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Research ArticleExperimental Studies

5-Oxoproline Enhances 4-Hydroxytamoxifen-induced Cytotoxicity by Increasing Oxidative Stress in MCF-7 Breast Cancer Cells

TAKANOBU NADAI, KATSUYA NARUMI, YUTO MUKAI, HINATA UEDA, AYAKO FURUGEN, YOSHITAKA SAITO and MASAKI KOBAYASHI
Anticancer Research March 2023, 43 (3) 1113-1120; DOI: https://doi.org/10.21873/anticanres.16256
TAKANOBU NADAI
1Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan;
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KATSUYA NARUMI
1Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan;
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  • For correspondence: narumik{at}pharm.hokudai.ac.jp
YUTO MUKAI
1Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan;
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HINATA UEDA
1Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan;
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AYAKO FURUGEN
1Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan;
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YOSHITAKA SAITO
2Department of Pharmacy, Hokkaido University Hospital, Sapporo, Japan
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MASAKI KOBAYASHI
1Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan;
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  • For correspondence: masaki{at}pharm.hokudai.ac.jp
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Article Information

vol. 43 no. 3 1113-1120
DOI 
https://doi.org/10.21873/anticanres.16256
PMID 
36854517

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received December 23, 2022
  • Revision received January 3, 2023
  • Accepted January 10, 2023
  • Published online February 28, 2023.

Copyright & Usage 
Copyright © 2023 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. TAKANOBU NADAI1,#,
  2. KATSUYA NARUMI1⇑,
  3. YUTO MUKAI1,
  4. HINATA UEDA1,
  5. AYAKO FURUGEN1,
  6. YOSHITAKA SAITO2 and
  7. MASAKI KOBAYASHI1⇑
  1. 1Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan;
  2. 2Department of Pharmacy, Hokkaido University Hospital, Sapporo, Japan
  1. Correspondence to: Katsuya Narumi, Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12-jo, Nishi-6-chome, Kita-ku, Sapporo 060-0812, Japan. Tel: +81 117063771, e-mail: narumik{at}pharm.hokudai.ac.jp
  2. Correspondence to: Masaki Kobayashi, Laboratory of Clinical Pharmaceutics & Therapeutics, Division of Pharmasciences, Faculty of Pharmaceutical Sciences, Hokkaido University, Kita-12-jo, Nishi-6-chome, Kita-ku, Sapporo 060-0812, Japan. Tel: +81 117063770, e-mail: masaki{at}pharm.hokudai.ac.jp
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5-Oxoproline Enhances 4-Hydroxytamoxifen-induced Cytotoxicity by Increasing Oxidative Stress in MCF-7 Breast Cancer Cells
TAKANOBU NADAI, KATSUYA NARUMI, YUTO MUKAI, HINATA UEDA, AYAKO FURUGEN, YOSHITAKA SAITO, MASAKI KOBAYASHI
Anticancer Research Mar 2023, 43 (3) 1113-1120; DOI: 10.21873/anticanres.16256

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5-Oxoproline Enhances 4-Hydroxytamoxifen-induced Cytotoxicity by Increasing Oxidative Stress in MCF-7 Breast Cancer Cells
TAKANOBU NADAI, KATSUYA NARUMI, YUTO MUKAI, HINATA UEDA, AYAKO FURUGEN, YOSHITAKA SAITO, MASAKI KOBAYASHI
Anticancer Research Mar 2023, 43 (3) 1113-1120; DOI: 10.21873/anticanres.16256
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Keywords

  • Tamoxifen
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