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Research ArticleExperimental Studies

Adipose-derived Mesenchymal Stem Cell Transplantation Improves Ovarian Function and Oocyte Quality in Aged Mice

TOYOFUMI HIRAKAWA, FUSANORI YOTSUMOTO, SHIORI IMI, NORIKO ITO, KEISUKE ISHIWATA, KAZUHIKO NAKABAYASHI, ASAKO WATANABE, NAOTO SHIRASU, DAICHI URUSHIYAMA, KOHEI MIYATA, SHINYA TAKAHASHI, TSUKASA BABA, KENICHIRO HATA, SHIN’ICHIRO YASUNAGA and SHINGO MIYAMOTO
Anticancer Research August 2024, 44 (8) 3577-3586; DOI: https://doi.org/10.21873/anticanres.17180
TOYOFUMI HIRAKAWA
1Department of Obstetrics & Gynecology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
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  • For correspondence: thira{at}fukuoka-u.ac.jp
FUSANORI YOTSUMOTO
1Department of Obstetrics & Gynecology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
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SHIORI IMI
1Department of Obstetrics & Gynecology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
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NORIKO ITO
2Department of Maternal-Fetal Biology, National Center for Child Health and Development, Tokyo, Japan;
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KEISUKE ISHIWATA
2Department of Maternal-Fetal Biology, National Center for Child Health and Development, Tokyo, Japan;
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KAZUHIKO NAKABAYASHI
2Department of Maternal-Fetal Biology, National Center for Child Health and Development, Tokyo, Japan;
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ASAKO WATANABE
3Department of Electronics Engineering and Computer Science, Faculty of Engineering, Fukuoka University, Fukuoka, Japan;
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NAOTO SHIRASU
4Department of Biochemistry, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
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DAICHI URUSHIYAMA
1Department of Obstetrics & Gynecology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
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KOHEI MIYATA
1Department of Obstetrics & Gynecology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
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SHINYA TAKAHASHI
3Department of Electronics Engineering and Computer Science, Faculty of Engineering, Fukuoka University, Fukuoka, Japan;
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TSUKASA BABA
5Department of Obstetrics & Gynecology, School of Medicine, Iwate Medical University, Iwate, Japan
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KENICHIRO HATA
2Department of Maternal-Fetal Biology, National Center for Child Health and Development, Tokyo, Japan;
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SHIN’ICHIRO YASUNAGA
4Department of Biochemistry, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
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SHINGO MIYAMOTO
5Department of Obstetrics & Gynecology, School of Medicine, Iwate Medical University, Iwate, Japan
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  • For correspondence: smiya3500{at}gmail.com
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Article Information

vol. 44 no. 8 3577-3586
DOI 
https://doi.org/10.21873/anticanres.17180
PubMed 
39060058

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received May 21, 2024
  • Revision received June 11, 2024
  • Accepted June 12, 2024
  • Published online July 26, 2024.

Copyright & Usage 
Copyright © 2024 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. TOYOFUMI HIRAKAWA1⇑,
  2. FUSANORI YOTSUMOTO1,
  3. SHIORI IMI1,
  4. NORIKO ITO2,
  5. KEISUKE ISHIWATA2,
  6. KAZUHIKO NAKABAYASHI2,
  7. ASAKO WATANABE3,
  8. NAOTO SHIRASU4,
  9. DAICHI URUSHIYAMA1,
  10. KOHEI MIYATA1,
  11. SHINYA TAKAHASHI3,
  12. TSUKASA BABA5,
  13. KENICHIRO HATA2,
  14. SHIN’ICHIRO YASUNAGA4 and
  15. SHINGO MIYAMOTO5⇑
  1. 1Department of Obstetrics & Gynecology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
  2. 2Department of Maternal-Fetal Biology, National Center for Child Health and Development, Tokyo, Japan;
  3. 3Department of Electronics Engineering and Computer Science, Faculty of Engineering, Fukuoka University, Fukuoka, Japan;
  4. 4Department of Biochemistry, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
  5. 5Department of Obstetrics & Gynecology, School of Medicine, Iwate Medical University, Iwate, Japan
  1. Correspondence to: Toyofumi Hirakawa, Department of Obstetrics & Gynecology, Faculty of Medicine, Fukuoka University, 7-45-1 Nanakuma, Jonan-ku, Fukuoka 814-0180, Japan. Tel: +81 928011011, Fax: +81 928654114, e-mail: thira{at}fukuoka-u.ac.jp;
  2. Correspondence to: Shingo Miyamoto, Department of Obstetrics & Gynecology, School of Medicine, Iwate Medical University, 2-128-14 Sugukita, Kasugashi, Fukuoka 816-0864, Japan. Tel: +81 929852046, Fax: +81 929852046, e-mail: smiya3500{at}gmail.com
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Adipose-derived Mesenchymal Stem Cell Transplantation Improves Ovarian Function and Oocyte Quality in Aged Mice
TOYOFUMI HIRAKAWA, FUSANORI YOTSUMOTO, SHIORI IMI, NORIKO ITO, KEISUKE ISHIWATA, KAZUHIKO NAKABAYASHI, ASAKO WATANABE, NAOTO SHIRASU, DAICHI URUSHIYAMA, KOHEI MIYATA, SHINYA TAKAHASHI, TSUKASA BABA, KENICHIRO HATA, SHIN’ICHIRO YASUNAGA, SHINGO MIYAMOTO
Anticancer Research Aug 2024, 44 (8) 3577-3586; DOI: 10.21873/anticanres.17180

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Adipose-derived Mesenchymal Stem Cell Transplantation Improves Ovarian Function and Oocyte Quality in Aged Mice
TOYOFUMI HIRAKAWA, FUSANORI YOTSUMOTO, SHIORI IMI, NORIKO ITO, KEISUKE ISHIWATA, KAZUHIKO NAKABAYASHI, ASAKO WATANABE, NAOTO SHIRASU, DAICHI URUSHIYAMA, KOHEI MIYATA, SHINYA TAKAHASHI, TSUKASA BABA, KENICHIRO HATA, SHIN’ICHIRO YASUNAGA, SHINGO MIYAMOTO
Anticancer Research Aug 2024, 44 (8) 3577-3586; DOI: 10.21873/anticanres.17180
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Keywords

  • Adipose-derived mesenchymal stem cell
  • stem cell therapy
  • ovarian function
  • oocyte quality
  • female infertility
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