Peptide L13S Derived from the BRN2 POU Domain Reduces Metastasis In Vivo and Inhibits Cell Migration and Invasion In Vitro

MARIA CAROLINA MARIANO CESAR; RENATO ARRUDA MORTARA; VICTÓRIA SANTOS SOUZA; VITORIA RODRIGUES GUIMARAES ALVES; THAYSA PASCHOALIN; MARCO ANTONIO SOUFEN; GUILHERME MENDES DE FREITAS; FERNANDA FERNANDES MIRANDA DA CUNHA; DAYANE BATISTA TADA; ANDREY SENOS DOBROFF; DENISE COSTA ARRUDA

doi:10.21873/anticanres.16789

Research ArticleExperimental Studies

Peptide L13S Derived from the BRN2 POU Domain Reduces Metastasis In Vivo and Inhibits Cell Migration and Invasion In Vitro

MARIA CAROLINA MARIANO CESAR, RENATO ARRUDA MORTARA, VICTÓRIA SANTOS SOUZA, VITORIA RODRIGUES GUIMARAES ALVES, THAYSA PASCHOALIN, MARCO ANTONIO SOUFEN, GUILHERME MENDES DE FREITAS, FERNANDA FERNANDES MIRANDA DA CUNHA, DAYANE BATISTA TADA, ANDREY SENOS DOBROFF and DENISE COSTA ARRUDA

Anticancer Research January 2024, 44 (1) 71-84; DOI: https://doi.org/10.21873/anticanres.16789

MARIA CAROLINA MARIANO CESAR

1Núcleo Integrado de Biotecnologia, Universidade de Mogi das Cruzes, Mogi das Cruzes, SP, Brazil;

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RENATO ARRUDA MORTARA

2Departamento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de São Paulo, São Paulo, SP, Brazil;

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VICTÓRIA SANTOS SOUZA

1Núcleo Integrado de Biotecnologia, Universidade de Mogi das Cruzes, Mogi das Cruzes, SP, Brazil;

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VITORIA RODRIGUES GUIMARAES ALVES

1Núcleo Integrado de Biotecnologia, Universidade de Mogi das Cruzes, Mogi das Cruzes, SP, Brazil;

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THAYSA PASCHOALIN

3Departamento de Biofísica, Universidade Federal de São Paulo, São Paulo, SP, Brazil;

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MARCO ANTONIO SOUFEN

4Faculdade de Medicina da Universidade de Mogi das Cruzes, Universidade de Mogi das Cruzes, Mogi das Cruzes, SP, Brazil;

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GUILHERME MENDES DE FREITAS

1Núcleo Integrado de Biotecnologia, Universidade de Mogi das Cruzes, Mogi das Cruzes, SP, Brazil;

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FERNANDA FERNANDES MIRANDA DA CUNHA

1Núcleo Integrado de Biotecnologia, Universidade de Mogi das Cruzes, Mogi das Cruzes, SP, Brazil;

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DAYANE BATISTA TADA

5Instituto de Ciência e Tecnologia, Universidade Federal de São Paulo, São José dos Campos, SP, Brazil;

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ANDREY SENOS DOBROFF

6Division of Molecular Medicine, Department of Internal Medicine, University of New Mexico School of Medicine, Albuquerque, NM, U.S.A.;

7University of New Mexico Comprehensive Cancer Center, Albuquerque, NM, U.S.A.

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DENISE COSTA ARRUDA

1Núcleo Integrado de Biotecnologia, Universidade de Mogi das Cruzes, Mogi das Cruzes, SP, Brazil;

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For correspondence: denisearr@gmail.com

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Peptide L13S Derived from the BRN2 POU Domain Reduces Metastasis In Vivo and Inhibits Cell Migration and Invasion In Vitro

Anticancer Research Jan 2024, 44 (1) 71-84; DOI: 10.21873/anticanres.16789

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Peptide L13S Derived from the BRN2 POU Domain Reduces Metastasis In Vivo and Inhibits Cell Migration and Invasion In Vitro

Anticancer Research Jan 2024, 44 (1) 71-84; DOI: 10.21873/anticanres.16789

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Keywords

peptide
BRN2
POU domain
Melanoma
internalization
migration
invasion
metastatic model

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