Streptonigrin Mitigates Lung Cancer-induced Cachexia by Suppressing TCF4/TWIST1-induced PTHLH Expression

XUE-QUAN FANG; SEONGHOON LEE; YOUNG-SEON KIM; GA EUL HAN; CHANG-HOON LIM; JI-HONG LIM

doi:10.21873/anticanres.16260

Research ArticleExperimental Studies

Streptonigrin Mitigates Lung Cancer-induced Cachexia by Suppressing TCF4/TWIST1-induced PTHLH Expression

XUE-QUAN FANG, SEONGHOON LEE, YOUNG-SEON KIM, GA EUL HAN, CHANG-HOON LIM and JI-HONG LIM

Anticancer Research March 2023, 43 (3) 1149-1157; DOI: https://doi.org/10.21873/anticanres.16260

XUE-QUAN FANG

1Department of Medicinal Biosciences, College of Biomedical & Health Science, Konkuk University, Chungju, Republic of Korea;

2Department of Applied Life Science, Graduate School, BK21 Program, Konkuk University, Chungju, Republic of Korea;

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SEONGHOON LEE

1Department of Medicinal Biosciences, College of Biomedical & Health Science, Konkuk University, Chungju, Republic of Korea;

2Department of Applied Life Science, Graduate School, BK21 Program, Konkuk University, Chungju, Republic of Korea;

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YOUNG-SEON KIM

2Department of Applied Life Science, Graduate School, BK21 Program, Konkuk University, Chungju, Republic of Korea;

3Jung-Ang Microbe Research Institute (JM), Heungdeok-gu, Cheongju, Republic of Korea;

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GA EUL HAN

1Department of Medicinal Biosciences, College of Biomedical & Health Science, Konkuk University, Chungju, Republic of Korea;

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CHANG-HOON LIM

1Department of Medicinal Biosciences, College of Biomedical & Health Science, Konkuk University, Chungju, Republic of Korea;

2Department of Applied Life Science, Graduate School, BK21 Program, Konkuk University, Chungju, Republic of Korea;

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JI-HONG LIM

1Department of Medicinal Biosciences, College of Biomedical & Health Science, Konkuk University, Chungju, Republic of Korea;

2Department of Applied Life Science, Graduate School, BK21 Program, Konkuk University, Chungju, Republic of Korea;

4Center for Metabolic Diseases, Konkuk University, Chungju, Republic of Korea

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For correspondence: jhlim@kku.ac.kr

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Streptonigrin Mitigates Lung Cancer-induced Cachexia by Suppressing TCF4/TWIST1-induced PTHLH Expression

XUE-QUAN FANG, SEONGHOON LEE, YOUNG-SEON KIM, GA EUL HAN, CHANG-HOON LIM, JI-HONG LIM

Anticancer Research Mar 2023, 43 (3) 1149-1157; DOI: 10.21873/anticanres.16260

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Streptonigrin Mitigates Lung Cancer-induced Cachexia by Suppressing TCF4/TWIST1-induced PTHLH Expression

XUE-QUAN FANG, SEONGHOON LEE, YOUNG-SEON KIM, GA EUL HAN, CHANG-HOON LIM, JI-HONG LIM

Anticancer Research Mar 2023, 43 (3) 1149-1157; DOI: 10.21873/anticanres.16260

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Keywords

lung cancer
cachexia
TCF4
TWIST1
PTHLH
streptonigrin

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