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Research ArticleExperimental Studies

Chlorhexidine Dihydrochloride Shows Anti-tumor Effects in Desmoid Tumors and Colorectal Cancer

HYERAN SHIN, YONGHYO KIM, YEHYEONG LEE, JISOO KIM, YEONG CHAN RYU, DONG-WOO KANG, TAE IL KIM and YONG-HEE CHO
Anticancer Research December 2024, 44 (12) 5435-5443; DOI: https://doi.org/10.21873/anticanres.17369
HYERAN SHIN
1Drug Discovery Platform Research Center, Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea;
2Department of Biotechnology, Yonsei University, Seoul, Republic of Korea;
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YONGHYO KIM
1Drug Discovery Platform Research Center, Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea;
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YEHYEONG LEE
1Drug Discovery Platform Research Center, Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea;
3Department of Medicinal Chemistry and Pharmacology, University of Science and Technology (UST), Daejeon, Republic of Korea;
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JISOO KIM
1Drug Discovery Platform Research Center, Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea;
3Department of Medicinal Chemistry and Pharmacology, University of Science and Technology (UST), Daejeon, Republic of Korea;
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YEONG CHAN RYU
4Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea;
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DONG-WOO KANG
5Medpacto Inc., Seoul, Republic of Korea;
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TAE IL KIM
6Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea
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YONG-HEE CHO
1Drug Discovery Platform Research Center, Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea;
2Department of Biotechnology, Yonsei University, Seoul, Republic of Korea;
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  • For correspondence: y-hcho@krict.re.kr
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Article Information

vol. 44 no. 12 5435-5443
DOI 
https://doi.org/10.21873/anticanres.17369
PubMed 
39626930

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received October 27, 2024
  • Revision received November 2, 2024
  • Accepted November 4, 2024
  • Published online December 2, 2024.

Copyright & Usage 
Copyright © 2024 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. HYERAN SHIN1,2,*,
  2. YONGHYO KIM1,*,
  3. YEHYEONG LEE1,3,
  4. JISOO KIM1,3,
  5. YEONG CHAN RYU4,
  6. DONG-WOO KANG5,
  7. TAE IL KIM6 and
  8. YONG-HEE CHO1,2⇑
  1. 1Drug Discovery Platform Research Center, Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea;
  2. 2Department of Biotechnology, Yonsei University, Seoul, Republic of Korea;
  3. 3Department of Medicinal Chemistry and Pharmacology, University of Science and Technology (UST), Daejeon, Republic of Korea;
  4. 4Department of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea;
  5. 5Medpacto Inc., Seoul, Republic of Korea;
  6. 6Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea
  1. Correspondence to: Yong-Hee Cho, Drug Discovery Platform Research Center, Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon 34114, Republic of Korea. Tel: +82 428607419, e-mail: y-hcho{at}krict.re.kr
  1. ↵* These Authors contributed equally to this study.

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Chlorhexidine Dihydrochloride Shows Anti-tumor Effects in Desmoid Tumors and Colorectal Cancer
HYERAN SHIN, YONGHYO KIM, YEHYEONG LEE, JISOO KIM, YEONG CHAN RYU, DONG-WOO KANG, TAE IL KIM, YONG-HEE CHO
Anticancer Research Dec 2024, 44 (12) 5435-5443; DOI: 10.21873/anticanres.17369

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Chlorhexidine Dihydrochloride Shows Anti-tumor Effects in Desmoid Tumors and Colorectal Cancer
HYERAN SHIN, YONGHYO KIM, YEHYEONG LEE, JISOO KIM, YEONG CHAN RYU, DONG-WOO KANG, TAE IL KIM, YONG-HEE CHO
Anticancer Research Dec 2024, 44 (12) 5435-5443; DOI: 10.21873/anticanres.17369
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Keywords

  • Desmoid tumors
  • colorectal cancer
  • chlorhexidine dihydrochloride
  • anti-tumor therapy
  • anti-cancer therapy
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