Lymph Node Metastasis in Extraperitoneal Rectal Cancer After Neoadjuvant Therapy: An Unsolved Problem?

ALICE LA FRANCA; EDOARDO MARIA MUTTILLO; ISABELLA MADAFFARI; FANNY MASSIMI; GIUSEPPE LONGO; ALICE CECCACCI; ILARIA ANGELICONE; FLAVIA DE GIACOMO; ISABELLA SPERDUTI; GENOVEFFA BALDUCCI; MATTIA FALCHETTO OSTI; PAOLO MERCANTINI

doi:10.21873/anticanres.16450

Research ArticleClinical Studies

Lymph Node Metastasis in Extraperitoneal Rectal Cancer After Neoadjuvant Therapy: An Unsolved Problem?

ALICE LA FRANCA, EDOARDO MARIA MUTTILLO, ISABELLA MADAFFARI, FANNY MASSIMI, GIUSEPPE LONGO, ALICE CECCACCI, ILARIA ANGELICONE, FLAVIA DE GIACOMO, ISABELLA SPERDUTI, GENOVEFFA BALDUCCI, MATTIA FALCHETTO OSTI and PAOLO MERCANTINI

Anticancer Research June 2023, 43 (6) 2813-2820; DOI: https://doi.org/10.21873/anticanres.16450

ALICE LA FRANCA

1Department of Medical Surgical Science and Translational Medicine, Sant’ Andrea Hospital, Sapienza University of Rome, Rome, Italy;

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EDOARDO MARIA MUTTILLO

1Department of Medical Surgical Science and Translational Medicine, Sant’ Andrea Hospital, Sapienza University of Rome, Rome, Italy;

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For correspondence: edoardomaria.muttillo{at}uniroma1.it

ISABELLA MADAFFARI

1Department of Medical Surgical Science and Translational Medicine, Sant’ Andrea Hospital, Sapienza University of Rome, Rome, Italy;

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FANNY MASSIMI

1Department of Medical Surgical Science and Translational Medicine, Sant’ Andrea Hospital, Sapienza University of Rome, Rome, Italy;

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GIUSEPPE LONGO

1Department of Medical Surgical Science and Translational Medicine, Sant’ Andrea Hospital, Sapienza University of Rome, Rome, Italy;

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ALICE CECCACCI

1Department of Medical Surgical Science and Translational Medicine, Sant’ Andrea Hospital, Sapienza University of Rome, Rome, Italy;

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ILARIA ANGELICONE

2Radiotherapy Oncology, Sant’ Andrea Hospital, Sapienza University of Rome, Rome, Italy;

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FLAVIA DE GIACOMO

2Radiotherapy Oncology, Sant’ Andrea Hospital, Sapienza University of Rome, Rome, Italy;

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ISABELLA SPERDUTI

3Biostatistical Unit – Clinical Trials Center, IRCCS Regina Elena National Cancer Institute, Rome, Italy

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GENOVEFFA BALDUCCI

1Department of Medical Surgical Science and Translational Medicine, Sant’ Andrea Hospital, Sapienza University of Rome, Rome, Italy;

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MATTIA FALCHETTO OSTI

2Radiotherapy Oncology, Sant’ Andrea Hospital, Sapienza University of Rome, Rome, Italy;

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PAOLO MERCANTINI

1Department of Medical Surgical Science and Translational Medicine, Sant’ Andrea Hospital, Sapienza University of Rome, Rome, Italy;

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Figure 1.
Kaplan-Meier curves of disease-free survival according to lymph nodal staging (pN).

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Anticancer Research

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June 2023

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Lymph Node Metastasis in Extraperitoneal Rectal Cancer After Neoadjuvant Therapy: An Unsolved Problem?

Anticancer Research Jun 2023, 43 (6) 2813-2820; DOI: 10.21873/anticanres.16450

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Lymph Node Metastasis in Extraperitoneal Rectal Cancer After Neoadjuvant Therapy: An Unsolved Problem?

Anticancer Research Jun 2023, 43 (6) 2813-2820; DOI: 10.21873/anticanres.16450

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Keywords

Rectal cancer
organ-sparing surgery
lymph node metastasis
watch and wait
neoadjuvant chemoradiotherapy
complete pathological response
clinical complete response

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