Anticancer Research: 45 (12)

December 2025; Volume 45,Issue 12

Review

Open Access
Dicycloplatin, a Novel Analog of Cisplatin and Carboplatin, May Provide Therapeutic Advancement in Cancer Chemotherapy
BING-XUE YAN, XIANGTAO LIU, CHUANXI HAO, YI GUO, XUQING YANG and JING JIE YU

Anticancer Research December 2025, 45 (12) 5247-5254; DOI: https://doi.org/10.21873/anticanres.17865

Experimental Studies

Open Access
Inhibition of Cholesterol Transport from Lysosomes by Itraconazole Repolarizes Tumor-associated Macrophages to Anti-tumor M1 type
YUMI TAKIMOTO, HIROSHI TSUBAMOTO, YUSHI TSUBAMOTO, ATSUSHI TAMURA, ROZE TANIGUCHI, KAZUKO SAKATA, TOMOKO UEDA, SACHIYO NARITA, YU WAKIMOTO and SEIJI MABUCHI

Anticancer Research December 2025, 45 (12) 5255-5266; DOI: https://doi.org/10.21873/anticanres.17866
Open Access
RPA1, RFC1, and POLE Expression in Clear Cell Renal Cell Carcinoma: Immune and Clinical Relevance
MICHAŁ GOLA, JACEK KIEŻUN, BARTŁOMIEJ EMIL KRAZIŃSKI, HANNA MAJEWSKA, ALEKSANDRA SEJDA and JANUSZ GODLEWSKI

Anticancer Research December 2025, 45 (12) 5267-5286; DOI: https://doi.org/10.21873/anticanres.17867
Open Access
Inhibition of Small-cell Lung Cancer Angiogenesis by Irinotecan Metronomic Chemotherapy and Irinotecan Plus Everolimus
YOSHIHIRO AMANO, RYOSUKE TANINO, RONG SUN, YUKARI TSUBATA, TAKESHI ISOBE and TAMIO OKIMOTO

Anticancer Research December 2025, 45 (12) 5287-5297; DOI: https://doi.org/10.21873/anticanres.17868
Open Access
Andrographolide Induces ROS-dependent Apoptosis and Suppresses STAT3 Phosphorylation in Primary Effusion Lymphoma Cells
ITNARIN MONGKON, RYUSHO KARIYA, PHORUTAI PEARNGAM, NUTSARA SETTHA, KRITTAMATE SAISUWAN, PIYANARD BOONNATE, GUNYA SITTITHUMCHAREE, KULTHIDA VAETEEWOOTTACHARN, RUNGNAPHA SAEENG and SEIJI OKADA

Anticancer Research December 2025, 45 (12) 5299-5311; DOI: https://doi.org/10.21873/anticanres.17869
Open Access
The Combination of Recombinant Methioninase and Low-dose Chloroquine Selectively Eradicates Colon-Cancer Cells Without Apparent Toxicity on Co-cultured Normal Fibroblasts
JINSOO KIM, QINGHONG HAN, SHUKUAN LI, BYUNG MO KANG, KOHEI MIZUTA, YOHEI ASANO, YUTA MIYASHI, MICHAEL BOUVET and ROBERT M. HOFFMAN

Anticancer Research December 2025, 45 (12) 5313-5320; DOI: https://doi.org/10.21873/anticanres.17870
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NSUN7 Suppression Reduces Metastatic Potential and Restores Sensitivity to 4-OH Tamoxifen in Resistant MCF-7 Cells
SANA MAHMOOD, ANDREI V. CHERNOV, SEHRISH KHAN, RAMAMURTHY CHITTETI, SALMMA SALAMAH SALIHAH, SOHAIL A. QURESHI, HEMAL H. PATEL and ASMA GUL

Anticancer Research December 2025, 45 (12) 5321-5339; DOI: https://doi.org/10.21873/anticanres.17871
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Co-expression of PD1/PD-L1 on Tumor Cells Is Involved in the Regulation of Cell Proliferation
YASUNARI NAGASAKI, HIROMICHI YAMANE, MASAMI TAKEYAMA, NOBUAKI OCHI, AYAKA MIMURA, YOKO KOSAKA, NARUHIKO ICHIYAMA, TATSUYUKI KAWAHARA, HIDEKAZU NAKANISHI, AKIO HIRAKI and NAGIO TAKIGAWA

Anticancer Research December 2025, 45 (12) 5341-5350; DOI: https://doi.org/10.21873/anticanres.17872
Open Access
Leveraging Genome-wide Association Studies to Identify Pathogenic Variants for Breast Cancer Among Multiple Continents
PUTRI PERMATA SUKA ADMANEGARA, RISTA YULIANTI, DESTI RAHMAWATI, SISKA WIDIASTUTI, WIRAWAN ADIKUSUMA, BRILLIANT CITRA WIRASHADA, DANANG PRASETYANING AMUKTI, DARMAWI DARMAWI, BAIK HENI RISPAWATI, BENNI ISKANDAR, ROCKIE CHONG, ILKER ATES and LALU MUHAMMAD IRHAM

Anticancer Research December 2025, 45 (12) 5351-5367; DOI: https://doi.org/10.21873/anticanres.17873
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Potential Role of Tumor-derived MIF in B-Cell Antigen Presentation in Lung Adenocarcinoma: Single-cell and TCGA Analyses
FIROZ AHMED and SHAWEZ KHAN

Anticancer Research December 2025, 45 (12) 5369-5387; DOI: https://doi.org/10.21873/anticanres.17874
Open Access
Selective Synergy of the Combination of Recombinant Methioninase With Cisplatinum and Ivermectin Which Eradicates Lung-Cancer Cells but Has No Synergy and Limited Effect on Normal Fibroblasts
YOHEI ASANO, QINGHONG HAN, SHUKUAN LI, KOHEI MIZUTA, BYUNG MO KANG, JIN SOO KIM, YUTA MIYASHI, NORIO YAMAMOTO, KATSUHIRO HAYASHI, HIROAKI KIMURA, SHINJI MIWA, KENTARO IGARASHI, TAKASHI HIGUCHI, SEI MORINAGA, HIROYUKI TSUCHIYA, SATORU DEMURA and ROBERT M. HOFFMAN

Anticancer Research December 2025, 45 (12) 5389-5398; DOI: https://doi.org/10.21873/anticanres.17875
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Growth Suppression and Selective Disruption of F-Actin by α-Santalol in Human Melanoma Cells
RITESH CHANDRASEKARAN, MICHAEL L. LU, CHANDRADHAR DWIVEDI and AJAY BOMMAREDDY

Anticancer Research December 2025, 45 (12) 5399-5407; DOI: https://doi.org/10.21873/anticanres.17876
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Leucine-rich Repeat-containing 15 as a Potential Marker and Therapeutic Target in Cervical Cancer
THI HAI LY DAO, KEIICHIRO NAKAMURA, KAZUHIRO OKAMOTO, THUY HA VU, ERIKO ETO and HISASHI MASUYAMA

Anticancer Research December 2025, 45 (12) 5409-5421; DOI: https://doi.org/10.21873/anticanres.17877
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Piperlongumine Induces Apoptosis and Autophagy via the MAPK/NK-κB Pathway in Human Breast Cancer Cells
YUN-SEO JANG, SU-JI JEON, SANG-WOO LEE, SU-A LEE, HUI-JIN JANG, SOO-HYUN JUNG, MYEON-SIK YANG, SANG-KI KIM, BYUNG-KWON PARK, YOUNG-SEOK PARK, BYEONG-SOO KIM and JI-YOUN JUNG

Anticancer Research December 2025, 45 (12) 5423-5434; DOI: https://doi.org/10.21873/anticanres.17878
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Down-regulation of ACSM3 Promotes Tumorigenesis in Breast Cancer
HONG-BEUM KIM, SEONG-HUN KIM, HEE-JEONG LEE and SANG-GON PARK

Anticancer Research December 2025, 45 (12) 5435-5443; DOI: https://doi.org/10.21873/anticanres.17879
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AXL Transcriptionally Up-regulates ISG15 Expression to Mediate Cell Proliferation in Non-small-cell Lung Cancer Cells
WEI-YI LEE, SHIAO-LIN TUNG, SHUANG-EN CHUANG, SHENG-CHIEH LIN, CHIH-CHIU CHIANG, I-TA LU and TE-HSUAN JANG

Anticancer Research December 2025, 45 (12) 5445-5455; DOI: https://doi.org/10.21873/anticanres.17880
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Bis-type Triaziquone Induces PARP1-mediated Cell Death in Human NPC/HK1 Nasopharyngeal Carcinoma Cells
CHIH-CHUN WANG, TZER-ZEN HWANG, MENG-CHE HSIEH, TZU-HAN KAO, YINGXIAO LI and YU-YAN LAN

Anticancer Research December 2025, 45 (12) 5457-5464; DOI: https://doi.org/10.21873/anticanres.17881
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Homochlorcyclizine Dihydrochloride Inhibits Hepatocellular Carcinoma Progression and Cancer Stem Cell Properties
JIAYI WU, XINZHU FU, SHIYUAN CHANG and WEIJUN SU

Anticancer Research December 2025, 45 (12) 5465-5475; DOI: https://doi.org/10.21873/anticanres.17882
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Ibrutinib Inhibits Tumor Progression, Alleviates Pain, and Protects the Tibia in a Bone Metastasis Model of Lung Cancer
RONG-GUANG LUO, XIAN-BING XIE, YUAN-YUAN ZHANG, YUAN-QIAO HE and QUN TANG

Anticancer Research December 2025, 45 (12) 5477-5490; DOI: https://doi.org/10.21873/anticanres.17883

Clinical Studies

Open Access
Uniformity Between Serological Biomarker Test, Esophago-gastro-duodenoscopy and Biopsy Histology in Triage of Upper Abdominal Symptoms in Gastroscopy Referral Patients
OLLI-PEKKA KOIVUROVA, TIMO BLOMSTER, MATTI ESKELINEN, PENTTI SIPPONEN, PANU HENDOLIN, OSMO SUOVANIEMI, JANNE MARTIKAINEN, KARI SYRJÄNEN and ILKKA VOHLONEN

Anticancer Research December 2025, 45 (12) 5491-5501; DOI: https://doi.org/10.21873/anticanres.17884
Open Access
Comparative Analysis of FDG-PET Versus CT/MRI in Staging and Management of Advanced-stage Cervical Cancer
MAHWISH NAYAB, MOSTAFA ELNAGGAR, VIREN ASHER, ANISH BALI, SUMMI ABDUL, MOJCA PERSIC and ANDREW PHILLIPS

Anticancer Research December 2025, 45 (12) 5503-5511; DOI: https://doi.org/10.21873/anticanres.17885
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Neoadjuvant Radiochemotherapy for Locally Advanced Rectal Cancer: A Single-institutional Real-world Study
RALPH MUECKE, KHASHAYAR FAKHRIAN, ROBERT GOSENHEIMER, VOLKER SCHMITZ, CHRISTOPH SCHULZ, PER KNOESS, CHRISTINA HARVEY, CHRISTIANE MUECKE, MATTHIAS BUSSMANN, ARNOLD NISSEN and MARKUS PASCHOLD

Anticancer Research December 2025, 45 (12) 5513-5521; DOI: https://doi.org/10.21873/anticanres.17886
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Surgical and Oncologic Outcomes in Uterine Carcinosarcoma: A Retrospective Cohort Analysis
RAHUL CHATTERJEE, ALEXANDRA COCKING, MOHAMMAD EDDAMA, DESIREE KOLOMAINEN, GAUTAM MEHRA, RAHUL NATH and AHMAD SAYASNEH

Anticancer Research December 2025, 45 (12) 5523-5531; DOI: https://doi.org/10.21873/anticanres.17887
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Impact of the Introduction of the S3 Guideline on the Management of Primary Endometrial Cancer: A Comparative Analysis of Cancer Registry Data from Hamburg (2014-2022)
ANNEMARIE SCHULTZ, FREDERIK PETERS, NIKLAS JOBST and GERHARD GEBAUER

Anticancer Research December 2025, 45 (12) 5533-5542; DOI: https://doi.org/10.21873/anticanres.17888
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Prognostic Value of Tertiary Lymphoid Structures in Epithelial Ovarian Carcinoma
TAKEHIRO NAKAO, KENICHI HARANO, MASASHI WAKABAYASHI, TETSURO TAKI, REIKO WATANABE, HIROSHI TANABE and TORU MUKOHARA

Anticancer Research December 2025, 45 (12) 5543-5555; DOI: https://doi.org/10.21873/anticanres.17889
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Feasibility of Minimally Invasive Surgery for Locally Advanced Gastric Cancer After Neoadjuvant Chemotherapy: A Four-arm Comparative Study
TARO IKEDA, SHINGO KANAJI, NAOKI URAKAWA, HITOSHI HARADA, YUTAKA SUGITA, MASAYUKI ANDO, YASUFUMI KOTERAZAWA, TOMOAKI AOKI, YASUNORI OTOWA, HIRONOBU GOTO, HIROSHI HASEGAWA, KIMIHIRO YAMASHITA, TAKERU MATSUDA and YOSHIHIRO KAKEJI

Anticancer Research December 2025, 45 (12) 5557-5566; DOI: https://doi.org/10.21873/anticanres.17890
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Prognostic Significance of Preoperative Peripheral Circulating Eosinophils in Patients who Underwent Esophagectomy for Esophageal Cancer
KEITA TAKAHASHI, MASAMI YUDA, YOSHITAKA ISHIKAWA, TAKANORI KUROGOCHI, AKIRA MATSUMOTO, TAKAHIRO MASUDA, NAOKO FUKUSHIMA, KAZUTO TSUBOI, FUMIAKI YANO and KEN ETO

Anticancer Research December 2025, 45 (12) 5567-5577; DOI: https://doi.org/10.21873/anticanres.17891
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Impact of Baseline Body Mass Index on Immunotherapy Outcomes in Patients With Non-small-cell Lung Cancer
DANIEL KREJČÍ, ADAM ŠUBRT, PETR OPÁLKA, JANA KREJČÍ, MONIKA ŠIBALOVÁ, MARTIN SVATOŇ, MILOSLAV PÁLA, PETRA TESAŘOVÁ and NORBERT PAUK

Anticancer Research December 2025, 45 (12) 5579-5586; DOI: https://doi.org/10.21873/anticanres.17892
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Effect of Tissue Sample Type on The Evaluation of PD-L1 (SP142) Expression in Breast Cancer
TAKESHI USUI, MASAFUMI SHIMODA, KAORI ABE, NANAE MASUNAGA, MASAMI TSUKABE, TETSUHIRO YOSHINAMI, YOSHIAKI SOTA, TOMOHIRO MIYAKE, TOMONORI TANEI and KENZO SHIMAZU

Anticancer Research December 2025, 45 (12) 5587-5594; DOI: https://doi.org/10.21873/anticanres.17893
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Should Upfront Therapy With Androgen Receptor Signaling Inhibitors Be Used in All Japanese Patients With Metastatic Castration-sensitive Prostate Cancer?
KENTA ONISHI, YASUSHI NAKAI, MAKITO MIYAKE, YOSHIAKI MATSUMURA, MIKIKO ONISHI, KEIICHI SAKAMOTO, SHUNSUKE HAJIKANO, YUSUKE IEMURA, MASAKI HARAMOTO, FUMISATO MAESAKA, SHUYA HIRAO, TAKANORI YOSHIDA, KUNIAKI INOUE, TOSHIHISA SAKA, TAKASHI IWAMOTO, YUKINARI HOSOKAWA, KOTA IIDA, YOSHITAKA ITAMI, KIYOHIDE FUJIMOTO and NOBUMICHI TANAKA

Anticancer Research December 2025, 45 (12) 5595-5607; DOI: https://doi.org/10.21873/anticanres.17894
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Efficacy and Safety of Oral 5-FU Derivatives After Progression of HR⁺/HER2⁻ Metastatic Breast Cancer on CDK4/6 Inhibitor
YUMIKO KOI, WAKAKO TAJIRI, JUNJI KAWASAKI, SAYURI AKIYOSHI, HIDEKI IJICHI, YOSHIAKI NAKAMURA, CHINAMI KOGA and ERIKO TOKUNAGA

Anticancer Research December 2025, 45 (12) 5609-5618; DOI: https://doi.org/10.21873/anticanres.17895
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Postoperative Complications, Including Minor Complications, Worsen Prognosis After Laparoscopic Distal Gastrectomy for Gastric Cancer
YUMA EBIHARA, NORIAKI KYOGOKU, HIRONOBU TAKANO, HIDEYUKI WADA, TAKEO NITTA, DAISUKE SAIKAWA, YOSHIYUKI YAMAMURA, MINORU TAKADA, TOSHIAKI SHICHINOHE and SATOSHI HIRANO

Anticancer Research December 2025, 45 (12) 5619-5631; DOI: https://doi.org/10.21873/anticanres.17896
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Prognostic Factors in Non-small Cell Lung Cancer Patients Treated With Immune Checkpoint Inhibitors
YUTAKA TAKAHARA, RYUDAI ABE, SUMITO NAGAE, TAKUYA TANAKA, YOKO ISHIGE, IKUYO SHIONOYA, KOUICHI YAMAMURA, MASAFUMI NOJIRI and MASAHARU IGUCHI

Anticancer Research December 2025, 45 (12) 5633-5644; DOI: https://doi.org/10.21873/anticanres.17897
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Renal Function With Enfortumab Vedotin in Metastatic Urothelial Carcinoma: A Multicenter Retrospective Study in Japan
YUKI KOBARI, JUNPEI IIZUKA, HANAE KONDO, MAKIKO ICHIOKA, SHUN WATANABE, KAZUTAKA NAKAMURA, YUKI NEMOTO, TOSHIHIDE HORIUCHI, SHINSUKE MIZOGUCHI, KAZUHIKO YOSHIDA, HIROAKI SHIMMURA, YASUNOBU HASHIMOTO, TSUNENORI KONDO, HIROSHI KOBAYASHI and TOSHIO TAKAGI

Anticancer Research December 2025, 45 (12) 5645-5654; DOI: https://doi.org/10.21873/anticanres.17898
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Impact of Emphysema Severity on Clinicopathological and Molecular Features in Non–small Cell Lung Cancer
YOSHIYUKI YASUURA, TETSUKAN WOO, SHOMA TANAKA, HARUHIKO MASUDA, YOHEI KAMEDA, KENJI INAFUKU and AYA SAITO

Anticancer Research December 2025, 45 (12) 5655-5666; DOI: https://doi.org/10.21873/anticanres.17899
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Clinical Utility of the Preoperative Cachexia Index in Patients Undergoing Curative Gastrectomy for Gastric Cancer
ITARU HASHIMOTO, YUTA NAKAYAMA, MIE TANABE, JUNYA MORITA, SHINSUKE NAGASAWA, YUKIO MAEZAWA, KYOHEI KANEMATSU, TORU AOYAMA, TAKANOBU YAMADA, NORIO YUKAWA, AYA SAITO, TAKASHI OGATA and TAKASHI OSHIMA

Anticancer Research December 2025, 45 (12) 5667-5674; DOI: https://doi.org/10.21873/anticanres.17900
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Genomic Correlations for Clinical Outcomes in HER2-positive Advanced Gastric Cancer Treated Using Trastuzumab-based Therapy
SUN YOUNG LEE, JAEWON HYUNG, HYUNG-DON KIM, HYUNGEUN LEE, MEESUN MOON, YOUNG SOO PARK and MIN-HEE RYU

Anticancer Research December 2025, 45 (12) 5675-5688; DOI: https://doi.org/10.21873/anticanres.17901
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Precise Anatomical Resection of the Left Lateral Section Using Extrahepatic Glissonean Approach and Fluorescence Guidance
NOBUHISA TANIOKA, SATORU SEO, YASUHIRO KAWANISHI, KAZUNE FUJISAWA, MASAYA MUNEKAGE, MAEDA HIROMICHI and HIROYUKI KITAGAWA

Anticancer Research December 2025, 45 (12) 5689-5695; DOI: https://doi.org/10.21873/anticanres.17902
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Prior Radiotherapy Improves Progression-free Survival in Patients With Advanced Hepatocellular Carcinoma Treated With Tremelimumab–Durvalumab
AKIFUMI KUWANO, KOSUKE TANAKA, TAIKAN HAMAMOTO, KAZUKI KUROSAKA, HIDEO SUZUKI, MASAYOSHI YADA, YOSHIHIRO OHISHI, TOMONARI SASAKI and KENTA MOTOMURA

Anticancer Research December 2025, 45 (12) 5697-5708; DOI: https://doi.org/10.21873/anticanres.17903
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Optimizing Biopsy Decisions in PI-RADS 3-4 Lesions: Integrating PSA-derived Biomarkers to Reduce Unnecessary Procedures
JEN-HAO KUO, YIN-CHIEN OU, CHE-YUAN HU, KUAN-YU WU, CHAN-JUNG LIU, ZE-HONG LU, HAU-CHERN JAN, KUN-CHE LIN, YI-CHIA HSIEH, CHIEN-HUI OU and YUH-SHYAN TSAI

Anticancer Research December 2025, 45 (12) 5709-5720; DOI: https://doi.org/10.21873/anticanres.17904
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Surgical Outcomes and Postoperative Changes in Nutritional Indexes and Sarcopenia Markers in Oldest-old Patients With Resected Biliary Tract Cancer: A Retrospective Cohort Study
MASASHI UTSUMI, MASARU INAGAKI, KOJI KITADA, NAOYUKI TOKUNAGA, NAOKI ONODA, KOKI OMOTO, RYUSEI TAKAHASHI, HIROKI OKABAYASHI, RYOSUKE HAMANO, HIDEAKI MIYASO, FUMINORI TERAISHI, YOSUKE TSUNEMITSU and SHINYA OTSUKA

Anticancer Research December 2025, 45 (12) 5721-5734; DOI: https://doi.org/10.21873/anticanres.17905
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Determining Candidate D-dimer Thresholds for Lower-extremity Ultrasound in Monitoring Deep Vein Thrombosis in Patients With Gastric Cancer Receiving Ramucirumab
SHOYA TAKENAKA, MICHIO KIMURA, MINA IWAI and EISEKI USAMI

Anticancer Research December 2025, 45 (12) 5735-5741; DOI: https://doi.org/10.21873/anticanres.17906
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Exploratory Analysis of Dunning–Kruger Effect Among Oncologists Managing Prostatic Adenocarcinoma Candidates for Radionuclide Therapy
DANIELA SAMBATARO, VITTORIO GEBBIA, FABRIZIO SCRIMA, NICOLÒ BORSELLINO, RENATO COSTA, DEMETRIO ARICÒ, ROSARIO PARATORE, GIUSEPPA SCANDURRA, VINCENZO SERRETTA, ANTONIO DAIDONE and MARIA ROSARIA VALERIO

Anticancer Research December 2025, 45 (12) 5743-5751; DOI: https://doi.org/10.21873/anticanres.17907
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Cytoreductive Surgery With or Without Intraperitoneal Chemotherapy for Peritoneal Spread from Appendiceal Neoplasms and Cancers
JUNG WOOK SUH, HWAN NAMGUNG, JAE WON JO, SUNG CHUL LEE and DONG-GUK PARK

Anticancer Research December 2025, 45 (12) 5753-5763; DOI: https://doi.org/10.21873/anticanres.17908
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Pulmonary Emphysema Assessed by the Goddard Score Predicts Outcomes After Hepatic Resection for Colorectal Liver Metastases
KENEI FURUKAWA, KOICHIRO HARUKI, YOSIHIRO SHIRAI, SHINJI ONDA, MASASHI TSUNEMATSU, MICHINORI MATSUMOTO, TADASHI UWAGAWA, TOMOHIKO TANIAI, MITSURU YANAGAKI and TORU IKEGAMI

Anticancer Research December 2025, 45 (12) 5765-5772; DOI: https://doi.org/10.21873/anticanres.17909
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Efficacy of Platinum-based Chemotherapy for Platinum-sensitive Recurrent Ovarian Cancer During PARP Inhibitor Treatment: A Multicenter Retrospective Study
ERIKO TAKATORI, TADAHIRO SHOJI, AMI JO, MIKU MUSASHI, SHUNSUKE TATSUKI, NANAKO JONAI, YOHEI CHIBA, SHO SATO, YOSHITAKA KAIDO, TAKAYUKI NAGASAWA, MASAHIRO KAGABU, FUMIAKI TAKAHASHI, TAKESHI AIDA and TSUKASA BABA

Anticancer Research December 2025, 45 (12) 5773-5783; DOI: https://doi.org/10.21873/anticanres.17910

Case Reports

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Good Quality 66.7% 5-year Overall Survival in Terminal Lung Cancer Patients Treated With Mifepristone
JEROME H. CHECK, DIANE L. CHECK and CARRIE WILSON

Anticancer Research December 2025, 45 (12) 5785-5798; DOI: https://doi.org/10.21873/anticanres.17911
Open Access
Rapid Eradication of Extensive Spinal Metastases in a Prostate-Cancer Patient Taking Androgen-deprivation Therapy, Chemotherapy, and Oral Recombinant Methioninase on a Low-Methionine Diet
YOHEI ASANO, QINGHONG HAN, SHUKUAN LI, TOSHIHIKO SATO, CHIHIRO HOZUMI, BYUNG MO KANG, JIN SOO KIM, YUTA MIYASHI, NORIO YAMAMOTO, KATSUHIRO HAYASHI, HIROAKI KIMURA, SHINJI MIWA, KENTARO IGARASHI, TAKASHI HIGUCHI, SEI MORINAGA, HIROYUKI TSUCHIYA, SATORU DEMURA and ROBERT M. HOFFMAN

Anticancer Research December 2025, 45 (12) 5799-5805; DOI: https://doi.org/10.21873/anticanres.17912
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Carbon-ion Radiotherapy for Hepatocellular Cancer Arising in Transplanted Liver Tissue
KAZUHIKO HAYASHI, OSAMU SUZUKI, KOJI ICHISE, HIROFUMI UCHIDA, FUMIKO NAGANO, AZUSA HASEGAWA, SHINICHI SHIMIZU, JIRO FUJIMOTO and KAZUHIKO OGAWA

Anticancer Research December 2025, 45 (12) 5807-5812; DOI: https://doi.org/10.21873/anticanres.17913
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Successful Reconstruction of Recurrent Perineal Hernia After APR Using a Vertical Rectus Abdominis Myocutaneous Flap: A Salvage Option for a Refractory Case
KEN YONEMITSU, HIROAKI KASASHIMA, TATSUNARI FUKUOKA, AKIHIRO TANAKA, SHINTARO OZAWA, TSUYOSHI NISHIYAMA, YUKI SEKI, MASATSUNE SHIBUTANI and KIYOSHI MAEDA

Anticancer Research December 2025, 45 (12) 5813-5817; DOI: https://doi.org/10.21873/anticanres.17914
Open Access
FDG- and MET-PET Imaging Reveal Glucose and Methionine Addiction in a Primary Endometrial Cancer and Methionine Addiction only in a Para-aortic Lymph-node Metastasis in a 58-year-old Patient
YOHEI ASANO, TOSHIHIKO SATO, CHIHIRO HOZUMI, QINGHONG HAN, SHUKUAN LI, BYUNG MO KANG, JIN SOO KIM, YUTA MIYASHI, NORIO YAMAMOTO, KATSUHIRO HAYASHI, HIROAKI KIMURA, SHINJI MIWA, KENTARO IGARASHI, TAKASHI HIGUCHI, SEI MORINAGA, HIROYUKI TSUCHIYA, SATORU DEMURA and ROBERT M. HOFFMAN

Anticancer Research December 2025, 45 (12) 5819-5824; DOI: https://doi.org/10.21873/anticanres.17915

Abstracts of the 15th International Charité Mayo Conference on “Global Perspectives and Future Directions in Women’s Cancer”

Open Access
ABSTRACTS OF THE 15th INTERNATIONAL CHARITÉ MAYO CONFERENCE ON “GLOBAL PERSPECTIVES AND FUTURE DIRECTIONS IN WOMEN’S CANCER”
Anticancer Research December 2025, 45 (12) 5825-5864; DOI: https://doi.org/10.21873/anticanres.17916

Corrigenda

Open Access
Corrigenda
Anticancer Research December 2025, 45 (12) 5865-5870; DOI: https://doi.org/10.21873/anticanres.17917

Index

Open Access
Index
Anticancer Research December 2025, 45 (12) 5871-6032; DOI: https://doi.org/10.21873/anticanres.17918

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Clinical Studies

Case Reports

Abstracts of the 15th International Charité Mayo Conference on “Global Perspectives and Future Directions in Women’s Cancer”

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