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Research ArticleClinical Studies

Elimination of High-grade Gliomas Through Induced Cytolysis, Elucidated by Two Patient Cases

CHRISTOS PANOTOPOULOS, GEORGE ATHANASIOU, STAVROS STAVROPOULOS, NICK BOUTOS, SHAILESH RAO, GEORGE PANAYOTOU, NEELAM K. VENKATARAMANA and GUNNAR RONQUIST
Anticancer Research January 2025, 45 (1) 201-207; DOI: https://doi.org/10.21873/anticanres.17405
CHRISTOS PANOTOPOULOS
1Neurosurgical Department, Mediterraneo Hospital, Glyfada, Greece;
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GEORGE ATHANASIOU
1Neurosurgical Department, Mediterraneo Hospital, Glyfada, Greece;
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STAVROS STAVROPOULOS
1Neurosurgical Department, Mediterraneo Hospital, Glyfada, Greece;
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NICK BOUTOS
1Neurosurgical Department, Mediterraneo Hospital, Glyfada, Greece;
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SHAILESH RAO
2St. John’s National Academy of Health Sciences, Bengaluru, India;
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GEORGE PANAYOTOU
3Biomedical Sciences Research Center “Alexander Fleming”, Vari, Greece;
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NEELAM K. VENKATARAMANA
4Brains Super Specialty Hospital, Bengaluru, India;
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GUNNAR RONQUIST
5Department of Medical Sciences, Clinical Chemistry, University of Uppsala, Uppsala, Sweden
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  • For correspondence: gunnar.ronquist@akademiska.se
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Anticancer Research: 45 (1)
Anticancer Research
Vol. 45, Issue 1
January 2025
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Elimination of High-grade Gliomas Through Induced Cytolysis, Elucidated by Two Patient Cases
CHRISTOS PANOTOPOULOS, GEORGE ATHANASIOU, STAVROS STAVROPOULOS, NICK BOUTOS, SHAILESH RAO, GEORGE PANAYOTOU, NEELAM K. VENKATARAMANA, GUNNAR RONQUIST
Anticancer Research Jan 2025, 45 (1) 201-207; DOI: 10.21873/anticanres.17405

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Elimination of High-grade Gliomas Through Induced Cytolysis, Elucidated by Two Patient Cases
CHRISTOS PANOTOPOULOS, GEORGE ATHANASIOU, STAVROS STAVROPOULOS, NICK BOUTOS, SHAILESH RAO, GEORGE PANAYOTOU, NEELAM K. VENKATARAMANA, GUNNAR RONQUIST
Anticancer Research Jan 2025, 45 (1) 201-207; DOI: 10.21873/anticanres.17405
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  • Article
    • Abstract
    • Amino Acid Transport into Human Glia and Glioma Cells
    • Induced Cytolysis of Human Glioma Cells In Vitro
    • Introductory Patient Studies
    • Therapeutic Limitations
    • The Crucial Role of EVs for Glioma Cell Proliferation and Progression
    • Case 1 [first reported by Ganapathy et al., 2023 (20)]
    • Case 2
    • Conclusion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • PDF

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Keywords

  • glioblastoma
  • DAB
  • targeted therapy
  • amino acids
  • cytolysis
  • review
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