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Research ArticleExperimental Studies

STAT3 Contributes a Favorable Response to Pembrolizumab Through IFN-γ-induced Apoptosis in Urothelial Cancer

HIROTAKA FUCHIZAWA, KIYOHIRO ANDO, NORIKO MOTOI, TOSHIHIKO IIZUKA, MASAHARU INOUE, KOUKI MITANI, YUTA SANO, HISANORI TAKENOBU, MASAYUKI HARUTA, RITSUKO ONUKI, YOH MATSUOKA, TAKEHIKO KAMIJO and YUKIO KAGEYAMA
Anticancer Research May 2024, 44 (5) 1925-1930; DOI: https://doi.org/10.21873/anticanres.16994
HIROTAKA FUCHIZAWA
1Department of Urology, Saitama Cancer Center, Saitama, Japan;
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KIYOHIRO ANDO
2Research Institute for Clinical Oncology, Saitama Cancer Center, Saitama, Japan;
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  • For correspondence: kiyohiro_ando@saitama-pho.jp
NORIKO MOTOI
3Department of Pathology, Saitama Cancer Center, Saitama, Japan
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TOSHIHIKO IIZUKA
3Department of Pathology, Saitama Cancer Center, Saitama, Japan
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MASAHARU INOUE
1Department of Urology, Saitama Cancer Center, Saitama, Japan;
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KOUKI MITANI
1Department of Urology, Saitama Cancer Center, Saitama, Japan;
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YUTA SANO
1Department of Urology, Saitama Cancer Center, Saitama, Japan;
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HISANORI TAKENOBU
2Research Institute for Clinical Oncology, Saitama Cancer Center, Saitama, Japan;
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MASAYUKI HARUTA
2Research Institute for Clinical Oncology, Saitama Cancer Center, Saitama, Japan;
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RITSUKO ONUKI
2Research Institute for Clinical Oncology, Saitama Cancer Center, Saitama, Japan;
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YOH MATSUOKA
1Department of Urology, Saitama Cancer Center, Saitama, Japan;
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TAKEHIKO KAMIJO
2Research Institute for Clinical Oncology, Saitama Cancer Center, Saitama, Japan;
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YUKIO KAGEYAMA
1Department of Urology, Saitama Cancer Center, Saitama, Japan;
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Article Information

vol. 44 no. 5 1925-1930
DOI 
https://doi.org/10.21873/anticanres.16994
PubMed 
38677727

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received March 15, 2024
  • Revision received March 28, 2024
  • Accepted March 29, 2024
  • Published online April 27, 2024.

Copyright & Usage 
Copyright © 2024 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. HIROTAKA FUCHIZAWA1,*,
  2. KIYOHIRO ANDO2,*⇑,
  3. NORIKO MOTOI3,
  4. TOSHIHIKO IIZUKA3,
  5. MASAHARU INOUE1,
  6. KOUKI MITANI1,
  7. YUTA SANO1,
  8. HISANORI TAKENOBU2,
  9. MASAYUKI HARUTA2,
  10. RITSUKO ONUKI2,
  11. YOH MATSUOKA1,
  12. TAKEHIKO KAMIJO2 and
  13. YUKIO KAGEYAMA1
  1. 1Department of Urology, Saitama Cancer Center, Saitama, Japan;
  2. 2Research Institute for Clinical Oncology, Saitama Cancer Center, Saitama, Japan;
  3. 3Department of Pathology, Saitama Cancer Center, Saitama, Japan
  1. Correspondence to: Kiyohiro Ando, MD, Ph.D., Research Institute for Clinical Oncology, Saitama Cancer Center, 818 Komuro, Inamachi, Kitaadachi-gun, Saitama 362-0806, Japan. E-mail: kiyohiro_ando{at}saitama-pho.jp
  1. ↵* These Authors contributed equally to this study.

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STAT3 Contributes a Favorable Response to Pembrolizumab Through IFN-γ-induced Apoptosis in Urothelial Cancer
HIROTAKA FUCHIZAWA, KIYOHIRO ANDO, NORIKO MOTOI, TOSHIHIKO IIZUKA, MASAHARU INOUE, KOUKI MITANI, YUTA SANO, HISANORI TAKENOBU, MASAYUKI HARUTA, RITSUKO ONUKI, YOH MATSUOKA, TAKEHIKO KAMIJO, YUKIO KAGEYAMA
Anticancer Research May 2024, 44 (5) 1925-1930; DOI: 10.21873/anticanres.16994

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STAT3 Contributes a Favorable Response to Pembrolizumab Through IFN-γ-induced Apoptosis in Urothelial Cancer
HIROTAKA FUCHIZAWA, KIYOHIRO ANDO, NORIKO MOTOI, TOSHIHIKO IIZUKA, MASAHARU INOUE, KOUKI MITANI, YUTA SANO, HISANORI TAKENOBU, MASAYUKI HARUTA, RITSUKO ONUKI, YOH MATSUOKA, TAKEHIKO KAMIJO, YUKIO KAGEYAMA
Anticancer Research May 2024, 44 (5) 1925-1930; DOI: 10.21873/anticanres.16994
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Keywords

  • Pembrolizumab
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  • STAT3
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