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Research ArticleExperimental Studies

Azacitidine–Hesperetin Combination Induces S-phase Cell Cycle Arrest and Apoptosis in Human Leukemia Cells

KUAN-MING LAI, RUO-HAN TSENG, YU-HUNG SHIH and YING-CHIH HUANG
Anticancer Research March 2024, 44 (3) 1033-1044; DOI: https://doi.org/10.21873/anticanres.16898
KUAN-MING LAI
1Program in Translational Medicine, National Chung Hsing University, Taichung, Taiwan, R.O.C.;
2Hemato-Oncology Division Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan, R.O.C.;
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RUO-HAN TSENG
2Hemato-Oncology Division Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan, R.O.C.;
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YU-HUNG SHIH
2Hemato-Oncology Division Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan, R.O.C.;
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YING-CHIH HUANG
3Hematology & Oncology Research Laboratory, Changhua Christian Hospital, Changhua, Taiwan, R.O.C.
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  • For correspondence: 181550{at}cch.org.tw
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Article Information

vol. 44 no. 3 1033-1044
DOI 
https://doi.org/10.21873/anticanres.16898
PMID 
38423637

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received October 19, 2023
  • Revision received December 12, 2023
  • Accepted December 22, 2023
  • Published online February 29, 2024.

Copyright & Usage 
Copyright © 2024 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. KUAN-MING LAI1,2,
  2. RUO-HAN TSENG2,
  3. YU-HUNG SHIH2 and
  4. YING-CHIH HUANG3⇑
  1. 1Program in Translational Medicine, National Chung Hsing University, Taichung, Taiwan, R.O.C.;
  2. 2Hemato-Oncology Division Department of Internal Medicine, Changhua Christian Hospital, Changhua, Taiwan, R.O.C.;
  3. 3Hematology & Oncology Research Laboratory, Changhua Christian Hospital, Changhua, Taiwan, R.O.C.
  1. Correspondence to: Ying-Chih Huang, Hematology & Oncology Research Laboratory, Changhua Christian Hospital, No.235 Shi-Guan Rd., Changhua, 50006, Taiwan, R.O.C. Tel: +886 47238595 ext 4961, e-mail: 181550{at}cch.org.tw
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Anticancer Research: 44 (3)
Anticancer Research
Vol. 44, Issue 3
March 2024
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Azacitidine–Hesperetin Combination Induces S-phase Cell Cycle Arrest and Apoptosis in Human Leukemia Cells
KUAN-MING LAI, RUO-HAN TSENG, YU-HUNG SHIH, YING-CHIH HUANG
Anticancer Research Mar 2024, 44 (3) 1033-1044; DOI: 10.21873/anticanres.16898

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Azacitidine–Hesperetin Combination Induces S-phase Cell Cycle Arrest and Apoptosis in Human Leukemia Cells
KUAN-MING LAI, RUO-HAN TSENG, YU-HUNG SHIH, YING-CHIH HUANG
Anticancer Research Mar 2024, 44 (3) 1033-1044; DOI: 10.21873/anticanres.16898
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Keywords

  • leukemia
  • azacitidine
  • hesperetin
  • apoptosis
  • molecular mechanisms
  • MAPK pathway
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