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Research ArticleExperimental Studies

Tranilast Inhibits TRPV2 and Suppresses Fibrosis Progression and Weight Gain in a NASH Model Mouse

TAKAHIRO NAGATA, SATOSHI SHAKADO, ERI YAMAUCHI, HIROAKI TOKUSHIGE, TAKASHI MIYAYAMA, RYO YAMAUCHI, HIROMI FUKUDA, ATSUSHI FUKUNAGA, TAKASHI TANAKA, KAZUHIDE TAKATA, KEIJI YOKOYAMA and FUMIHITO HIRAI
Anticancer Research August 2024, 44 (8) 3593-3604; DOI: https://doi.org/10.21873/anticanres.17182
TAKAHIRO NAGATA
Departments of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
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  • For correspondence: takahiro1328{at}hotmail.co.jp
SATOSHI SHAKADO
Departments of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
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ERI YAMAUCHI
Departments of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
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HIROAKI TOKUSHIGE
Departments of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
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TAKASHI MIYAYAMA
Departments of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
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RYO YAMAUCHI
Departments of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
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HIROMI FUKUDA
Departments of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
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ATSUSHI FUKUNAGA
Departments of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
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TAKASHI TANAKA
Departments of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
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KAZUHIDE TAKATA
Departments of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
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KEIJI YOKOYAMA
Departments of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
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FUMIHITO HIRAI
Departments of Gastroenterology and Medicine, Faculty of Medicine, Fukuoka University, Fukuoka, Japan
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Anticancer Research: 44 (8)
Anticancer Research
Vol. 44, Issue 8
August 2024
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Tranilast Inhibits TRPV2 and Suppresses Fibrosis Progression and Weight Gain in a NASH Model Mouse
TAKAHIRO NAGATA, SATOSHI SHAKADO, ERI YAMAUCHI, HIROAKI TOKUSHIGE, TAKASHI MIYAYAMA, RYO YAMAUCHI, HIROMI FUKUDA, ATSUSHI FUKUNAGA, TAKASHI TANAKA, KAZUHIDE TAKATA, KEIJI YOKOYAMA, FUMIHITO HIRAI
Anticancer Research Aug 2024, 44 (8) 3593-3604; DOI: 10.21873/anticanres.17182

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Tranilast Inhibits TRPV2 and Suppresses Fibrosis Progression and Weight Gain in a NASH Model Mouse
TAKAHIRO NAGATA, SATOSHI SHAKADO, ERI YAMAUCHI, HIROAKI TOKUSHIGE, TAKASHI MIYAYAMA, RYO YAMAUCHI, HIROMI FUKUDA, ATSUSHI FUKUNAGA, TAKASHI TANAKA, KAZUHIDE TAKATA, KEIJI YOKOYAMA, FUMIHITO HIRAI
Anticancer Research Aug 2024, 44 (8) 3593-3604; DOI: 10.21873/anticanres.17182
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Keywords

  • Gubra-Amylin nonalcoholic steatohepatitis
  • nonalcoholic fatty liver disease
  • obesity control
  • tranilast
  • transient receptor potential vanilloid 2
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