STAT3 Contributes a Favorable Response to Pembrolizumab Through IFN-γ-induced Apoptosis in Urothelial Cancer

HIROTAKA FUCHIZAWA; KIYOHIRO ANDO; NORIKO MOTOI; TOSHIHIKO IIZUKA; MASAHARU INOUE; KOUKI MITANI; YUTA SANO; HISANORI TAKENOBU; MASAYUKI HARUTA; RITSUKO ONUKI; YOH MATSUOKA; TAKEHIKO KAMIJO; YUKIO KAGEYAMA

doi:10.21873/anticanres.16994

Research ArticleExperimental Studies

STAT3 Contributes a Favorable Response to Pembrolizumab Through IFN-γ-induced Apoptosis in Urothelial Cancer

HIROTAKA FUCHIZAWA, KIYOHIRO ANDO, NORIKO MOTOI, TOSHIHIKO IIZUKA, MASAHARU INOUE, KOUKI MITANI, YUTA SANO, HISANORI TAKENOBU, MASAYUKI HARUTA, RITSUKO ONUKI, YOH MATSUOKA, TAKEHIKO KAMIJO and YUKIO KAGEYAMA

Anticancer Research May 2024, 44 (5) 1925-1930; DOI: https://doi.org/10.21873/anticanres.16994

HIROTAKA FUCHIZAWA

1Department of Urology, Saitama Cancer Center, Saitama, Japan;

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KIYOHIRO ANDO

2Research Institute for Clinical Oncology, Saitama Cancer Center, Saitama, Japan;

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For correspondence: kiyohiro_ando@saitama-pho.jp

NORIKO MOTOI

3Department of Pathology, Saitama Cancer Center, Saitama, Japan

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TOSHIHIKO IIZUKA

3Department of Pathology, Saitama Cancer Center, Saitama, Japan

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MASAHARU INOUE

1Department of Urology, Saitama Cancer Center, Saitama, Japan;

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KOUKI MITANI

1Department of Urology, Saitama Cancer Center, Saitama, Japan;

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YUTA SANO

1Department of Urology, Saitama Cancer Center, Saitama, Japan;

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HISANORI TAKENOBU

2Research Institute for Clinical Oncology, Saitama Cancer Center, Saitama, Japan;

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MASAYUKI HARUTA

2Research Institute for Clinical Oncology, Saitama Cancer Center, Saitama, Japan;

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RITSUKO ONUKI

2Research Institute for Clinical Oncology, Saitama Cancer Center, Saitama, Japan;

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YOH MATSUOKA

1Department of Urology, Saitama Cancer Center, Saitama, Japan;

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TAKEHIKO KAMIJO

2Research Institute for Clinical Oncology, Saitama Cancer Center, Saitama, Japan;

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YUKIO KAGEYAMA

1Department of Urology, Saitama Cancer Center, Saitama, Japan;

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STAT3 Contributes a Favorable Response to Pembrolizumab Through IFN-γ-induced Apoptosis in Urothelial Cancer

Anticancer Research May 2024, 44 (5) 1925-1930; DOI: 10.21873/anticanres.16994

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STAT3 Contributes a Favorable Response to Pembrolizumab Through IFN-γ-induced Apoptosis in Urothelial Cancer

Anticancer Research May 2024, 44 (5) 1925-1930; DOI: 10.21873/anticanres.16994

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Keywords

Pembrolizumab
Urothelial carcinoma
STAT3
IFN-γ

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