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Research ArticleClinical Studies

Life-threatening Airway Complication After Radioactive Iodine Treatment: A Case Report and Review of the Literature

FREDRIK LANDSTRÖM, JANA SANDBERG and JOHAN REIZENSTEIN
Anticancer Research April 2023, 43 (4) 1853-1855; DOI: https://doi.org/10.21873/anticanres.16339
FREDRIK LANDSTRÖM
1Department of Otolaryngology, Örebro University Hospital, Örebro, Sweden;
2Örebro University, Örebro, Sweden;
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  • For correspondence: fredrik.landstrom@regionorebrolan.se
JANA SANDBERG
3Department of Oncology, Örebro University Hospital, Örebro, Sweden
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JOHAN REIZENSTEIN
3Department of Oncology, Örebro University Hospital, Örebro, Sweden
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Abstract

Background/Aim: Radioactive iodine (RAI) treatment is a cornerstone of treatment of differentiated thyroid carcinoma. Although serious RAI-related complications are uncommon, there have been reports of airway emergencies. Here, a life-threatening airway complication after RAI treatment is reported and previously reported cases are reviewed. Case Report: A 79-year old man with Hürthle cell carcinoma and a remnant thyroid lobe after surgery developed an edema compromising the airway two days after receiving radioactive iodine treatment. An emergency awake intubation and tracheostomy were performed. He could be successfully de-cannulated 17 days later with no long-term complications. Conclusion: Although rare, life-threatening airway complications after radioactive iodine treatment, especially with high dose treatment in patients with remaining thyroid tissue, can occur and these patients should be supervised where these complications can be managed.

Key Words:
  • Radioactive iodine
  • thyroid carcinoma
  • airway emergency
  • Received January 23, 2023.
  • Revision received February 2, 2023.
  • Accepted February 3, 2023.
  • Copyright © 2023 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
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Anticancer Research: 43 (4)
Anticancer Research
Vol. 43, Issue 4
April 2023
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Life-threatening Airway Complication After Radioactive Iodine Treatment: A Case Report and Review of the Literature
FREDRIK LANDSTRÖM, JANA SANDBERG, JOHAN REIZENSTEIN
Anticancer Research Apr 2023, 43 (4) 1853-1855; DOI: 10.21873/anticanres.16339

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Life-threatening Airway Complication After Radioactive Iodine Treatment: A Case Report and Review of the Literature
FREDRIK LANDSTRÖM, JANA SANDBERG, JOHAN REIZENSTEIN
Anticancer Research Apr 2023, 43 (4) 1853-1855; DOI: 10.21873/anticanres.16339
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Keywords

  • Radioactive iodine
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