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Research ArticleExperimental Studies

11-epi-Sinulariolide Acetate-induced Apoptosis in Oral Cancer Cells Is Regulated by FOXO Through Inhibition of PI3K/AKT Pathway

TING-SHOU CHANG, JEN-JIE LIN, KAI-CHUN CHENG, JUI-HSIN SU, YUN-YING SHE and YU-JEN WU
Anticancer Research June 2023, 43 (6) 2625-2634; DOI: https://doi.org/10.21873/anticanres.16429
TING-SHOU CHANG
1Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, R.O.C.;
2School of Medicine, National Defense Medical Center, Taipei, Taiwan, R.O.C.;
3Institute of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan, R.O.C.;
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JEN-JIE LIN
4Yu Jun Biotechnology Co., Ltd., Kaohsiung, Taiwan, R.O.C.;
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KAI-CHUN CHENG
5Department of Ophthalmology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung, Taiwan, R.O.C.;
6Department of Ophthalmology, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, R.O.C.;
7Department of Ophthalmology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, R.O.C.;
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JUI-HSIN SU
8National Museum of Marine Biology and Aquarium, Pingtung, Taiwan, R.O.C.;
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YUN-YING SHE
1Department of Otolaryngology-Head and Neck Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, R.O.C.;
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YU-JEN WU
4Yu Jun Biotechnology Co., Ltd., Kaohsiung, Taiwan, R.O.C.;
9Department of Food and Nutrition, Meiho University, Pingtung, Taiwan, R.O.C.
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  • For correspondence: x00002180@meiho.edu.tw
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Anticancer Research: 43 (6)
Anticancer Research
Vol. 43, Issue 6
June 2023
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11-epi-Sinulariolide Acetate-induced Apoptosis in Oral Cancer Cells Is Regulated by FOXO Through Inhibition of PI3K/AKT Pathway
TING-SHOU CHANG, JEN-JIE LIN, KAI-CHUN CHENG, JUI-HSIN SU, YUN-YING SHE, YU-JEN WU
Anticancer Research Jun 2023, 43 (6) 2625-2634; DOI: 10.21873/anticanres.16429

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11-epi-Sinulariolide Acetate-induced Apoptosis in Oral Cancer Cells Is Regulated by FOXO Through Inhibition of PI3K/AKT Pathway
TING-SHOU CHANG, JEN-JIE LIN, KAI-CHUN CHENG, JUI-HSIN SU, YUN-YING SHE, YU-JEN WU
Anticancer Research Jun 2023, 43 (6) 2625-2634; DOI: 10.21873/anticanres.16429
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Keywords

  • 11-epi-sinulariolide acetate
  • oral squamous cell carcinoma
  • Sinularia flexibilis
  • PI3K/AKT/FOXO
  • apoptosis
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