Differential Effects of Anti-PD-1/PD-L1 Checkpoint Inhibitors on Adhesion Molecules and Cytokine Secretion by THP-1 Monocytes

EVA PROBST; KLAAS F. FRANZEN; CHRISTIAN IDEL; KIRSTIN PLÖTZE-MARTIN; JONAS FLECKNER; DIRK RADES; SABINE BOHNET; KARL-LUDWIG BRUCHHAGE; RALPH PRIES

doi:10.21873/anticanres.16412

Research ArticleExperimental Studies

Differential Effects of Anti-PD-1/PD-L1 Checkpoint Inhibitors on Adhesion Molecules and Cytokine Secretion by THP-1 Monocytes

EVA PROBST, KLAAS F. FRANZEN, CHRISTIAN IDEL, KIRSTIN PLÖTZE-MARTIN, JONAS FLECKNER, DIRK RADES, SABINE BOHNET, KARL-LUDWIG BRUCHHAGE and RALPH PRIES

Anticancer Research June 2023, 43 (6) 2445-2454; DOI: https://doi.org/10.21873/anticanres.16412

EVA PROBST

1Department of Medical Clinic III, University of Lübeck, Lübeck, Germany

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KLAAS F. FRANZEN

1Department of Medical Clinic III, University of Lübeck, Lübeck, Germany

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CHRISTIAN IDEL

2Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University of Lübeck, Lübeck, Germany

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KIRSTIN PLÖTZE-MARTIN

2Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University of Lübeck, Lübeck, Germany

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JONAS FLECKNER

2Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University of Lübeck, Lübeck, Germany

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DIRK RADES

3Department of Radiation Oncology, University of Lübeck, Lübeck, Germany

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SABINE BOHNET

1Department of Medical Clinic III, University of Lübeck, Lübeck, Germany

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KARL-LUDWIG BRUCHHAGE

2Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University of Lübeck, Lübeck, Germany

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RALPH PRIES

2Department of Oto-Rhino-Laryngology and Head and Neck Surgery, University of Lübeck, Lübeck, Germany

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For correspondence: ralph.pries{at}uksh.de

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Anticancer Research

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June 2023

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Differential Effects of Anti-PD-1/PD-L1 Checkpoint Inhibitors on Adhesion Molecules and Cytokine Secretion by THP-1 Monocytes

EVA PROBST, KLAAS F. FRANZEN, CHRISTIAN IDEL, KIRSTIN PLÖTZE-MARTIN, JONAS FLECKNER, DIRK RADES, SABINE BOHNET, KARL-LUDWIG BRUCHHAGE, RALPH PRIES

Anticancer Research Jun 2023, 43 (6) 2445-2454; DOI: 10.21873/anticanres.16412

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Differential Effects of Anti-PD-1/PD-L1 Checkpoint Inhibitors on Adhesion Molecules and Cytokine Secretion by THP-1 Monocytes

EVA PROBST, KLAAS F. FRANZEN, CHRISTIAN IDEL, KIRSTIN PLÖTZE-MARTIN, JONAS FLECKNER, DIRK RADES, SABINE BOHNET, KARL-LUDWIG BRUCHHAGE, RALPH PRIES

Anticancer Research Jun 2023, 43 (6) 2445-2454; DOI: 10.21873/anticanres.16412

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Keywords

immunotherapy
anti-PD-1/PD-L1 checkpoint inhibitors
monocytes
adhesion molecules
cytokines

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