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Research ArticleClinical Studies

Real-world Outcomes of Enfortumab Vedotin in Elderly Patients With Metastatic Urothelial Carcinoma

KYOSUKE NISHIO, KENSUKE HIROSUNA, TAIZO UCHIMOTO, HEIMA NIIGAWA, SHO KAKUMAE, TAISUKE JO, HIROFUMI MORINAKA, WATARU FUKUOKAYA, ATSUHIKO YOSHIZAWA, MASANOBU SARUTA, MAMORU HASHIMOTO, TAKAFUMI MINAMI, YUTAKA YAMAMOTO, MORITOSHI SAKAMOTO, KAZUKI NISHIMURA, RYOICHI MAENOSONO, TAKUYA TSUJINO, YUKI YOSHIKAWA, FUMIHIKO URABE, KEIICHIRO MORI, TAKAFUMI YANAGISAWA, SHUNSUKE TSUDUKI, KIYOSHI TAKAHARA, TERUO INAMOTO, KAZUTOSHI FUJITA, TAKAHIRO KIMURA, HARUHITO AZUMA and KAZUMASA KOMURA
Anticancer Research October 2025, 45 (10) 4575-4583; DOI: https://doi.org/10.21873/anticanres.17803
KYOSUKE NISHIO
1Department of Urology, Osaka Medical and Pharmaceutical University, Osaka, Japan;
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KENSUKE HIROSUNA
1Department of Urology, Osaka Medical and Pharmaceutical University, Osaka, Japan;
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TAIZO UCHIMOTO
1Department of Urology, Osaka Medical and Pharmaceutical University, Osaka, Japan;
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HEIMA NIIGAWA
2Department of Urology, Kawasaki Medical School, Okayama, Japan;
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SHO KAKUMAE
2Department of Urology, Kawasaki Medical School, Okayama, Japan;
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TAISUKE JO
2Department of Urology, Kawasaki Medical School, Okayama, Japan;
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HIROFUMI MORINAKA
2Department of Urology, Kawasaki Medical School, Okayama, Japan;
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WATARU FUKUOKAYA
3Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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ATSUHIKO YOSHIZAWA
4Department of Urology, Fujita-Health University School of Medicine, Nagoya, Japan;
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MASANOBU SARUTA
4Department of Urology, Fujita-Health University School of Medicine, Nagoya, Japan;
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MAMORU HASHIMOTO
5Department of Urology, Kindai University Faculty of Medicine, Osaka, Japan;
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TAKAFUMI MINAMI
5Department of Urology, Kindai University Faculty of Medicine, Osaka, Japan;
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YUTAKA YAMAMOTO
5Department of Urology, Kindai University Faculty of Medicine, Osaka, Japan;
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MORITOSHI SAKAMOTO
1Department of Urology, Osaka Medical and Pharmaceutical University, Osaka, Japan;
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KAZUKI NISHIMURA
1Department of Urology, Osaka Medical and Pharmaceutical University, Osaka, Japan;
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RYOICHI MAENOSONO
1Department of Urology, Osaka Medical and Pharmaceutical University, Osaka, Japan;
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TAKUYA TSUJINO
1Department of Urology, Osaka Medical and Pharmaceutical University, Osaka, Japan;
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YUKI YOSHIKAWA
1Department of Urology, Osaka Medical and Pharmaceutical University, Osaka, Japan;
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FUMIHIKO URABE
3Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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KEIICHIRO MORI
3Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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TAKAFUMI YANAGISAWA
3Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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SHUNSUKE TSUDUKI
3Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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KIYOSHI TAKAHARA
4Department of Urology, Fujita-Health University School of Medicine, Nagoya, Japan;
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TERUO INAMOTO
6Department of Urology, Hamamatsu University School of Medicine, Osaka, Japan
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KAZUTOSHI FUJITA
5Department of Urology, Kindai University Faculty of Medicine, Osaka, Japan;
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TAKAHIRO KIMURA
3Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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  • For correspondence: tkimura0809{at}gmail.com
HARUHITO AZUMA
1Department of Urology, Osaka Medical and Pharmaceutical University, Osaka, Japan;
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KAZUMASA KOMURA
2Department of Urology, Kawasaki Medical School, Okayama, Japan;
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  • For correspondence: k.komura{at}med.kawasaki-m.ac.jp
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Anticancer Research: 45 (10)
Anticancer Research
Vol. 45, Issue 10
October 2025
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Real-world Outcomes of Enfortumab Vedotin in Elderly Patients With Metastatic Urothelial Carcinoma
KYOSUKE NISHIO, KENSUKE HIROSUNA, TAIZO UCHIMOTO, HEIMA NIIGAWA, SHO KAKUMAE, TAISUKE JO, HIROFUMI MORINAKA, WATARU FUKUOKAYA, ATSUHIKO YOSHIZAWA, MASANOBU SARUTA, MAMORU HASHIMOTO, TAKAFUMI MINAMI, YUTAKA YAMAMOTO, MORITOSHI SAKAMOTO, KAZUKI NISHIMURA, RYOICHI MAENOSONO, TAKUYA TSUJINO, YUKI YOSHIKAWA, FUMIHIKO URABE, KEIICHIRO MORI, TAKAFUMI YANAGISAWA, SHUNSUKE TSUDUKI, KIYOSHI TAKAHARA, TERUO INAMOTO, KAZUTOSHI FUJITA, TAKAHIRO KIMURA, HARUHITO AZUMA, KAZUMASA KOMURA
Anticancer Research Oct 2025, 45 (10) 4575-4583; DOI: 10.21873/anticanres.17803

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Real-world Outcomes of Enfortumab Vedotin in Elderly Patients With Metastatic Urothelial Carcinoma
KYOSUKE NISHIO, KENSUKE HIROSUNA, TAIZO UCHIMOTO, HEIMA NIIGAWA, SHO KAKUMAE, TAISUKE JO, HIROFUMI MORINAKA, WATARU FUKUOKAYA, ATSUHIKO YOSHIZAWA, MASANOBU SARUTA, MAMORU HASHIMOTO, TAKAFUMI MINAMI, YUTAKA YAMAMOTO, MORITOSHI SAKAMOTO, KAZUKI NISHIMURA, RYOICHI MAENOSONO, TAKUYA TSUJINO, YUKI YOSHIKAWA, FUMIHIKO URABE, KEIICHIRO MORI, TAKAFUMI YANAGISAWA, SHUNSUKE TSUDUKI, KIYOSHI TAKAHARA, TERUO INAMOTO, KAZUTOSHI FUJITA, TAKAHIRO KIMURA, HARUHITO AZUMA, KAZUMASA KOMURA
Anticancer Research Oct 2025, 45 (10) 4575-4583; DOI: 10.21873/anticanres.17803
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Keywords

  • enfortumab vedotin
  • metastatic urothelial carcinoma
  • overall survival
  • elderly patients
  • efficacy
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