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Research ArticleClinical Studies
Open Access

CD8-positive Tumor-infiltrating Lymphocytes and Prognosis in Radiotherapy for Uterine Cervical Squamous Cell Carcinoma

YUHEI MIYASAKA, YUYA YOSHIMOTO, KEN ANDO, KAZUTOSHI MURATA, DAISUKE IRIE, HIRO SATO, SHIN-EI NODA, HAYATO IKOTA, TAKASHI NAKANO, HIDEAKI YOKOO and TATSUYA OHNO
Anticancer Research May 2023, 43 (5) 2077-2084; DOI: https://doi.org/10.21873/anticanres.16368
YUHEI MIYASAKA
1Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan;
2Gunma University Heavy Ion Medical Center, Maebashi, Japan;
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  • For correspondence: y.miyasaka{at}gunma-u.ac.jp
YUYA YOSHIMOTO
1Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan;
3Department of Radiation Oncology, Fukushima Medical University School of Medicine, Fukushima, Japan;
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KEN ANDO
1Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan;
2Gunma University Heavy Ion Medical Center, Maebashi, Japan;
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KAZUTOSHI MURATA
4QST Hospital, National Institutes for Quantum and Radiological Science and Technology, Inage-ku, Japan;
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DAISUKE IRIE
1Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan;
2Gunma University Heavy Ion Medical Center, Maebashi, Japan;
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HIRO SATO
1Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan;
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SHIN-EI NODA
5Department of Radiation Oncology, Saitama Medical University International Medical Center, Hidaka, Japan;
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HAYATO IKOTA
6Department of Diagnostic Pathology, Gunma University Hospital, Maebashi, Japan;
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TAKASHI NAKANO
1Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan;
7Quantum Life and Medical Science Directorate, National Institute for Quantum Radiological Science and Technology, Inage-ku, Japan;
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HIDEAKI YOKOO
6Department of Diagnostic Pathology, Gunma University Hospital, Maebashi, Japan;
8Department of Human Pathology, Gunma University Graduate School of Medicine, Maebashi, Japan
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TATSUYA OHNO
1Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan;
2Gunma University Heavy Ion Medical Center, Maebashi, Japan;
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Article Information

vol. 43 no. 5 2077-2084
DOI 
https://doi.org/10.21873/anticanres.16368
PubMed 
37097697

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received February 8, 2023
  • Revision received February 23, 2023
  • Accepted February 24, 2023
  • Published online April 25, 2023.

Copyright & License 
Copyright © 2023 The Author(s). Published by the International Institute of Anticancer Research. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY-NC-ND) 4.0 international license (https://creativecommons.org/licenses/by-nc-nd/4.0).

Author Information

  1. YUHEI MIYASAKA1,2⇑,
  2. YUYA YOSHIMOTO1,3,
  3. KEN ANDO1,2,
  4. KAZUTOSHI MURATA4,
  5. DAISUKE IRIE1,2,
  6. HIRO SATO1,
  7. SHIN-EI NODA5,
  8. HAYATO IKOTA6,
  9. TAKASHI NAKANO1,7,
  10. HIDEAKI YOKOO6,8 and
  11. TATSUYA OHNO1,2
  1. 1Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan;
  2. 2Gunma University Heavy Ion Medical Center, Maebashi, Japan;
  3. 3Department of Radiation Oncology, Fukushima Medical University School of Medicine, Fukushima, Japan;
  4. 4QST Hospital, National Institutes for Quantum and Radiological Science and Technology, Inage-ku, Japan;
  5. 5Department of Radiation Oncology, Saitama Medical University International Medical Center, Hidaka, Japan;
  6. 6Department of Diagnostic Pathology, Gunma University Hospital, Maebashi, Japan;
  7. 7Quantum Life and Medical Science Directorate, National Institute for Quantum Radiological Science and Technology, Inage-ku, Japan;
  8. 8Department of Human Pathology, Gunma University Graduate School of Medicine, Maebashi, Japan
  1. Correspondence to: Yuhei Miyasaka, MD, Ph.D., Department of Radiation Oncology, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma 371-8511, Japan. Tel: +81 272208383, Fax: +81 272208397, e-mail: y.miyasaka{at}gunma-u.ac.jp
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CD8-positive Tumor-infiltrating Lymphocytes and Prognosis in Radiotherapy for Uterine Cervical Squamous Cell Carcinoma
YUHEI MIYASAKA, YUYA YOSHIMOTO, KEN ANDO, KAZUTOSHI MURATA, DAISUKE IRIE, HIRO SATO, SHIN-EI NODA, HAYATO IKOTA, TAKASHI NAKANO, HIDEAKI YOKOO, TATSUYA OHNO
Anticancer Research May 2023, 43 (5) 2077-2084; DOI: 10.21873/anticanres.16368

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CD8-positive Tumor-infiltrating Lymphocytes and Prognosis in Radiotherapy for Uterine Cervical Squamous Cell Carcinoma
YUHEI MIYASAKA, YUYA YOSHIMOTO, KEN ANDO, KAZUTOSHI MURATA, DAISUKE IRIE, HIRO SATO, SHIN-EI NODA, HAYATO IKOTA, TAKASHI NAKANO, HIDEAKI YOKOO, TATSUYA OHNO
Anticancer Research May 2023, 43 (5) 2077-2084; DOI: 10.21873/anticanres.16368
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Keywords

  • cervical cancer
  • squamous cell carcinoma
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  • CD8
  • tumor-infiltrating lymphocytes
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