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Research ArticleClinical Studies

Pathological Complete Response to Liver Metastasis With Pembrolizumab in a Previously Treated Patient With Microsatellite Instability-high Colorectal Cancer

AYUMU HOSOKAWA, HOTAKA TAMURA, AKIKO ICHIHARA, NAOYA IMAMURA, KENGO KAI, TSUYOSHI FUKUSHIMA, ATSUSHI NANASHIMA and YOSHIHIRO KOMOHARA
Anticancer Research September 2024, 44 (9) 4119-4125; DOI: https://doi.org/10.21873/anticanres.17241
AYUMU HOSOKAWA
1Department of Clinical Oncology, University of Miyazaki Hospital, Miyazaki, Japan;
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  • For correspondence: ayhosoka{at}med.miyazaki-u.ac.jp
HOTAKA TAMURA
2Division of Gastroenterology and Hepatology, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan;
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AKIKO ICHIHARA
3Department of Surgery, University of Miyazaki Faculty of Medicine, Miyazaki, Japan;
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NAOYA IMAMURA
3Department of Surgery, University of Miyazaki Faculty of Medicine, Miyazaki, Japan;
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KENGO KAI
3Department of Surgery, University of Miyazaki Faculty of Medicine, Miyazaki, Japan;
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TSUYOSHI FUKUSHIMA
4Section of Oncopathology and Regenerative Biology, Department of Pathology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan;
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ATSUSHI NANASHIMA
3Department of Surgery, University of Miyazaki Faculty of Medicine, Miyazaki, Japan;
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YOSHIHIRO KOMOHARA
5Department of Cell Pathology, Graduate School of Medicine, Kumamoto University, Kumamoto, Japan
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  • For correspondence: ycomo{at}kumamoto-u.ac.jp
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Article Information

vol. 44 no. 9 4119-4125
DOI 
https://doi.org/10.21873/anticanres.17241
PMID 
39197935

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received June 18, 2024
  • Revision received July 9, 2024
  • Accepted July 10, 2024
  • Published online August 28, 2024.

Copyright & Usage 
Copyright © 2024 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. AYUMU HOSOKAWA1⇑,
  2. HOTAKA TAMURA2,
  3. AKIKO ICHIHARA3,
  4. NAOYA IMAMURA3,
  5. KENGO KAI3,
  6. TSUYOSHI FUKUSHIMA4,
  7. ATSUSHI NANASHIMA3 and
  8. YOSHIHIRO KOMOHARA5⇑
  1. 1Department of Clinical Oncology, University of Miyazaki Hospital, Miyazaki, Japan;
  2. 2Division of Gastroenterology and Hepatology, Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan;
  3. 3Department of Surgery, University of Miyazaki Faculty of Medicine, Miyazaki, Japan;
  4. 4Section of Oncopathology and Regenerative Biology, Department of Pathology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan;
  5. 5Department of Cell Pathology, Graduate School of Medicine, Kumamoto University, Kumamoto, Japan
  1. Correspondence to: Yoshihiro Komohara, Department of Cell Pathology, Graduate School of Medicine, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan. Tel: +81 963735095, Fax: +81 963735096, e-mail: ycomo{at}kumamoto-u.ac.jp;
  2. Correspondence to: Ayumu Hosokawa, Department of Clinical Oncology, University of Miyazaki Hospital, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan. Tel: +81 985859758, Fax: +81 985859709, e-mail: ayhosoka{at}med.miyazaki-u.ac.jp
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Pathological Complete Response to Liver Metastasis With Pembrolizumab in a Previously Treated Patient With Microsatellite Instability-high Colorectal Cancer
AYUMU HOSOKAWA, HOTAKA TAMURA, AKIKO ICHIHARA, NAOYA IMAMURA, KENGO KAI, TSUYOSHI FUKUSHIMA, ATSUSHI NANASHIMA, YOSHIHIRO KOMOHARA
Anticancer Research Sep 2024, 44 (9) 4119-4125; DOI: 10.21873/anticanres.17241

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Pathological Complete Response to Liver Metastasis With Pembrolizumab in a Previously Treated Patient With Microsatellite Instability-high Colorectal Cancer
AYUMU HOSOKAWA, HOTAKA TAMURA, AKIKO ICHIHARA, NAOYA IMAMURA, KENGO KAI, TSUYOSHI FUKUSHIMA, ATSUSHI NANASHIMA, YOSHIHIRO KOMOHARA
Anticancer Research Sep 2024, 44 (9) 4119-4125; DOI: 10.21873/anticanres.17241
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Keywords

  • colorectal cancer
  • liver metastasis
  • microsatellite instability-high
  • pembrolizumab
  • PD-L1
  • CD169
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