Anticancer Research: 45 (11)

November 2025; Volume 45,Issue 11

Reviews

Open Access
Clinical Applications of Artificial Intelligence in Uveal Melanoma
WILLIAM F. CHADWICK, SANJAY GANESH, ALBERT K. DADZIE, BEHROUZ EBRAHIMI, MOJTABA RAHIMI, TAEYOON SON, REEM ALAHMADI, XINCHENG YAO and MICHAEL J. HEIFERMAN

Anticancer Research November 2025, 45 (11) 4669-4681; DOI: https://doi.org/10.21873/anticanres.17817
Open Access
Mendelian Randomization Studies on Actinic Keratosis
IDA M. HEERFORDT, FREDERIK VIGGO LAUTRUP ESMANN and HENRIK HORWITZ

Anticancer Research November 2025, 45 (11) 4683-4687; DOI: https://doi.org/10.21873/anticanres.17818
Open Access
Management of Bladder Cancer During Pregnancy: A Narrative Review
LUCIO DELL’ATTI

Anticancer Research November 2025, 45 (11) 4689-4695; DOI: https://doi.org/10.21873/anticanres.17819

Experimental Studies

Open Access
Focused Ultrasound-mediated Disruption of Plasma Protein Binding Enhances Chemotherapeutic Effects of Paclitaxel on Xenografted Ovarian Cancer in Mice
SEUNG-SCHIK YOO, KATHRYN BANISH, ABDUELRAHMAN FAHMI, CAROLYN GLASENER, KYUNGHO YOON, SWATI BETHARIA, YONGZHI ZHANG, KEVIN ELIAS and NEIL HOROWITZ

Anticancer Research November 2025, 45 (11) 4697-4715; DOI: https://doi.org/10.21873/anticanres.17820
Open Access
Phenotypic Alteration and Suppression of Cytotoxicity of Decidual NK Cells After Co-culturing With Different Trophoblastic Cell Lines
KORNÉL F. LAKATOS, KEVIN M. ELIAS, KATHLEEN HASSELBLATT, GYÖRGY L. VÉGH, THOMAS MCELRATH, ROSS S. BERKOWITZ and VILMOS FÜLÖP

Anticancer Research November 2025, 45 (11) 4717-4727; DOI: https://doi.org/10.21873/anticanres.17821
Open Access
Fibroblast Supernatants Modulate Treatment Responses in Human Papillomavirus Positive and Negative Oropharyngeal Cancer Cell Lines
MADELEINE BIRGERSSON, TERÉZIA CHABANOVÁ, EMILIA WIECHEC, OURANIA N. KOSTOPOULOU and TINA DALIANIS

Anticancer Research November 2025, 45 (11) 4729-4742; DOI: https://doi.org/10.21873/anticanres.17822
Open Access
DDX39 Is Down-regulated in Chromophobe Renal Cell Carcinoma Tissues, Whereas Overexpression Is Associated With Shorter Patient Survival
SHIN-NOSUKE YAMASHITA, YOSHIATSU TANAKA, SHAJEDUL ISLAM, TAKAO KITAGAWA, KAZUHIRO TOKUDA, DURGA PAUDEL, SARITA GIRI, TOHRU OHTA, FUMIYA HARADA, HIROKI NAGAYASU and YASUHIRO KURAMITSU

Anticancer Research November 2025, 45 (11) 4743-4749; DOI: https://doi.org/10.21873/anticanres.17823
Open Access
Contribution of Xeroderma Pigmentosum Complementation Group C Genotypes to Colorectal Cancer in Taiwanese
YUH-FENG TSAI, MING-HSIEN WU, TZU-CHIEH LIN, TE-CHENG YUEH, HOU-YU SHIH, YUN-CHI WANG, JAI-SING YANG, YI-CHIH HUNG, TAO-WEI KE, CHIA-WEN TSAI, DA-TIAN BAU and WEN-SHIN CHANG

Anticancer Research November 2025, 45 (11) 4751-4763; DOI: https://doi.org/10.21873/anticanres.17824
Open Access
Simultaneous Targeting of Multiple Hallmarks of Cancer With Recombinant Methioninase, Rapamycin and Chloroquine Is Specific and Synergistic to MiaPaCa-2 Pancreatic-Cancer Cells in Contrast to Hs-27 Normal Fibroblasts
JINSOO KIM, QINGHONG HAN, SHUKUAN LI, BYUNG MO KANG, KOHEI MIZUTA, YOHEI ASANO, YUTA MIYASHI, MICHAEL BOUVET and ROBERT M. HOFFMAN

Anticancer Research November 2025, 45 (11) 4765-4770; DOI: https://doi.org/10.21873/anticanres.17825
Open Access
Impact of Interleukin-12B Genotypes on Breast Cancer Risk
CHIH-CHIANG HUNG, YUN-CHI WANG, CHIA-HUA LIU, MENG-LIANG LIN, SHIH-SHUN CHEN, HOU-YU SHIH, YA-CHEN YANG, TE-CHUN HSIA, CHEN-HSIEN SU, WEN-SHIN CHANG, DA-TIAN BAU and CHIA-WEN TSAI

Anticancer Research November 2025, 45 (11) 4771-4781; DOI: https://doi.org/10.21873/anticanres.17826
Open Access
OIP5-AS1 Positively Regulates the Proliferation of Colorectal Cancer Cells by Repressing Apoptosis
YOJIRO KOTAKE, YOSHINOBU TANIGAWA, HIKARI IKENAGA and TERUKI KITAGAWA

Anticancer Research November 2025, 45 (11) 4783-4790; DOI: https://doi.org/10.21873/anticanres.17827
Open Access
Triple Combination of Recombinant Methioninase and the Anti-parasitic Drugs Ivermectin, and Chloroquine Selectively Eradicates Pancreatic Cancer Cells While Sparing Normal Fibroblasts
YOHEI ASANO, QINGHONG HAN, SHUKUAN LI, KOHEI MIZUTA, BYUNG MO KANG, JIN SOO KIM, YUTA MIYASHI, NORIO YAMAMOTO, KATSUHIRO HAYASHI, HIROAKI KIMURA, SHINJI MIWA, KENTARO IGARASHI, TAKASHI HIGUCHI, SEI MORINAGA, HIROYUKI TSUCHIYA, SATORU DEMURA and ROBERT M. HOFFMAN

Anticancer Research November 2025, 45 (11) 4791-4802; DOI: https://doi.org/10.21873/anticanres.17828
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Isolation and Characterization of Putative Cancer Stem Cells from Oral Squamous Cell Carcinoma Cells
ANA LAURA VALENÇA BIZELI, IARA GONÇALVES AQUINO, FLORENCE JUANA MARIA CUADRA-ZELAYA, PATRICIA VIANNA BONINI PALMA, TUULA SALO, RICARDO DELLA COLETTA, DÉBORA CAMPANELLA BASTOS and EDGARD GRANER

Anticancer Research November 2025, 45 (11) 4803-4815; DOI: https://doi.org/10.21873/anticanres.17829
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Nodal Modulator Regulates Chemo- and Radioresistance in Lung Cancer via the Chk2 Pathway
HYE MIN KIM, JU-YOUNG KIM, CHANG GEUN LEE, JIE-YOUNG SONG, JONG KUK PARK, JIYEON AHN, CHANG-WOO LEE, SEUNG JIN HAN, SANG-GU HWANG and JEONG-HWA BAEK

Anticancer Research November 2025, 45 (11) 4817-4826; DOI: https://doi.org/10.21873/anticanres.17830
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Role of Ubiquitin-specific Protease 1 in the Pathogenesis and Treatment of Adult T-Cell Leukemia
CHIE ISHIKAWA and NAOKI MORI

Anticancer Research November 2025, 45 (11) 4827-4840; DOI: https://doi.org/10.21873/anticanres.17831
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Senolytic Elimination of Senescent Ovarian Clear Cell Carcinoma Cells Induced by CEP-1347 With the BH3 Mimetic Navitoclax
YASUFUMI ITO, KAZUKI NAKAMURA, YURIKA NAKAGAWA-SAITO, SENRI TAKENOUCHI, SHUHEI SUZUKI, KEITA TOGASHI, ASUKA SUGAI, YUTA MITOBE, MANABU SEINO, TSUYOSHI OHTA, SATORU NAGASE, CHIFUMI KITANAKA and MASASHI OKADA

Anticancer Research November 2025, 45 (11) 4841-4851; DOI: https://doi.org/10.21873/anticanres.17832
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Efficient Inhibition of FOXM1 Expression and Viability of High-grade Meningioma Cells by Domatinostat-mediated Dual Targeting of HDAC1 and HDAC2
KAZUKI NAKAMURA, YASUFUMI ITO, YURIKA NAKAGAWA-SAITO, SENRI TAKENOUCHI, SHUHEI SUZUKI, KEITA TOGASHI, ASUKA SUGAI, YUTA MITOBE, YUKIHIKO SONODA, CHIFUMI KITANAKA and MASASHI OKADA

Anticancer Research November 2025, 45 (11) 4853-4868; DOI: https://doi.org/10.21873/anticanres.17833
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Spontaneous and Radiation-induced Mammary and Thyroid Tumorigenesis in LEW and (SD×COP)F₁ Brca1^L63X/+ Rats
YUZUKI NAKAMURA, YUKIKO NISHIMURA-YANO, MAYUMI NISHIMURA, TOSHIAKI KOKUBO, KAZUHIRO DAINO, MASARU TAKABATAKE, KENTO NAGATA, TOMOJI MASHIMO, SHIZUKO KAKINUMA, KAZUMASA INOUE and TATSUHIKO IMAOKA

Anticancer Research November 2025, 45 (11) 4869-4880; DOI: https://doi.org/10.21873/anticanres.17834
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The MDM4 Inhibitor CEP-1347 Activates Wild-type p53 in Ovarian Clear Cell Carcinoma Cells and Potently Inhibits their Growth
YASUFUMI ITO, KAZUKI NAKAMURA, YURIKA NAKAGAWA-SAITO, SHUHEI SUZUKI, KEITA TOGASHI, SENRI TAKENOUCHI, ASUKA SUGAI, MANABU SEINO, TSUYOSHI OHTA, SATORU NAGASE, CHIFUMI KITANAKA and MASASHI OKADA

Anticancer Research November 2025, 45 (11) 4881-4890; DOI: https://doi.org/10.21873/anticanres.17835
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Clearance of TP53 Mutations in ctDNA Reflects Therapeutic Response in Advanced Pancreatic Cancer Patients
YOUNG KOOG CHEON, SANG HOON LEE, DONG WOOK KIM, JUNG HUN KIM, SE MIN KIM, TAE YOON LEE and YEO-MIN YUN

Anticancer Research November 2025, 45 (11) 4891-4907; DOI: https://doi.org/10.21873/anticanres.17836
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RFC4 Drives Pancreatic Cancer Progression: Prognostic Relevance and Functional Evidence
JAE WOONG KOH and SEON-JOO PARK

Anticancer Research November 2025, 45 (11) 4909-4920; DOI: https://doi.org/10.21873/anticanres.17814
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Pulsed Electromagnetic Field Promotes Doxorubicin-induced Apoptosis by Increasing Caspase-2 Activation in MDA-MB-231 Breast Cancer Cells
SUNG-HUN WOO, YONG-HEUM LEE, BYUNG CHUL JUNG and YOON SUK KIM

Anticancer Research November 2025, 45 (11) 4921-4931; DOI: https://doi.org/10.21873/anticanres.17837
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c-MYC Protein Expression Patterns in Laryngeal-Hypopharyngeal Squamous Cell Carcinomas
SOTIRIOS PAPOULIAKOS, ARISTEIDIS CHRYSOVERGIS, VASILEIOS PAPANIKOLAOU, DIMITRIOS TSOUNIS, DIMITRIOS ROUKAS, DIMITRIOS RIGOPOULOS, GEORGE PAPANASTASIOU, EVANGELOS TSIAMBAS, PAVLOS PANTOS, NIKOLAOS POULIANITIS, ANDREAS C. LAZARIS, NIKOLAOS KAVANTZAS and EFTHYMIOS KYRODIMOS

Anticancer Research November 2025, 45 (11) 4933-4939; DOI: https://doi.org/10.21873/anticanres.17838
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Combination Strategy of Arsenic Trioxide and its Metabolite For Leukemia Treatment and Modulation of Endoplasmic Reticulum-mediated Hepatotoxicity
XIAOXIA XUE, QINGCAI HUANG, XIUYUN BAI, JUE YANG, RONGJUN DENG, WANTING YE, QIQIONG LIU, YING XING, YUXING YAO, CHENG LU and YUANYAN LIU

Anticancer Research November 2025, 45 (11) 4941-4958; DOI: https://doi.org/10.21873/anticanres.17815
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MGMT Promoter Methylation in Glioblastoma Stem Cells: Stability During Differentiation and Comparison With Surgically-resected Tumors
MASAKI YOSHIOKA, SHUNSEI NOGUCHI, YASUO IWADATE, MASAYOSHI KOBAYASHI, SHINICHIRO MOTOHASHI and YOSHINORI HIGUCHI

Anticancer Research November 2025, 45 (11) 4959-4969; DOI: https://doi.org/10.21873/anticanres.17839
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Combined Treatment of Cisplatin With Caffeic Acid Phenethyl Ester Demonstrates Additive Growth Inhibition on Non-small Cell Lung Cancer Cells
CHING-YI LEE, YU-KE FU, CHIEN-CHIH YEH, LI-KUO KUO, YING-YU KUO, CHIEH HUO, SHIH-WEI LEE, YUNG-CHIA HUANG, LI-JANE SHIH, CHIA-YANG LI, SHU-PIN HUANG, CHIH-JEN LAI and CHIH-PIN CHUU

Anticancer Research November 2025, 45 (11) 4971-4986; DOI: https://doi.org/10.21873/anticanres.17840
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JI-CJ002, a Natural Herbal Formula, Enhances the Antitumor Efficacy of FOLFOX in Colorectal Cancer by Suppressing the DDR Pathway
MIN-WOO KIM, DAEUN KIM, SANG-EUN LEE, JAEHAK AHN, BYUNGHAK PARK, CHUNHOO CHEON and SEONG-GYU KO

Anticancer Research November 2025, 45 (11) 4987-5000; DOI: https://doi.org/10.21873/anticanres.17841
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Magnolol Traverses the Blood-brain Barrier and Enhances Temozolomide-induced Intrinsic Apoptosis of Glioblastoma Cells via a p53 Redox Signaling Mechanism
GONG-JHE WU, JUI-TAI CHEN, SHING-HWA LIU, EDWIN CHEN and RUEI-MING CHEN

Anticancer Research November 2025, 45 (11) 5001-5017; DOI: https://doi.org/10.21873/anticanres.17842

Clinical Studies

Open Access
Gamma Knife Radiotherapy of Brain Metastasis Resection Cavities: Outcome Analysis of a Single-center Cohort
ÀLEX GODÓ JIMÉNEZ, GERO WIEGER, STEFANIE BREHMER, A. YASSER ABOUMADIAN, FLORIAN STIELER, FRANK A. GIORDANO and ARNE MATHIAS RUDER

Anticancer Research November 2025, 45 (11) 5019-5029; DOI: https://doi.org/10.21873/anticanres.17843
Open Access
Osteosarcoma of the Diaphysis: A Report from the Cooperative Osteosarcoma Study Group (COSS)
STEFAN S. BIELACK, CLAUDIA BLATTMANN, LEO KAGER, DANIEL BAUMHOER, ARNDT BORKHARDT, TOBIAS FEUCHTINGER, GODEHARD FRIEDEL, JENDRIK HARDES, SEMI BEN HARRABI, WOLF HASSENPFLUG, THEKLA VON KALLE, MATTHIAS KEVRIC, ANTONIA KNOLL, THOMAS KÜHNE, CLAUDIA ROSSIG, BENJAMIN SORG, MATHIAS WERNER, REINHARD WINDHAGER and STEFANIE HECKER-NOLTING

Anticancer Research November 2025, 45 (11) 5031-5043; DOI: https://doi.org/10.21873/anticanres.17844
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Efficacy and Safety of Chemoimmunotherapy in Patients With Advanced Non-small Cell Lung Cancer With Pre-existing Interstitial Pneumonia and Low PD-L1 Expression
AOSA SASADA, HAYATO KAWACHI, TADAAKI YAMADA, TAE HATA, YASUHIRO GOTO, AKIHIKO AMANO, YOSHIKI NEGI, SATOSHI WATANABE, NAOKI FURUYA, TOMOHIRO OBA, TATSUKI IKOMA, AKIRA NAKAO, KEIKO TANIMURA, HIROKAZU TANIGUCHI, AKIHIRO YOSHIMURA, TOMOYA FUKUI, DAIKI MURATA, KYOICHI KAIRA, SHINSUKE SHIOTSU, ASUKA OKADA, YUSUKE CHIHARA, TAKASHI KIJIMA and KOICHI TAKAYAMA

Anticancer Research November 2025, 45 (11) 5045-5057; DOI: https://doi.org/10.21873/anticanres.17845
Open Access
Long-term Outcomes of Carbon-ion Radiotherapy for Inoperable Locally Advanced Olfactory Neuroblastoma
HIROAKI IKAWA, MAKOTO SHINOTO, MASASHI KOTO, TOYOYUKI HANAZAWA, KAZUNORI FUGO, TOSHITAKA NAGAO, HIROTOSHI TAKIYAMA, TETSURO ISOZAKI, HIROKI KUROSAKI, SHIGERU YAMADA and HITOSHI ISHIKAWA

Anticancer Research November 2025, 45 (11) 5059-5067; DOI: https://doi.org/10.21873/anticanres.17846
Open Access
Remarkable and Durable Tumor Response to Pembrolizumab in Locally Advanced dMMR/MSI-H Rectal Cancer
AYUMU HOSOKAWA, RIN YAMADA, YUKIKO OTSUKI, HOTAKA TAMURA, AKIKO ICHIHARA, TSUYOSHI FUKUSHIMA and YOSHIHIRO KOMOHARA

Anticancer Research November 2025, 45 (11) 5069-5076; DOI: https://doi.org/10.21873/anticanres.17847
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Association Between Administration Timing and Efficacy of Nivolumab in Non-small Cell Lung Cancer Treatment
YUKI IWAHASHI, AKIHIRO TAMIYA, TSUNEHIRO TANAKA, MOTOHIRO TAMIYA, AKIHIRO TSUKAGUCHI, YUJI INAGAKI, YOSHIHIKO TANIGUCHI and KYOICHI OKISHIO

Anticancer Research November 2025, 45 (11) 5077-5084; DOI: https://doi.org/10.21873/anticanres.17848
Open Access
An Investigation of Alexithymia Personality Features Versus Outcome: A Prospective 25-year Follow-up Study in Women With Breast Cancer Symptoms
MATTI ESKELINEN, RIIKA KOSKELA, TUOMAS SELANDER, KAI KAARNIRANTA, PAULA OLLONEN and MAARET ESKELINEN

Anticancer Research November 2025, 45 (11) 5085-5094; DOI: https://doi.org/10.21873/anticanres.17849
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Prognostic Impact of Additional Resection of Bile Duct Margins in Radical Resection for Perihilar Cholangiocarcinoma
KATSUNORI SAKAMOTO, YOICHIRO UCHIDA, KENTARO KADONO, HIDENOBU KOJIMA, ASAHI SATO, TOMOAKI YOH, SHOICHI KAGEYAMA, HIROFUMI HIRAO, TAKAHIRO NISHIO, SHINYA OKUMURA, DAISUKE UEDA, MASAYUKI OKUNO, HIROTO NISHINO, KEI YAMANE, SATOSHI OGISO, TAKAYUKI ANAZAWA, KAZUYUKI NAGAI, TAKASHI ITO, TAKAMICHI ISHII and ETSURO HATANO

Anticancer Research November 2025, 45 (11) 5095-5107; DOI: https://doi.org/10.21873/anticanres.17850
Open Access
Short-term and Long-term Outcomes of Prophylactic Corticosteroid in Esophageal Cancer Surgery: A Multicenter Retrospective Study
KEISUKE MISHIMA, AKIHISA MATSUDA, HIROSHI MARUYAMA, TAKESHI MATSUTANI, NOBUTOSHI HAGIWARA, MANABU WATANABE, MINAKO KOBAYASHI, NOBUHIKO TANIAI, YUKO KITAGAWA and HIROSHI YOSHIDA

Anticancer Research November 2025, 45 (11) 5109-5120; DOI: https://doi.org/10.21873/anticanres.17851
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Comparative Analysis of Dynamic Conformal Arc Therapy and Volumetric-modulated Arc Therapy in Lung Stereotactic Body Radiation Therapy: Evaluating Dosimetric Performance, Treatment Delivery Efficiency, and Plan Robustness
JIN-KYU KANG, JAE-YONG JUNG, WON IL JANG, YOUNG-JOO SHIN, JONGWOO KIM, YOUNG MIN MOON, CHUL WON CHOI, SO HYUN PARK and BO RAM LEE

Anticancer Research November 2025, 45 (11) 5121-5138; DOI: https://doi.org/10.21873/anticanres.17852
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Efficacy and Safety of Robotic Surgery for Bulky Colorectal Tumors
HIROSHI MARUTA, KEISUKE NODA, TETSURO TOMINAGA, SHINTARO HASHIMOTO, MARIKO YAMASHITA, SHOKO TEI, RIKA ONO, MAKOTO HISANAGA, KAIDO OISHI, AYANO INAO, MASAAKI MORIYAMA, FUMITAKE UCHIDA, TOSHIO SHIRAISHI, MASAKI KUNIZAKI, TAKASHI NONAKA and KEITARO MATSUMOTO

Anticancer Research November 2025, 45 (11) 5139-5146; DOI: https://doi.org/10.21873/anticanres.17853
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Preoperative Risk Analysis for Postoperative Recurrence in Locally Advanced Rectal Cancer Following Chemoradiotherapy
DAICHI KITAGUCHI, TSUYOSHI ENOMOTO, SODAI HOSHIAI, KINJI FURUYA, SHUNTARO TSUKAMOTO, TAKAHITO NAKAJIMA and TATSUYA ODA

Anticancer Research November 2025, 45 (11) 5147-5157; DOI: https://doi.org/10.21873/anticanres.17854
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Laparoscopy-assisted Partial Cecum Resection Versus Ileocecal Resection for Non-malignant Appendiceal Neoplasms
KENTARO ABE, HIROAKI NOZAWA, KAZUHITO SASAKI, KOJI MURONO, SHIGENOBU EMOTO, YUICHIRO YOKOYAMA, YUZO NAGAI, TAKAHIDE SHINAGAWA, YUICHI TACHIKAWA, SATOSHI OKADA, TETSUO USHIKU and SOICHIRO ISHIHARA

Anticancer Research November 2025, 45 (11) 5159-5166; DOI: https://doi.org/10.21873/anticanres.17855
Open Access
Automated Prediction of Pathological Complete Response to Neoadjuvant Chemotherapy in Breast Carcinoma Using Deep Learning on Pretreatment Core Needle Biopsy Samples
MIGYEONG YANG, JINYOUNG HAN, HYUNSEON WON, SEOUNG WAN CHAE, HYUN-SOO KIM and SUNG-IM DO

Anticancer Research November 2025, 45 (11) 5167-5176; DOI: https://doi.org/10.21873/anticanres.17856
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The Posterior First Approach in Robot-assisted Radical Prostatectomy for Prostate Cancer Reduces Positive Surgical Margins on the Bladder Neck Side
YASUSHI NAKAI, NOBUMICHI TANAKA, KENTA ONISHI, DAISUKE GOTO, YOSUKE MORIZAWA, SHUNTA HORI, MAKITO MIYAKE and KIYOHIDE FUJIMOTO

Anticancer Research November 2025, 45 (11) 5177-5184; DOI: https://doi.org/10.21873/anticanres.17857
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Efficacy of SGLT-2 Inhibitors in Preventing Cisplatin-induced Kidney Injury in Patients With Diabetes
YUSUKE ISHIGAMI, MASAYA TAKAHASHI, HITOMI NAKATSUKASA, HIRONOBU NISHIURA, YUYA KOHARA and YASUTAKA NAKAMURA

Anticancer Research November 2025, 45 (11) 5185-5190; DOI: https://doi.org/10.21873/anticanres.17858
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Association of Tumor Budding Grade With Immunohistochemical Expression of Thrombin and PAR-1 in Pancreatic Ductal Adenocarcinoma
ANTEJA KRIŠTIĆ, IVAN FRANIN, TONĆI VODOPIĆ, HRVOJE LONČAR, TOMISLAVA GRGURIĆ, MONICA STEPHANY KIRIGIN, ČEDNA TOMASOVIĆ-LONČARIĆ and HRVOJE ČUPIĆ

Anticancer Research November 2025, 45 (11) 5191-5202; DOI: https://doi.org/10.21873/anticanres.17859
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Prognostic Impact of Albumin Bilirubin Score In Patients Undergoing Surgery for Perihilar Cholangiocarcinoma
ATSUSHI MIKI, YASUNARU SAKUMA, TAKUMI TERATANI, HIDEKI SASANUMA, WATARU NISHIMURA and HIRONORI YAMAGUCHI

Anticancer Research November 2025, 45 (11) 5203-5211; DOI: https://doi.org/10.21873/anticanres.17860
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Body Weight Loss at Recurrence as an Independent Prognostic Factor in Patients With Recurrent Esophageal Cancer After Esophagectomy Who Receive First-line Treatment After Recurrence
TORU AOYAMA, YUKIO MAEZAWA, ITARU HASHIMOTO, SOSUKE YAMAMOTO, RYUKI ESASHI, HIDEAKI SUEMATSU, KENTARO HARA, KEISUKE KAZAMA, MAMORU UCHIYAMA, HARUHIKO CHO, AYAKO TAMAGAWA, AYA SAITO and NORIO YUKAWA

Anticancer Research November 2025, 45 (11) 5213-5223; DOI: https://doi.org/10.21873/anticanres.17861

Case Reports

Open Access
Very Rapid Eradication of a Large Squamous-Cell Carcinoma of the Head and Neck Treated With First-line Combination Chemotherapy, a Low-methionine Diet, and Oral Recombinant Methioninase
YOHEI ASANO, QINGHONG HAN, SHUKUAN LI, KOHEI MIZUTA, BYUNG MO KANG, JIN SOO KIM, YUTA MIYASHI, NORIO YAMAMOTO, KATSUHIRO HAYASHI, HIROAKI KIMURA, SHINJI MIWA, KENTARO IGARASHI, TAKASHI HIGUCHI, SEI MORINAGA, HIROYUKI TSUCHIYA, SATORU DEMURA and ROBERT M. HOFFMAN

Anticancer Research November 2025, 45 (11) 5225-5231; DOI: https://doi.org/10.21873/anticanres.17862
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Osteosclerosis and Meningioma: Implicating the Tumor Suppressor Gene AMER1/WTX
ASHWIN KUMARIA, PETER WEIR, ROBERT GOLDSPRING, IAN SCOTT and ALEX LEGGATE

Anticancer Research November 2025, 45 (11) 5233-5237; DOI: https://doi.org/10.21873/anticanres.17863
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Pathological Complete Response in Locally-advanced MSI-H/dMMR Sigmoid Colon Cancer Treated With Pembrolizumab and Abdominal Reconstruction
MASASHI SHIMASAKI, YUKI KIYOZUMI, RYOTA OHMURA, KOZUE MATSUISHI, TOMO HORINOUCHI, TOSHIHIKO YUSA, MASAYO TSUKAMOTO, TAISUKE YAGI, TAKAYOSHI KAIDA, KOTA ARIMA, KENJI SHIMIZU, KENSUKE YAMAMURA, KENSUKE SAKATA, YASUO SAKAMOTO, HISANOBU ODA, TAKIHIRO KAMIO and KATSUNORI IMAI

Anticancer Research November 2025, 45 (11) 5239-5246; DOI: https://doi.org/10.21873/anticanres.17864

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