKO KURODA, TSUTOMU TAKEUCHI, KENJI SUGAMURA, KENICHI SUMI, KUNIYUKI KATANO, SHOTA SHIMIZU, YUJI SHISHIDO, KOZO MIYATANI, TERUHISA SAKAMOTO and YOSHIYUKI FUJIWARA

  Anticancer Research April 2025, 45 (4) 1667-1679; DOI: https://doi.org/10.21873/anticanres.17548
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  Significance of Systemic Inflammatory Markers as Prognostic Predictors in Stage II/III Gastric Cancer Among Older Patients

  KENJI KURODA, TAKAHIRO TOYOKAWA, GEN TSUJIO, YUICHIRO MIKI, MAMI YOSHII, HIROAKI KASASHIMA, TATSUNARI FUKUOKA, TATSURO TAMURA, MASATSUNE SHIBUTANI, SHIGERU LEE, MASAKAZU YASHIRO and KIYOSHI MAEDA

  Anticancer Research April 2025, 45 (4) 1681-1694; DOI: https://doi.org/10.21873/anticanres.17549
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  Chemotherapy Efficacy in Patients With Colorectal Cancer Experiencing Early Recurrence During or After Adjuvant Chemotherapy

  DAI OKEMOTO, TOSHIFUMI YAMAGUCHI, KANAKO SUGINO, NANAKO MATSUO, MAKOTO SANOMURA, SHIN KAMEISIHI, TORU KADONO, HIROYUKI KODAMA, HIROKI YUKAMI, ELHAM FAKHREJAHANI and HIROKI NISHIKAWA

  Anticancer Research April 2025, 45 (4) 1695-1705; DOI: https://doi.org/10.21873/anticanres.17550
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  Cardioprotective Effect of Pegfilgrastim on Chemotherapy-induced Cardiotoxicity in Preoperative Chemotherapy for Breast Cancer

  TAKAAKI FUJII, YUKO NAKAZAWA, MAYU AOKI, KEIKO TANABE, MISATO OGINO, SAYAKA OBAYASHI and KEN SHIRABE

  Anticancer Research April 2025, 45 (4) 1707-1712; DOI: https://doi.org/10.21873/anticanres.17551
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  Mid-term Combination Immunotherapy and its Effect on the Albumin–Bilirubin Score in Unresectable Hepatocellular Carcinoma

  AKIFUMI KUWANO, MASAYOSHI YADA, KOSUKE TANAKA, JUNRO TAKAHIRA, HIDEO SUZUKI and KENTA MOTOMURA

  Anticancer Research April 2025, 45 (4) 1713-1721; DOI: https://doi.org/10.21873/anticanres.17552
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  Overall Incidence of Postoperative Pancreatic Fistula After Early Drain Removal in Distal Pancreatectomy

  TERUHISA SAKAMOTO, JUN YOSHIDA, MIKIYA KISHINO, YUKI MURAKAMI, KOZO MIYATANI, YUJI SHISHIDO, KYOICHI KIHARA, MANABU YAMAMOTO, TOMOYUKI MATSUNAGA, NARUO TOKUYASU and YOSHIYUKI FUJIWARA

  Anticancer Research April 2025, 45 (4) 1723-1730; DOI: https://doi.org/10.21873/anticanres.17553
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  Neoadjuvant Chemoradiotherapy Enhances Tumor PD-L1 Expression in Pancreatic Cancer

  KANECHIKA DEN, TAKASHI MURAKAMI, RYUSEI MATSUYAMA, KENTARO MIYAKE, YUKI HOMMA, YASUHIRO YABUSHITA, RYUTARO MORI, YUKIHIKO HIROSHIMA, IKUMA KATO and ITARU ENDO

  Anticancer Research April 2025, 45 (4) 1731-1747; DOI: https://doi.org/10.21873/anticanres.17554
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  Characteristics and Mortality of Patients With Cancer Diagnosed With SARS-CoV-2 in Northern Portugal

  JOSÉ TAVEIRA-BARBOSA, TERESA GARCIA, ANA LEBRE, FILIPA FONTES, MARIANA BRANDÃO, RITA CALISTO, RUBÉN TURÉ, MARIA JOSÉ BENTO, NUNO LUNET, SAMANTHA MORAIS and LUÍSA LOPES-CONCEIÇÃO

  Anticancer Research April 2025, 45 (4) 1749-1760; DOI: https://doi.org/10.21873/anticanres.17555
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  Clinical Utilization and Infrastructure of Radiation Therapy in Korea in 2020 and 2021

  JIN-KYU KANG, WON IL JANG, MI-SOOK KIM, EUNJI KIM, HEE JIN KIM, JAESUN YOON, YOUNG-JOO SHIN, JONGWOO KIM, KUM-BAE KIM and JUNG YOUNG KIM

  Anticancer Research April 2025, 45 (4) 1761-1775; DOI: https://doi.org/10.21873/anticanres.17556
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  Splenic Angiosarcoma and Numerous Liver Metastases Presenting the Kasabach-Merritt Phenomenon

  TOSHIRO MASUDA, TORU BEPPU, YASUNORI NAGAYAMA, HIDEAKI MIYAMOTO, YOSHIHIRO KOMOHARA, ERI ODA, RYUICHI KARASHIMA, TAKASHI NAKAGAKI, YUKI ADACHI and TAKATOSHI ISHIKO

  Anticancer Research April 2025, 45 (4) 1777-1784; DOI: https://doi.org/10.21873/anticanres.17557
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  A Huge Hepatocellular Carcinoma With Major Arteriovenous Shunt Successfully Treated With Chemoembolization Plus Lenvatinib Therapy Followed by Radiotherapy

  TOSHIRO MASUDA, TORU BEPPU, HIDEAKI MIYAMOTO, YASUNORI NAGAYAMA, YOSHIYUKI FUKUGAWA, TOSHIHIKO MOTOHARA, YUKI ADACHI, ERI ODA, RYUICHI KARASHIMA, KAZUAKI YOSHIZATO and TAKATOSHI ISHIKO

  Anticancer Research April 2025, 45 (4) 1785-1792; DOI: https://doi.org/10.21873/anticanres.17558