About the Cover

Experimental Studies

• Open Access

  7,8-Diacetoxy-3-(4-methylsulfonylphenyl)-4-phenylcoumarin Induces ROS-dependent Cell Death in the A549 Human Lung Cancer Cell Line

  MUSILIYU A. MUSA and QUDUS KOLAWOLE

  Anticancer Research March 2023, 43 (3) 1001-1007; DOI: https://doi.org/10.21873/anticanres.16244
• Open Access

  Cyclodextrin Conjugated α-Bisabolol Suppresses FAK Phosphorylation and Induces Apoptosis in Pancreatic Cancer

  MIKIKO TAKEBAYASHI KANO, TOSHIO KOKURYO, TAISUKE BABA, KIMITOSHI YAMAZAKI, JUNPEI YAMAGUCHI, MASAKI SUNAGAWA, ATSUSHI OGURA, NOBUYUKI WATANABE, SHUNSUKE ONOE, KAZUSHI MIYATA, TAKASHI MIZUNO, KAY UEHARA, TSUYOSHI IGAMI, YUKIHIRO YOKOYAMA, TOMOKI EBATA and MASATO NAGINO

  Anticancer Research March 2023, 43 (3) 1009-1016; DOI: https://doi.org/10.21873/anticanres.16245
• Open Access

  Plasma Rhenium and Selenium Concentrations After Repeated Daily Oral Administration of Rhenium(I)-diselenoether in 4T1 Breast Tumor-bearing Mice

  PHILIPPE COLLERY, BERNHARD MICHALKE, MARIANNA LUCIO, DIDIER VARLET, JEAN-MARIE GUIGONIS, JEAN-CLAUDE SCIMECA, HEIDY SCHMID-ANTOMARCHI and ANNIE SCHMID-ALLIANA

  Anticancer Research March 2023, 43 (3) 1017-1023; DOI: https://doi.org/10.21873/anticanres.16246
• You have access

  Epigallocatechin Gallate Inhibits Cell Growth and Hedgehog Signalling in Human Rhabdomyosarcoma Cell Lines

  BENJAMIN F.B. MAYER, MATIAS J. STAGNO, JÖRG FUCHS, STEVEN W. WARMANN and EVI SCHMID

  Anticancer Research March 2023, 43 (3) 1025-1030; DOI: https://doi.org/10.21873/anticanres.16247
• You have access

  Modulatory Activity of the Copper Chelate, Copper N-(2-Hydroxy Acetophenone) Glycinate, in ABC-transporter-expressing Cell Lines

  EVA-MARIA HARTINGER, ANNE MAHRINGER, SOUMITRA KUMAR CHOUDHURI, GERT FRICKER and THOMAS EFFERTH

  Anticancer Research March 2023, 43 (3) 1031-1041; DOI: https://doi.org/10.21873/anticanres.16248
• You have access

  Successful Identification of a Novel Therapeutic Compound for Hepatocellular Carcinoma Through Screening of ADAM9 Inhibitors

  KEITA OGAWA, TETSUHIRO CHIBA, MASATO NAKAMURA, JUN ARAI, JIAQI ZHANG, YAOJIA MA, NA QIANG, JUNJIE AO, SAE YUMITA, TAKAMASA ISHINO, MOTOYASU KAN, TERUNAO IWANAGA, MIYUKI NAKAGAWA, KISAKO FUJIWARA, TAKAFUMI SAKUMA, HIROAKI KANZAKI, KEISUKE KOROKI, YUKO KUSAKABE, KAZUFUMI KOBAYASHI, NAOYA KANOGAWA, SOICHIRO KIYONO, TAKAYUKI KONDO, RYO NAKAGAWA, SADAHISA OGASAWARA, RYOSUKE MUROYAMA, SHINGO NAKAMOTO, TATSUO KANDA, HITOSHI MARUYAMA, JUN KATO, SHOJI MATSUMOTO, TAKAYOSHI ARAI, SHINICHIRO MOTOHASHI and NAOYA KATO

  Anticancer Research March 2023, 43 (3) 1043-1052; DOI: https://doi.org/10.21873/anticanres.16249
• You have access

  Specific Aptamer Functionalization of Dense Ceramic by Click Chemistry Towards Circulating Tumor Cells Apheresis

  GUISLAINE BARRIERE, MICHEL RIGAUD, CLEMENT ARRAT, HELOÏSE COLOMBI and EVELYNE POLI

  Anticancer Research March 2023, 43 (3) 1053-1064; DOI: https://doi.org/10.21873/anticanres.16250
• Open Access

  Atezolizumab Retains Cellular Binding to Programmed Death Ligand 1 Following Aerosolization via Mesh Nebulizer

  GINTARAS ZALESKIS, MARTYNAS TALAIKIS, DAINIUS CHARACIEJUS, VINCAS URBONAS, PAULIUS BOSAS, ADAS DARINSKAS, LAVIJA ZIBUTYTE, LUKAS SIMKUS, ZILVINAS SURVILA, JURGITA JURSENAITE and MARGARITA ZVIRBLE

  Anticancer Research March 2023, 43 (3) 1065-1072; DOI: https://doi.org/10.21873/anticanres.16251
• You have access

  Validation of EZH2 Inhibitor Efficiency in Anaplastic Thyroid Carcinoma Cell Lines

  HIROTAKA NAKAYAMA, NAO SAITO, RIKA KASAJIMA, NOBUYASU SUGANUMA, YASUSHI RINO, KATSUHIKO MASUDO, HARUHIKO YAMAZAKI, SOJI TODA, KAZUMASA SEKIHARA, HIROYUKI IWASAKI and DAISUKE HOSHINO

  Anticancer Research March 2023, 43 (3) 1073-1077; DOI: https://doi.org/10.21873/anticanres.16252
• You have access

  Chemokine (C-C motif) Ligand 2 Is Regulated Through the EGFR/Src Pathway in HER2-positive Breast Cancer Cells

  DAEUN YOU, HYUNGJOO KIM, YISUN JEONG, SUN YOUNG YOON, EUNJI LO, JEONG EON LEE and SANGMIN KIM

  Anticancer Research March 2023, 43 (3) 1079-1089; DOI: https://doi.org/10.21873/anticanres.16253
• You have access

  Isophysalin A Inhibits the Stemness of Breast Cancer Cells Possibly via Stat3 and IL-6 Signaling

  YU-CHAN KO, HACK SUN CHOI, SU-LIM KIM and DONG-SUN LEE

  Anticancer Research March 2023, 43 (3) 1091-1101; DOI: https://doi.org/10.21873/anticanres.16254
• You have access

  Low-dose Pimecrolimus, an FDA-approved Calcineurin Inhibitor, Sensitizes Drug-resistant Cancer Cells via Strong P-gp Inhibition

  JAE HYEON PARK, JI SUN LEE, JOO KYUNG SHIN, SWATI SHARMA, HYUNG SIK KIM and SUNGPIL YOON

  Anticancer Research March 2023, 43 (3) 1103-1112; DOI: https://doi.org/10.21873/anticanres.16255
• You have access

  5-Oxoproline Enhances 4-Hydroxytamoxifen-induced Cytotoxicity by Increasing Oxidative Stress in MCF-7 Breast Cancer Cells

  TAKANOBU NADAI, KATSUYA NARUMI, YUTO MUKAI, HINATA UEDA, AYAKO FURUGEN, YOSHITAKA SAITO and MASAKI KOBAYASHI

  Anticancer Research March 2023, 43 (3) 1113-1120; DOI: https://doi.org/10.21873/anticanres.16256
• You have access

  A Pharmacokinetic-Pharmacodynamic Model Predicts Uracil-tegafur Effect on Tumor Shrinkage and Myelosuppression in a Colorectal Cancer Rat Model

  SHINJI KOBUCHI, MOTOI TSUDA, MAKI OKAMURA, TAKANORI NAKAMURA and YUKAKO ITO

  Anticancer Research March 2023, 43 (3) 1121-1130; DOI: https://doi.org/10.21873/anticanres.16257
• You have access

  Givinostat Inhibition of Sp1-dependent MGMT Expression Sensitizes Glioma Stem Cells to Temozolomide

  YURIKA NAKAGAWA-SAITO, YUTA MITOBE, KEITA TOGASHI, SHUHEI SUZUKI, ASUKA SUGAI, CHIFUMI KITANAKA and MASASHI OKADA

  Anticancer Research March 2023, 43 (3) 1131-1138; DOI: https://doi.org/10.21873/anticanres.16258
• You have access

  Dihydroartemisinin Induced Apoptosis and Synergized With Chemotherapy in Pleural Effusion Lymphoma Cells

  PLOYPLOEN PHIKULSOD, RYUSHO KARIYA, JUTATIP PANAAMPON and SEIJI OKADA

  Anticancer Research March 2023, 43 (3) 1139-1148; DOI: https://doi.org/10.21873/anticanres.16259
• You have access

  Streptonigrin Mitigates Lung Cancer-induced Cachexia by Suppressing TCF4/TWIST1-induced PTHLH Expression

  XUE-QUAN FANG, SEONGHOON LEE, YOUNG-SEON KIM, GA EUL HAN, CHANG-HOON LIM and JI-HONG LIM

  Anticancer Research March 2023, 43 (3) 1149-1157; DOI: https://doi.org/10.21873/anticanres.16260
• You have access

  Down-regulating Effect of a Standardized Extract of Cultured Lentinula edodes mycelia on Cortactin in Prostate Cancer Cells Is Dependent on Malignant Potential

  SHIN-NOSUKE YAMASHITA, YOSHIATSU TANAKA, TAKAO KITAGAWA, BYRON BARON, KAZUHIRO TOKUDA, DURGA PAUDEL, KOJI NAKAGAWA, TOHRU OHTA, JUN-ICHI HAMADA, MASANOBU KOBAYASHI, HIROKI NAGAYASU and YASUHIRO KURAMITSU

  Anticancer Research March 2023, 43 (3) 1159-1166; DOI: https://doi.org/10.21873/anticanres.16261
• You have access

  Hinokitiol Inhibits the Viability of Oral Squamous Carcinoma Cells by Inducing Apoptosis and Autophagy

  HSIN-CHIEH LIN, CHIH-CHUN WANG, CHING-FANG WU, YUAN-HO LIN, WEI-CHANG LEE, PO-JEN CHEN, YU CHANG and YU-CHIEH SU

  Anticancer Research March 2023, 43 (3) 1167-1173; DOI: https://doi.org/10.21873/anticanres.16262
• You have access

  Artesunate Exhibits Synergy With Cisplatin and Cytotoxicity for Upper Tract and Bladder Urothelial Carcinoma Cells

  SAN-YUAN CHEN, CHUN-NUN CHAO, HSIN-YI HUANG, PEI-WEN ZHAO and CHIUNG-YAO FANG

  Anticancer Research March 2023, 43 (3) 1175-1184; DOI: https://doi.org/10.21873/anticanres.16263
• You have access

  Oncolytic Effect of a Recombinant Vesicular Stomatitis Virus Encoding a Tumor-suppressor MicroRNA in an Osteosarcoma Mouse Model

  TOMOHIKO SAKUDA, TADAHIKO KUBO, MUHAMMAD PHETRUS JOHAN, TAISUKE FURUTA, TAKEMASA SAKAGUCHI and NOBUO ADACHI

  Anticancer Research March 2023, 43 (3) 1185-1191; DOI: https://doi.org/10.21873/anticanres.16264
• You have access

  Fluoxetine Inhibits STAT3-mediated Survival and Invasion of Osteosarcoma Cells

  WEI-TING CHEN, YUAN-HSIN TSAI, PEGGY TAN, FEI-TING HSU, HUI-MIN DAVID WANG, WEI-CHIN LIN, FENG-HUEI LIN and CHING-TE WU

  Anticancer Research March 2023, 43 (3) 1193-1199; DOI: https://doi.org/10.21873/anticanres.16265
• You have access

  Anticancer Effects of Antidepressants in Hepatocellular Carcinoma Cells

  YA-HUI HUANG and CHAU-TING YEH

  Anticancer Research March 2023, 43 (3) 1201-1206; DOI: https://doi.org/10.21873/anticanres.16266
• You have access

  Redox-mediated Anticancer Activity of Anti-parasitic Drug Fenbendazole in Triple-negative Breast Cancer Cells

  SEVERINA SEMKOVA, BILIANA NIKOLOVA, IANA TSONEVA, GEORGI ANTOV, DONIKA IVANOVA, ANTON ANGELOV, ZHIVKO ZHELEV and RUMIANA BAKALOVA

  Anticancer Research March 2023, 43 (3) 1207-1212; DOI: https://doi.org/10.21873/anticanres.16267
• You have access

  Docosahexaenoic Acid Potentiates the Anticancer Effect of the Menadione/Ascorbate Redox Couple by Increasing Mitochondrial Superoxide and Accelerating ATP Depletion

  DONIKA IVANOVA, SEVERINA SEMKOVA, ZVEZDELINA YANEVA, BILIANA NIKOLOVA, ZHIVKO ZHELEV, RUMIANA BAKALOVA and ICHIO AOKI

  Anticancer Research March 2023, 43 (3) 1213-1220; DOI: https://doi.org/10.21873/anticanres.16268
• You have access

  Gene Profiling of Cannabis-sativa-mediated Apoptosis in Human Melanoma Cells

  KANITA POOMMARAPAN, PAISAL RUMMANEETHORN, ATTASIT SRISUBAT, NUNTAKAN SUWANPIDOKKUL, PETCHPAILIN LEENUTAPHONG, THAMTHIWAT NARARATWANCHAI, SIRADA SRIHIRUN, WANTHANEE PHETCHENGKAO, KANKANIT SURIYACHAN and SALUNYA TANCHAROEN

  Anticancer Research March 2023, 43 (3) 1221-1237; DOI: https://doi.org/10.21873/anticanres.16269
• You have access

  A Standardized Extract of Cultured Lentinula edodes mycelia Up-regulates COX-2 in Inflammation-related Malignant Progressive Fibrosarcoma Cell Clone QRsP-11

  TAKAO KITAGAWA, SHAJEDUL ISLAM, BYRON BARON, KAZUHIRO TOKUDA, DURGA PAUDEL, TOHRU OHTA, KOJI NAKAGAWA, MASANOBU KOBAYASHI, FUTOSHI OKADA and YASUHIRO KURAMITSU

  Anticancer Research March 2023, 43 (3) 1239-1244; DOI: https://doi.org/10.21873/anticanres.16270
• You have access

  Aurelianolides from Aureliana fasciculata var. fasciculata Trigger Apoptosis With Caspase Activation in Human Leukemia Cells

  GUSTAVO WERNECK DE SOUZA E SILVA, ANDRÉ MESQUITA MARQUES, ANA PAULA GREGÓRIO ALVES FONTÃO, SIMONE CRISTINA DE MOURA LIMA, MARIA AUXILIADORA COELHO KAPLAN, MARIA RAQUEL FIGUEIREDO and ANDRÉ LUIZ FRANCO SAMPAIO

  Anticancer Research March 2023, 43 (3) 1245-1253; DOI: https://doi.org/10.21873/anticanres.16271
• Open Access

  Efficacy of Multimodality Approach in Patients With Recurrent Head and Neck Squamous Cell Carcinoma

  PASCALE ALICIA HOELL, KHALED ELSAYAD, HENDRIK BERSSENBRUEGGE, DOMINIK HERING, CHRISTOPHER KITTEL, JOHANNES KLEINHEINZ, ANNALEN BLECKMANN, GEORG EVERS, EVA WARDELMANN, CLAUDIA RUDACK and HANS THEODOR EICH

  Anticancer Research March 2023, 43 (3) 1255-1263; DOI: https://doi.org/10.21873/anticanres.16272