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Research ArticleExperimental Studies

Naringenin Induces Cellular Apoptosis in Melanoma Cells via Intracellular ROS Generation

PINCHA DEVAGE SAMEERA MADUSHAN FERNANDO, AO XUAN ZHEN, MEI JING PIAO, HERATH MUDIYANSELAGE UDARI LAKMINI HERATH, KYOUNG AH KANG, SANG-PIL YOON, HYE-JIN BOO, CHANG LIM HYUN and JIN WON HYUN
Anticancer Research March 2024, 44 (3) 1079-1086; DOI: https://doi.org/10.21873/anticanres.16903
PINCHA DEVAGE SAMEERA MADUSHAN FERNANDO
1Department of Biochemistry, College of Medicine, Jeju National University, Jeju, Republic of Korea;
2Jeju Research Center for Natural Medicine, Jeju National University, Jeju, Republic of Korea;
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AO XUAN ZHEN
1Department of Biochemistry, College of Medicine, Jeju National University, Jeju, Republic of Korea;
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MEI JING PIAO
1Department of Biochemistry, College of Medicine, Jeju National University, Jeju, Republic of Korea;
2Jeju Research Center for Natural Medicine, Jeju National University, Jeju, Republic of Korea;
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HERATH MUDIYANSELAGE UDARI LAKMINI HERATH
1Department of Biochemistry, College of Medicine, Jeju National University, Jeju, Republic of Korea;
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KYOUNG AH KANG
1Department of Biochemistry, College of Medicine, Jeju National University, Jeju, Republic of Korea;
2Jeju Research Center for Natural Medicine, Jeju National University, Jeju, Republic of Korea;
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SANG-PIL YOON
2Jeju Research Center for Natural Medicine, Jeju National University, Jeju, Republic of Korea;
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HYE-JIN BOO
2Jeju Research Center for Natural Medicine, Jeju National University, Jeju, Republic of Korea;
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CHANG LIM HYUN
2Jeju Research Center for Natural Medicine, Jeju National University, Jeju, Republic of Korea;
3Department of Pathology, Jeju National University Hospital, College of Medicine, Jeju National University, Jeju, Republic of Korea
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  • For correspondence: venisua{at}jejunu.ac.kr
JIN WON HYUN
1Department of Biochemistry, College of Medicine, Jeju National University, Jeju, Republic of Korea;
2Jeju Research Center for Natural Medicine, Jeju National University, Jeju, Republic of Korea;
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  • For correspondence: jinwonh{at}jejunu.ac.kr
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Article Information

vol. 44 no. 3 1079-1086
DOI 
https://doi.org/10.21873/anticanres.16903
PMID 
38423648

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received December 20, 2023
  • Revision received January 17, 2024
  • Accepted January 25, 2024
  • Published online February 29, 2024.

Copyright & Usage 
Copyright © 2024 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. PINCHA DEVAGE SAMEERA MADUSHAN FERNANDO1,2,†,
  2. AO XUAN ZHEN1,†,
  3. MEI JING PIAO1,2,
  4. HERATH MUDIYANSELAGE UDARI LAKMINI HERATH1,
  5. KYOUNG AH KANG1,2,
  6. SANG-PIL YOON2,
  7. HYE-JIN BOO2,
  8. CHANG LIM HYUN2,3⇑* and
  9. JIN WON HYUN1,2⇑*
  1. 1Department of Biochemistry, College of Medicine, Jeju National University, Jeju, Republic of Korea;
  2. 2Jeju Research Center for Natural Medicine, Jeju National University, Jeju, Republic of Korea;
  3. 3Department of Pathology, Jeju National University Hospital, College of Medicine, Jeju National University, Jeju, Republic of Korea
  1. Correspondence to: Chang Lim Hyun, Department of Pathology, Jeju National University Hospital, College of Medicine, Jeju National University, Jeju 63241, Republic of Korea. Tel: +82 647548118, e-mail: venisua{at}jejunu.ac.kr;
  2. Correspondence to: Jin Won Hyun, Department of Biochemistry, College of Medicine, Jeju National University, Jeju 63243, Republic of Korea. Tel: +82 647543838, e-mail: jinwonh{at}jejunu.ac.kr
  1. ↵† These Authors contributed equally to this work.

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Naringenin Induces Cellular Apoptosis in Melanoma Cells via Intracellular ROS Generation
PINCHA DEVAGE SAMEERA MADUSHAN FERNANDO, AO XUAN ZHEN, MEI JING PIAO, HERATH MUDIYANSELAGE UDARI LAKMINI HERATH, KYOUNG AH KANG, SANG-PIL YOON, HYE-JIN BOO, CHANG LIM HYUN, JIN WON HYUN
Anticancer Research Mar 2024, 44 (3) 1079-1086; DOI: 10.21873/anticanres.16903

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Naringenin Induces Cellular Apoptosis in Melanoma Cells via Intracellular ROS Generation
PINCHA DEVAGE SAMEERA MADUSHAN FERNANDO, AO XUAN ZHEN, MEI JING PIAO, HERATH MUDIYANSELAGE UDARI LAKMINI HERATH, KYOUNG AH KANG, SANG-PIL YOON, HYE-JIN BOO, CHANG LIM HYUN, JIN WON HYUN
Anticancer Research Mar 2024, 44 (3) 1079-1086; DOI: 10.21873/anticanres.16903
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Keywords

  • Melanoma
  • naringenin
  • oxidative stress
  • apoptosis
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