Table of Contents

Clinical Studies

• Open Access

  Utilization and Outcomes of the 21-Gene Recurrence Score in pN2 Breast Cancer Patients

  WAQAR HAQUE, VIVEK VERMA, NIVA MANGALAMPALLI, MARY R. SCHWARTZ, E. BRIAN BUTLER, KAI SUN, DHARAMVIR JAIN, CANDY ARENTZ, AKSHAY RAMAKRISHNAN and BIN S. TEH

  Anticancer Research March 2025, 45 (3) 1055-1061; DOI: https://doi.org/10.21873/anticanres.17492
• Open Access

  Impact of Surgical Refusal on Overall Survival in Patients With Melanoma: A Comprehensive Analysis

  REED POPP, BANSI P. SAVALIYA, SWATHI R. RAIKOT, SYEDA HOORULAIN AHMED, RAMIN SHEKOUHI, JADE BOWERS, KYLE POPP, KULKAEW B. SUKNIAM, GABRIELLE KOWKABANY, PAOLA BERRIOS JIMENEZ, FATIMA MUBARAK, ESINAM P. EKPEH, SHIVAM BANSAL, SEEMA SHARAN, HARSHEEN K. MANAISE and EMMANUEL M. GABRIEL

  Anticancer Research March 2025, 45 (3) 1063-1070; DOI: https://doi.org/10.21873/anticanres.17493
• Open Access

  Outcomes of Oncologic Total Humeral Reconstruction

  LEILANI GARAYUA-CRUZ, SAMUEL E. BROIDA, MIKAELA H. SULLIVAN, MARK E. MORREY, JONATHAN D. BARLOW, JOAQUIN SANCHEZ-SOTELO and MATTHEW T. HOUDEK

  Anticancer Research March 2025, 45 (3) 1071-1075; DOI: https://doi.org/10.21873/anticanres.17494
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  A Phase II Trial of Trastuzumab Combined With Irinotecan in Patients With Advanced HER2-positive Chemotherapy-refractory Gastric Cancer (OGSG1203 HERBIS-5): Final Results

  JUNJI KAWADA, DAISUKE SAKAI, YUTAKA KIMURA, MOTOHIRO HIRAO, KAZUHIRO NISHIKAWA, NAOTOSHI SUGIMOTO, YOSHIO OKA, SHUNJI ENDO, YUTAKA ISOZAKI, JIN MATSUYAMA, RYOHEI KAWABATA, TOMONO KAWASE, KAZUMASA FUJITANI, YUKINORI KUROKAWA, HISATO KAWAKAMI, TOSHIO SHIMOKAWA, TAROH SATOH and Osaka Gastrointestinal Cancer Chemotherapy Study Group (OGSG)

  Anticancer Research March 2025, 45 (3) 1077-1085; DOI: https://doi.org/10.21873/anticanres.17495
• Open Access

  Mismatch Between Preoperative MRI Findings and Postoperative Histological Results in the Treatment of Tenosynovial Giant Cell Tumor

  JOHANNES NEUGEBAUER, PHILLIP BLUM, ALEXANDER KEILER, MARKUS SÜß, PATRICK REINBACHER, MARKUS NEUBAUER, GIANPAOLO LEONE, MARKO BERGOVEC and DIETMAR DAMMERER

  Anticancer Research March 2025, 45 (3) 1087-1096; DOI: https://doi.org/10.21873/anticanres.17496
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  Male Breast Cancer: A Single Institutional Clinicopathological Profiling

  SHUBHA DE SARKAR, SOIRINDHRI BANERJEE, AYDEN ISMAIL, AVENIE MAVADIA, SUNYOUNG CHOI, ARUNI GHOSE and STERGIOS BOUSSIOS

  Anticancer Research March 2025, 45 (3) 1097-1104; DOI: https://doi.org/10.21873/anticanres.17497
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  Efficacy of Molecular-targeted Agents in Vertebral Metastasis Management in Non-small Cell Lung Cancer

  MIDORI YUI, SATOAKI NAKAMURA, YUHEI KOIKE, KAZUKI HIROTA, KEN YOSHIDA, ASAMI YOSHIDA, KENICHI UEDA, KEN SHIGEYAMA, HIDEKI TAKEGAWA, YUSUKE ANETAI, MASAAKI PAKU, TAKAYASU KURATA, HIDEYA YAMAZAKI and NOBORU TANIGAWA

  Anticancer Research March 2025, 45 (3) 1105-1115; DOI: https://doi.org/10.21873/anticanres.17498
• Open Access

  Efficacy of Lenvatinib and Atezolizumab Bevacizumab Combination Therapy in Patients With Combined Hepatocellular-cholangiocarcinoma

  NORIKAZU TANABE, ISSEI SAEKI, KENJI YAMAOKA, TOMOKAZU KAWAOKA, TETSU TOMONARI, JOJI TANI, TAKESHI TERASHIMA, YUSUKE KAWAMURA, SHIRO OKA, TETSUJI TAKAYAMA, HIDEKI KOBARA, TARO YAMASHITA, NORIO AKUTA, TAKAHIRO YAMASAKI and TARO TAKAMI

  Anticancer Research March 2025, 45 (3) 1117-1125; DOI: https://doi.org/10.21873/anticanres.17499
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  Stereotactic Body Radiotherapy Using CyberKnife for Metastatic Liver Tumors: A Single-center Retrospective Study

  YASUHIRO RYUNO, TAKANORI ABE, KEITA TSUKAHARA, JUN WATANABE, MISAKI IINO, SATOSHI SAITO, TOMOMI AOSHIKA, TOMOHIRO OHTA, MITSUNOBU IGARI, RYUTA HIRAI, YU KUMAZAKI, SHIN-EI NODA and SHINGO KATO

  Anticancer Research March 2025, 45 (3) 1127-1136; DOI: https://doi.org/10.21873/anticanres.17500
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  Genomic Profiling of Small Cell Neuroendocrine Prostate Cancer and its Implications for Targeted Therapies

  JUNICHIRO HIRATA, TAKUTO HARA, NAOE JIMBO, HIDETO UEKI, YASUYOSHI OKAMURA, YUKARI BANDO, KOTARO SUZUKI, TOMOAKI TERAKAWA, JUN TEISHIMA, KOJI CHIBA and HIDEAKI MIYAKE

  Anticancer Research March 2025, 45 (3) 1137-1147; DOI: https://doi.org/10.21873/anticanres.17501
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  Radiotherapy for Bone Metastases in Patients With Excellent Performance Status: Patterns of Care and Prognostic Factors for Survival

  CARSTEN NIEDER, ELLINOR C. HAUKLAND, LUKA STANISAVLJEVIC and BÅRD MANNSÅKER

  Anticancer Research March 2025, 45 (3) 1149-1158; DOI: https://doi.org/10.21873/anticanres.17502
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  Clinical Outcomes of Patients Receiving Stereotactic Body Radiotherapy Dose De-escalation for Hepatocellular Carcinoma at the Hepatic Hilum

  TAKESHI FUJISAWA, HIDEHIRO HOJO, MASAKI NAKAMURA, KENJI MAKITA, HIDENARI HIRATA, HIDEKAZU OYOSHI, KENTO TOMIZAWA, YUZHENG ZHOU, KEIKO FUKUSHI, MASAFUMI IKEDA and SADAMOTO ZENDA

  Anticancer Research March 2025, 45 (3) 1159-1169; DOI: https://doi.org/10.21873/anticanres.17503
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  Proprotein Convertase Subtilisin/Kexin Type 9 Induction in Hypercholesterinemic Patients With Primary and Metastatic Liver Tumors

  THOMAS S. WEISS and CHRISTA BUECHLER

  Anticancer Research March 2025, 45 (3) 1171-1180; DOI: https://doi.org/10.21873/anticanres.17504
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  Real-world Outcomes in Recurrent/Metastatic Squamous Cell Carcinoma of Head and Neck With Nivolumab: Galician Study

  LETICIA IGLESIAS, ROCÍO VÍLCHEZ, SANTIAGO AGUÍN, RAMÓN GARCÍA, CAROLINA PENA, ALBERTO CARRAL, GERARDO HUIDOBRO, AUREA MOLINA, JESÚS GARCÍA GÓMEZ, MARTA COVELA, MARINHA COSTA and ANA MEDINA

  Anticancer Research March 2025, 45 (3) 1181-1191; DOI: https://doi.org/10.21873/anticanres.17505
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  Impact of Postoperative Therapy on Survival Outcomes in Non-small Cell Lung Cancer Patients With Microscopic Residual Disease

  HIROKI WATANABE, SHOTA NAKAMURA, YOSHITO IMAMURA, SHOJI OKADO, YUJI NOMATA, YUTA KAWASUMI, YUKA KADOMATSU, HARUSHI UENO, TAKETO KATO, TETSUYA MIZUNO and TOYOFUMI FENGSHI CHEN-YOSHIKAWA

  Anticancer Research March 2025, 45 (3) 1193-1204; DOI: https://doi.org/10.21873/anticanres.17506
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  Clinical Significance of Residual Lymph Node Metastasis in Predicting Recurrence After Preoperative Chemotherapy and Surgery for Gastric Cancer

  KEISUKE KOMORI, TAKANOBU YAMADA, SHUJI ANDO, SHINSUKE NAGASAWA, KYOHEI KANEMATSU, JUNYA MORITA, MIE TANABE, YUTA NAKAYAMA, YASUSHI RINO, AYA SAITO, TAKASHI OGATA and TAKASHI OSHIMA

  Anticancer Research March 2025, 45 (3) 1205-1214; DOI: https://doi.org/10.21873/anticanres.17507
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  Perioperative and Oncologic Outcomes of Robot-assisted Versus Laparoscopic Radical Cystectomy in Patients With Bladder Cancer

  NORIYA YAMAGUCHI, SHUICHI MORIZANE, HIROSHI YAMANE, RYUTARO SHIMIZU, RYOMA NISHIKAWA, YUSUKE KIMURA, KATSUYA HIKITA, KUNIYASU MURAOKA, HIROFUMI ONO, KOJI ONO, MASASHI HONDA and ATSUSHI TAKENAKA

  Anticancer Research March 2025, 45 (3) 1215-1224; DOI: https://doi.org/10.21873/anticanres.17508
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  Prognostic Relationship Between the Cachexia Index and Osteopenia in Patients With Pancreatic Cancer

  TERUHISA SAKAMOTO, MIKIYA KISHINO, YUKI MURAKAMI, KOZO MIYATANI, YUJI SHISHIDO, KYOICHI KIHARA, TOMOYUKI MATSUNAGA, MANABU YAMAMOTO, NARUO TOKUYASU and YOSHIYUKI FUJIWARA

  Anticancer Research March 2025, 45 (3) 1225-1231; DOI: https://doi.org/10.21873/anticanres.17509
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  Oncologic Relevance and Anal Preservation Potential of Transanal Total Mesorectal Excision for Rectal Cancer Invading Adjacent Organs

  MASAHIKO SUGIYAMA, YUTA KASAGI, RENA YOKOMIZO, MUNEHIDE TERASHI, EMI OONISHI, TAICHIRO NAGAI, NAOMICHI KOGA, TOMONARI SHIMAGAKI, TAKAHIRO TOMINO, AYAKO IWANAGA, YASUE KIMURA, KEISHI SUGIMACHI and MASARU MORITA

  Anticancer Research March 2025, 45 (3) 1233-1239; DOI: https://doi.org/10.21873/anticanres.17510
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  Urethral Visualization Using Near-infrared Light Observation During Transanal/Perineal Total Mesorectal Excision

  KEISUKE GOTO, SHUNJIN RYU, YUTA IMAIZUMI, SOTARO IWAUCHI, TAKEHIRO KOBAYASHI, RYUSUKE ITO and YUKIO NAKABAYASHI

  Anticancer Research March 2025, 45 (3) 1241-1249; DOI: https://doi.org/10.21873/anticanres.17511
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  The CONUT Score Can Predict the Prognosis of Gastric Cancer Patients After Curative Treatment

  RYUKI ESASHI, TORU AOYAMA, SOSUKE YAMAMOTO, YUKIO MAEZAWA, ITARU HASHIMOTO, KEISUKE KAZAMA, JYUNYA MORITA, SHINNOSUKE KAWAHARA, KAZUKI OTANI, KEISUKE KOMORI, TETSUSHI ISHIGURO, SUGURU NUKADA, KIYOKO SHIMADA, AYAKO TAMAGAWA, AYA SAITO and NORIO YUKAWA

  Anticancer Research March 2025, 45 (3) 1251-1260; DOI: https://doi.org/10.21873/anticanres.17512
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  Tailoring Neoadjuvant Therapy for Rectal Cancer: A Single-center Study of Local Recurrence Patterns

  RYOHEI SHOJI, FUMINORI TERAISHI, YOSHITAKA KONDO, YUSUKE YOSHIDA, NOBUHIKO KANAYA, YUKI MATSUMI, KUNITOSHI SHIGEYASU, SHUNSUKE KAGAWA and TOSHIYOSHI FUJIWARA

  Anticancer Research March 2025, 45 (3) 1261-1271; DOI: https://doi.org/10.21873/anticanres.17513
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  ¹⁸F-Fluorocholine PET/CT as an Imaging Biomarker in Patients With Hepatocellular Carcinoma Receiving Atezolizumab Plus Bevacizumab

  WONSEOK WHI, HYUNJONG LEE, JUNG YONG HONG, WONSEOK KANG, YOUNG SEOK CHO, SEUNG HWAN MOON, JOON YOUNG CHOI, KYUNG-HAN LEE and SEUNG HYUP HYUN

  Anticancer Research March 2025, 45 (3) 1273-1280; DOI: https://doi.org/10.21873/anticanres.17514
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  Safety and Outcomes of Intraoperative Ventriculoperitoneal Shunt Clamping During Robotic-assisted Radical Prostatectomy: Retrospective Cohort Analysis

  JHE-YUAN HSU, HSIEN-CHE OU, YEN-CHUAN OU, YI-SHENG LIN, LI-HUA HUANG, WEI-CHUN WENG, CHAO-YU HSU and MIN-CHE TUNG

  Anticancer Research March 2025, 45 (3) 1281-1289; DOI: https://doi.org/10.21873/anticanres.17515
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  Short-term Safety of Robot-assisted Rectal Surgery in Patients Aged ≥75 Years: A Single-center Retrospective Study

  FUMINORI TERAISHI, YUSUKE YOSHIDA, RYOHEI SHOJI, NOBUHIKO KANAYA, YUKI MATSUMI, KUNITOSHI SHIGEYASU, YOSHITAKA KONDO, SHUNSUKE KAGAWA and TOSHIYOSHI FUJIWARA

  Anticancer Research March 2025, 45 (3) 1291-1299; DOI: https://doi.org/10.21873/anticanres.17516