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Review ArticleReview

Alterations of the Glymphatic System in Glioblastomas: A Systematic Review

GIANLUCA SCALIA, GIANLUCA FERINI, MANIKON PULLAY SILVEN, MANFREDI NOTO, ROBERTA COSTANZO, ROSARIO MAUGERI, DOMENICO GERARDO IACOPINO, VALENTINA ZAGARDO, ANNA VIOLA, GIOVANNI FEDERICO NICOLETTI and GIUSEPPE EMMANUELE UMANA
Anticancer Research August 2024, 44 (8) 3223-3230; DOI: https://doi.org/10.21873/anticanres.17140
GIANLUCA SCALIA
1Neurosurgery Clinic, Department of Head and Neck Surgery, Garibaldi Hospital, Catania, Italy;
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GIANLUCA FERINI
2Department of Radiation Oncology, REM Radioterapia srl, Viagrande, Italy;
3School of Medicine, University Kore of Enna, Enna, Italy;
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  • For correspondence: gianluca.ferini{at}unikore.it
MANIKON PULLAY SILVEN
4Neurosurgical Clinic, AOUP Paolo Giaccone, Post Graduate Residency Program in Neurologic Surgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, Palermo, Italy;
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MANFREDI NOTO
4Neurosurgical Clinic, AOUP Paolo Giaccone, Post Graduate Residency Program in Neurologic Surgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, Palermo, Italy;
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ROBERTA COSTANZO
4Neurosurgical Clinic, AOUP Paolo Giaccone, Post Graduate Residency Program in Neurologic Surgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, Palermo, Italy;
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ROSARIO MAUGERI
4Neurosurgical Clinic, AOUP Paolo Giaccone, Post Graduate Residency Program in Neurologic Surgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, Palermo, Italy;
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DOMENICO GERARDO IACOPINO
4Neurosurgical Clinic, AOUP Paolo Giaccone, Post Graduate Residency Program in Neurologic Surgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, Palermo, Italy;
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VALENTINA ZAGARDO
2Department of Radiation Oncology, REM Radioterapia srl, Viagrande, Italy;
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ANNA VIOLA
2Department of Radiation Oncology, REM Radioterapia srl, Viagrande, Italy;
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GIOVANNI FEDERICO NICOLETTI
1Neurosurgery Clinic, Department of Head and Neck Surgery, Garibaldi Hospital, Catania, Italy;
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GIUSEPPE EMMANUELE UMANA
3School of Medicine, University Kore of Enna, Enna, Italy;
5Department of Neurosurgery, Cannizzaro Hospital, Trauma and Gamma Knife Center, Catania, Italy
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Article Information

vol. 44 no. 8 3223-3230
DOI 
https://doi.org/10.21873/anticanres.17140
PMID 
39060078

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received May 17, 2024
  • Revision received June 20, 2024
  • Accepted June 24, 2024
  • Published online July 26, 2024.

Copyright & Usage 
Copyright © 2024 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. GIANLUCA SCALIA1,
  2. GIANLUCA FERINI2,3⇑,
  3. MANIKON PULLAY SILVEN4,
  4. MANFREDI NOTO4,
  5. ROBERTA COSTANZO4,
  6. ROSARIO MAUGERI4,
  7. DOMENICO GERARDO IACOPINO4,
  8. VALENTINA ZAGARDO2,
  9. ANNA VIOLA2,
  10. GIOVANNI FEDERICO NICOLETTI1 and
  11. GIUSEPPE EMMANUELE UMANA3,5
  1. 1Neurosurgery Clinic, Department of Head and Neck Surgery, Garibaldi Hospital, Catania, Italy;
  2. 2Department of Radiation Oncology, REM Radioterapia srl, Viagrande, Italy;
  3. 3School of Medicine, University Kore of Enna, Enna, Italy;
  4. 4Neurosurgical Clinic, AOUP Paolo Giaccone, Post Graduate Residency Program in Neurologic Surgery, Department of Biomedicine Neurosciences and Advanced Diagnostics, School of Medicine, University of Palermo, Palermo, Italy;
  5. 5Department of Neurosurgery, Cannizzaro Hospital, Trauma and Gamma Knife Center, Catania, Italy
  1. Correspondence to: Gianluca Ferini, REM Radioterapia srl, Via Penninazzo 11, 95029, Viagrande (CT), Italy. Tel: +39 957899569, e-mail: gianluca.ferini{at}unikore.it
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Alterations of the Glymphatic System in Glioblastomas: A Systematic Review
GIANLUCA SCALIA, GIANLUCA FERINI, MANIKON PULLAY SILVEN, MANFREDI NOTO, ROBERTA COSTANZO, ROSARIO MAUGERI, DOMENICO GERARDO IACOPINO, VALENTINA ZAGARDO, ANNA VIOLA, GIOVANNI FEDERICO NICOLETTI, GIUSEPPE EMMANUELE UMANA
Anticancer Research Aug 2024, 44 (8) 3223-3230; DOI: 10.21873/anticanres.17140

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Alterations of the Glymphatic System in Glioblastomas: A Systematic Review
GIANLUCA SCALIA, GIANLUCA FERINI, MANIKON PULLAY SILVEN, MANFREDI NOTO, ROBERTA COSTANZO, ROSARIO MAUGERI, DOMENICO GERARDO IACOPINO, VALENTINA ZAGARDO, ANNA VIOLA, GIOVANNI FEDERICO NICOLETTI, GIUSEPPE EMMANUELE UMANA
Anticancer Research Aug 2024, 44 (8) 3223-3230; DOI: 10.21873/anticanres.17140
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Keywords

  • Glioblastoma
  • glymphatic system
  • cerebrospinal fluid
  • brain neoplasms
  • lymphatic drainage
  • systematic review
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