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Research ArticleExperimental Studies

TU-100 Antagonizes the M2 Polarization Phenotype of Macrophages in the Tumor Microenvironment by Suppressing the TLR4/NF-GraphicB/STAT3 Axis

SHUHAI CHEN, YUJI MORINE, YU SAITO, SHINICHIRO YAMADA, HIROKI TERAOKU, TETSUYA IKEMOTO and MITSUO SHIMADA
Anticancer Research May 2023, 43 (5) 1985-1992; DOI: https://doi.org/10.21873/anticanres.16359
SHUHAI CHEN
Department of Surgery, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan
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YUJI MORINE
Department of Surgery, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan
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  • For correspondence: ymorine@tokushima-u.ac.jp
YU SAITO
Department of Surgery, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan
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SHINICHIRO YAMADA
Department of Surgery, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan
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HIROKI TERAOKU
Department of Surgery, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan
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TETSUYA IKEMOTO
Department of Surgery, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan
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MITSUO SHIMADA
Department of Surgery, Institute of Biomedical Sciences, Tokushima University, Tokushima, Japan
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Anticancer Research: 43 (5)
Anticancer Research
Vol. 43, Issue 5
May 2023
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TU-100 Antagonizes the M2 Polarization Phenotype of Macrophages in the Tumor Microenvironment by Suppressing the TLR4/NF-GraphicB/STAT3 Axis
SHUHAI CHEN, YUJI MORINE, YU SAITO, SHINICHIRO YAMADA, HIROKI TERAOKU, TETSUYA IKEMOTO, MITSUO SHIMADA
Anticancer Research May 2023, 43 (5) 1985-1992; DOI: 10.21873/anticanres.16359

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TU-100 Antagonizes the M2 Polarization Phenotype of Macrophages in the Tumor Microenvironment by Suppressing the TLR4/NF-GraphicB/STAT3 Axis
SHUHAI CHEN, YUJI MORINE, YU SAITO, SHINICHIRO YAMADA, HIROKI TERAOKU, TETSUYA IKEMOTO, MITSUO SHIMADA
Anticancer Research May 2023, 43 (5) 1985-1992; DOI: 10.21873/anticanres.16359
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Keywords

  • tumor-associated macrophages
  • M2 polarization
  • tumor microenvironment
  • toll-like receptor 4
  • nuclear factor-B
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