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Research ArticleExperimental Studies

A Standardized Extract of Cultured Lentinula edodes mycelia Up-regulates COX-2 in Inflammation-related Malignant Progressive Fibrosarcoma Cell Clone QRsP-11

TAKAO KITAGAWA, SHAJEDUL ISLAM, BYRON BARON, KAZUHIRO TOKUDA, DURGA PAUDEL, TOHRU OHTA, KOJI NAKAGAWA, MASANOBU KOBAYASHI, FUTOSHI OKADA and YASUHIRO KURAMITSU
Anticancer Research March 2023, 43 (3) 1239-1244; DOI: https://doi.org/10.21873/anticanres.16270
TAKAO KITAGAWA
1Advanced Research Promotion Center, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan;
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SHAJEDUL ISLAM
1Advanced Research Promotion Center, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan;
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BYRON BARON
2Centre for Molecular Medicine and Biobanking, University of Malta, Msida, Malta;
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KAZUHIRO TOKUDA
3Graduate School of Health and Welfare, Yamaguchi Prefectural University, Yamaguchi, Japan;
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DURGA PAUDEL
1Advanced Research Promotion Center, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan;
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TOHRU OHTA
1Advanced Research Promotion Center, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan;
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KOJI NAKAGAWA
1Advanced Research Promotion Center, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan;
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MASANOBU KOBAYASHI
1Advanced Research Promotion Center, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan;
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FUTOSHI OKADA
4Division of Experimental Pathology, Faculty of Medicine, Tottori University, Yonago, Japan
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YASUHIRO KURAMITSU
1Advanced Research Promotion Center, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan;
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  • For correspondence: climates@hoku-iryo-u.ac.jp
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Article Information

vol. 43 no. 3 1239-1244
DOI 
https://doi.org/10.21873/anticanres.16270
PubMed 
36854525

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received September 29, 2022
  • Revision received October 25, 2022
  • Accepted October 31, 2022
  • Published online February 28, 2023.

Copyright & Usage 
Copyright © 2023 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. TAKAO KITAGAWA1,
  2. SHAJEDUL ISLAM1,
  3. BYRON BARON2,
  4. KAZUHIRO TOKUDA3,
  5. DURGA PAUDEL1,
  6. TOHRU OHTA1,
  7. KOJI NAKAGAWA1,
  8. MASANOBU KOBAYASHI1,
  9. FUTOSHI OKADA4 and
  10. YASUHIRO KURAMITSU1⇑
  1. 1Advanced Research Promotion Center, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Japan;
  2. 2Centre for Molecular Medicine and Biobanking, University of Malta, Msida, Malta;
  3. 3Graduate School of Health and Welfare, Yamaguchi Prefectural University, Yamaguchi, Japan;
  4. 4Division of Experimental Pathology, Faculty of Medicine, Tottori University, Yonago, Japan
  1. Correspondence to: Yasuhiro Kuramitsu, MD, Ph.D., Advanced Research Promotion Center, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari-Tobetsu, Hokkaido 061-0293, Japan. Tel +81 133231630, e-mail: climates{at}hoku-iryo-u.ac.jp
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A Standardized Extract of Cultured Lentinula edodes mycelia Up-regulates COX-2 in Inflammation-related Malignant Progressive Fibrosarcoma Cell Clone QRsP-11
TAKAO KITAGAWA, SHAJEDUL ISLAM, BYRON BARON, KAZUHIRO TOKUDA, DURGA PAUDEL, TOHRU OHTA, KOJI NAKAGAWA, MASANOBU KOBAYASHI, FUTOSHI OKADA, YASUHIRO KURAMITSU
Anticancer Research Mar 2023, 43 (3) 1239-1244; DOI: 10.21873/anticanres.16270

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A Standardized Extract of Cultured Lentinula edodes mycelia Up-regulates COX-2 in Inflammation-related Malignant Progressive Fibrosarcoma Cell Clone QRsP-11
TAKAO KITAGAWA, SHAJEDUL ISLAM, BYRON BARON, KAZUHIRO TOKUDA, DURGA PAUDEL, TOHRU OHTA, KOJI NAKAGAWA, MASANOBU KOBAYASHI, FUTOSHI OKADA, YASUHIRO KURAMITSU
Anticancer Research Mar 2023, 43 (3) 1239-1244; DOI: 10.21873/anticanres.16270
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Keywords

  • COX-2
  • malignant progression
  • inflammation
  • fibrosarcoma
  • AHCC®
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