Table of Contents

Clinical Studies

• Open Access

  Real-World Data on Olaparib in Relapsed BRCA-mutated Ovarian Cancer: A Multicenter GINECO RETROLA Cohort Study

  HELOÏSE BOURIEN, LEÏLA BENGRINE LEFEVRE, MARIE-ANGE MOURET-REYNIER, BERNARD ASSELAIN, BRIGITTE LUCAS, CELINE GAVOILLE, CORINA CORNILA, LAURENE GAVOILLE, EMELINE COLOMBA, ANNE PATSOURIS, MICHEL FABBRO, CAMILLE CHAKIBA, PHILIPPE TOUSSAINT, HELENE SIMON, DOMINIQUE BERTON, DELPHINE GARBAY, CLAIRE GARNIER TIXIDRE, DAVID COEFFIC, AURELIE MORVAN, OLIVIER COLLARD and THIBAULT DE LA MOTTE ROUGE

  Anticancer Research February 2023, 43 (2) 653-662; DOI: https://doi.org/10.21873/anticanres.16202
• Open Access

  Risk of Neurological Decline in Patients With Temporal Lobe Brain Masses

  JARED SWEENEY, MELANIE BONDOC, SRUTI BANDLAMURI, MATT HOLDAWAY, POUYA ENTEZAMI, MICHAEL W. O’BRIEN and MATTHEW A. ADAMO

  Anticancer Research February 2023, 43 (2) 663-668; DOI: https://doi.org/10.21873/anticanres.16203
• Open Access

  Refined Diagnosis of Pleural Effusions by Immunocytochemistry of Cell Blocks

  HIRSH KOYI and ERIK WILANDER

  Anticancer Research February 2023, 43 (2) 669-673; DOI: https://doi.org/10.21873/anticanres.16204
• Open Access

  Comparison of the Efficacy and Toxicity of Concurrent Chemoradiotherapy and Durvalumab and Concurrent Chemoradiotherapy Alone for Locally Advanced Non-small Cell Lung Cancer With N3 Lymph Node Metastasis

  TAKANORI ABE, MISAKI IINO, SATOSHI SAITO, TOMOMI AOSHIKA, YASUHIRO RYUNO, TOMOHIRO OHTA, MITSUNOBU IGARI, RYUTA HIRAI, YU KUMAZAKI, YU MIURA, KYOICHI KAIRA, HIROSHI KAGAMU, SHIN-EI NODA and SHINGO KATO

  Anticancer Research February 2023, 43 (2) 675-682; DOI: https://doi.org/10.21873/anticanres.16205
• Open Access

  Ki67 and E-cadherin Are Independent Predictors of Long-term Survival in Endometrial Carcinoma

  BELEN MARTIN-SALAMANCA, DIEGO ERASUN, JAVIER LLORCA and JOSE SCHNEIDER

  Anticancer Research February 2023, 43 (2) 683-687; DOI: https://doi.org/10.21873/anticanres.16206
• Open Access

  Clinical Course of Vitamin B12 Deficiency and Associated Risk Factors in Patients After Total Gastrectomy for Gastric Cancer

  TORU AOYAMA, KENTARO HARA, YUKIO MAEZAWA, KEISUKE KAZAMA, ITARU HASHIMOTO, SHO SAWAZAKI, KEISUKE KOMORI, HIROSHI TAMAGAWA, AYAKO TAMAGAWA, KAZUKI KANO, HARUHIKO CHO, JUNYA MORITA, KENKI SEGAMI, MIE ISHIMOTO, TAKASHI OSHIMA, NORIO YUKAWA and YASUSHI RINO

  Anticancer Research February 2023, 43 (2) 689-694; DOI: https://doi.org/10.21873/anticanres.16207
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  Preoperative Plasma miRNA Levels Predict Prognosis in Early-stage Malignant Melanoma

  MAHYAR SHARIF BAGHERI, JIRI POLIVKA, INKA TRESKOVA, KATERINA HOUFKOVA, TEREZA KNIZKOVA, VLASTIMIL WOZNICA, TOMAS FIKRLE, KRISTYNA PIVOVARCIKOVA, MARTIN SVATON, DATTATRYA SHETTI, RASHMI NEGI and MARTIN PESTA

  Anticancer Research February 2023, 43 (2) 695-706; DOI: https://doi.org/10.21873/anticanres.16208
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  Evaluation of 95-Gene Classifier of Formalin-fixed Paraffin-embedded Tissues in ER-positive, HER2-negative, and Node-negative Breast Cancer

  HIROKO YAMASHITA, KANAKO C. HATANAKA, KEISUKE YAMAGISHI, YURIA SAITO, KENGO HAMASAKI, MITSURU TANIGUCHI, ASAMI OKUMURA, AYAE NANGE, YOSHIHIRO MATSUNO and YUTAKA HATANAKA

  Anticancer Research February 2023, 43 (2) 707-711; DOI: https://doi.org/10.21873/anticanres.16209
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  Real-world Efficacy and Safety of Atezolizumab Plus Bevacizumab, Paclitaxel and Carboplatin for First-line Treatment of Japanese Patients With Metastatic Non-squamous Non-small Cell Lung Cancer

  NOBUMITSU IKEUCHI, FUMIYASU IGATA, ERIKO KINOSHITA, TOSHIAKI KAWABATA, IBUN TAN, YUSUKE OSAKI, RIKAKO OTSUKA, RINTARO ON, TAKATO IKEDA, AKIRA NAKAO, TOMOYA SASAKI, TAKASHI AOYAMA, RYOSUKE HIRANO, TAISHI HARADA, NORIYUKI EBI, MASAKI FUJITA and HIROYUKI INOUE

  Anticancer Research February 2023, 43 (2) 713-724; DOI: https://doi.org/10.21873/anticanres.16210
• Open Access

  Relationship Between Osimertinib Concentration and Clinical Response in Japanese Patients With Non-small Cell Lung Cancer

  MIZUKI YAMAZAKI, NAO KOMIZO, HIROTOSHI IIHARA, CHIEMI HIROSE, KOMEI YANASE, YUTO YAMADA, JUNKI ENDO, SHUJI YAMASHITA, YASUSHI OHNO, KENICHIRO TODOROKI, AKIO SUZUKI and HIDEKI HAYASHI

  Anticancer Research February 2023, 43 (2) 725-732; DOI: https://doi.org/10.21873/anticanres.16211
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  Breast Conserving Surgery in Combination With Targeted Intraoperative Radiotherapy Compared to Mastectomy for In-breast-tumor-recurrence

  HANS-CHRISTIAN KOLBERG, HELENA NIESING, JAYANT S. VAIDYA, LEYLA AKPOLAT-BASCI, ABDRHMAN MAGUZ, OLIVER HOFFMANN, GYOERGY LOEVEY, MILTIADES STEPHANOU and CORNELIA KOLBERG-LIEDTKE

  Anticancer Research February 2023, 43 (2) 733-739; DOI: https://doi.org/10.21873/anticanres.16212
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  Independent Validation of a Risk Stratification Model Predicting Survival in Elderly Patients Irradiated for Bone Metastases

  CARSTEN NIEDER, LUKA STANISAVLJEVIC, BÅRD MANNSÅKER and ELLINOR C. HAUKLAND

  Anticancer Research February 2023, 43 (2) 741-747; DOI: https://doi.org/10.21873/anticanres.16213
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  Prognostic Factors and Independent Validation of a Risk Stratification Model in Octogenarian Patients Irradiated for Brain Metastases

  CARSTEN NIEDER and ASTRID DALHAUG

  Anticancer Research February 2023, 43 (2) 749-753; DOI: https://doi.org/10.21873/anticanres.16214
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  Lenvatinib Versus Sorafenib in Advanced Hepatic Cell Carcinoma: A Double Center Retrospective Analysis

  GIOVANNI ANTONIO MARROCCO, MARIANNA SILLETTA, VINCENZO BIANCO, FRANCESCO MONDERA, CAROLINA SCIORTINO, LAURA PAPPALARDO, VALENTINA VIGLIALORO, ENRICO CORTESI, GIUSEPPE TONINI and SALVATORE CAPONNETTO

  Anticancer Research February 2023, 43 (2) 755-763; DOI: https://doi.org/10.21873/anticanres.16215
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  Pelvic Recurrence After Curative Resection for Rectal Adenocarcinoma: Impact of Surgery on Survival

  CECILIA FERRARI, LETIZIA CUNIOLO, MATTEO MASCHERINI, MATTEO SANTOLIQUIDO, STEFANO DI DOMENICO and FRANCO DE CIAN

  Anticancer Research February 2023, 43 (2) 765-771; DOI: https://doi.org/10.21873/anticanres.16216
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  Breaking Bad News During the COVID-19 Pandemic: A Systematic Review of the Literature

  GEORGIOS GOUMAS, NIKOLAOS SYRIGOS, ELENI FYTA, THEODOROS I. DARDAVESIS and EFFIE SIMOU

  Anticancer Research February 2023, 43 (2) 773-779; DOI: https://doi.org/10.21873/anticanres.16217
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  Correlation of Pre- and Post-radio-chemotherapy MRI Texture Features With Tumor Response in Rectal Cancer

  FABIOLA PAIAR, MICHELA GABELLONI, FRANCESCO PASQUALETTI, PAOLA COCUZZA, SABRINA MONTRONE, CHIARA ARENA, LORENZO FAGGIONI, ZENO FALASCHI, LORENZO DEL SECCO, ANGEL ALBERICH-BAYARRI, LUIS MARTI BONMATI and EMANUELE NERI

  Anticancer Research February 2023, 43 (2) 781-788; DOI: https://doi.org/10.21873/anticanres.16218
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  Small Bowel Lipomatosis: An Unusual Radiological Finding in Patients With Renal Cell Cancer on Pazopanib

  ANAND SHARMA, AMISH LAKHANI, SUBHADIP GHOSH-RAY, SALMA ALAM, ANWAR PADHANI, ANDREW GOGBASHIAN and PAUL NATHAN

  Anticancer Research February 2023, 43 (2) 789-793; DOI: https://doi.org/10.21873/anticanres.16219
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  Comparison of Two Cisplatin Regimens for Chemoradiation in Patients With Squamous-cell Carcinoma of the Head and Neck

  INGA ZWAAN, TAMER SOROR, KARL L. BRUCHHAGE, SAMER G. HAKIM, STEVEN E. SCHILD and DIRK RADES

  Anticancer Research February 2023, 43 (2) 795-800; DOI: https://doi.org/10.21873/anticanres.16220
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  Comparison of Three Survival Scores in a Series of Patients ≥80 Years of Age Irradiated for Bone Metastases

  DIRK RADES, CANSU DELIKANLI, STEVEN E. SCHILD, CHARLOTTE KRISTIANSEN, SOREN TVILSTED and STEFAN JANSSEN

  Anticancer Research February 2023, 43 (2) 801-807; DOI: https://doi.org/10.21873/anticanres.16221
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  Carbon Ion Radiotherapy Versus Perioperative Adjuvant Chemotherapy and Curative Surgery for Resectable Pancreatic Cancer

  NAOTO YAMAMOTO, TAKASHI OSHIMA, SHINNOSUKE KAWAHARA, DAISHI TAKAHASHI, YUTO KAMIOKA, MASAAKI MURAKAWA, HIROYUKI KATOH, MAKOTO UENO and SOICHIRO MORINAGA

  Anticancer Research February 2023, 43 (2) 809-815; DOI: https://doi.org/10.21873/anticanres.16222
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  Comparing Survival Outcomes and Impact of EPIC in Patients Undergoing CRS/HIPEC for Mucinous Appendiceal Neoplasm

  MELANIE MERCADO, RAPHAEL SHAMAVONIAN, ERNEST CHENG, NIMA AHMADI and DAVID L. MORRIS

  Anticancer Research February 2023, 43 (2) 817-822; DOI: https://doi.org/10.21873/anticanres.16223
• Open Access

  Evaluation of the Impact of Smoking and Alcohol Consumption on Toxicity and Outcomes of Chemoradiation for Head and Neck Cancer

  DIRK RADES, INGA ZWAAN, STEFAN JANSSEN, NATHAN Y. YU, STEVEN E. SCHILD, CHRISTIAN IDEL, RALPH PRIES, SAMER G. HAKIM and TAMER SOROR

  Anticancer Research February 2023, 43 (2) 823-830; DOI: https://doi.org/10.21873/anticanres.16224
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  Chemerin and Chemokine-like Receptor 1 Are Not Prognostic in Colorectal Carcinoma

  FLORIAN WEBER, RUDOLF JUNG, OLIVER TREECK and CHRISTA BUECHLER

  Anticancer Research February 2023, 43 (2) 831-839; DOI: https://doi.org/10.21873/anticanres.16225
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  Prognostic Value of Serum Soluble PD-L1 in Metastatic Renal Cell Carcinoma Patients Treated With Nivolumab

  NAOTO WAKITA, NOBUYUKI HINATA, YUKARI BANDO, TAKUTO HARA, TOMOAKI TERAKAWA, JUNYA FURUKAWA, YUZO NAKANO and MASATO FUJISAWA

  Anticancer Research February 2023, 43 (2) 841-847; DOI: https://doi.org/10.21873/anticanres.16226
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  Prognostic Impact of Smoking on Bevacizumab Combination Chemotherapy for Advanced Breast Cancer

  KOJI TAKADA, SHINICHIRO KASHIWAGI, NOZOMI IIMORI, RIKA KOUHASHI, AKIMICHI YABUMOTO, WATARU GOTO, YUKA ASANO, YUKIE TAUCHI, KANA OGISAWA, TAMAMI MORISAKI, MASATSUNE SHIBUTANI, HIROAKI TANAKA and KIYOSHI MAEDA

  Anticancer Research February 2023, 43 (2) 849-856; DOI: https://doi.org/10.21873/anticanres.16227
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  Clinical Relevance of Proximal Gastrectomy With Double-flap Esophagogastrostomy Reconstruction With Glycemic Profile and Postgastrectomy Syndromes

  JUN SHIBAMOTO, TAKESHI KUBOTA, KEIJI NISHIBEPPU, TAKUMA OHASHI, HIROTAKA KONISHI, ATSUSHI SHIOZAKI, HITOSHI FUJIWARA and EIGO OTSUJI

  Anticancer Research February 2023, 43 (2) 857-864; DOI: https://doi.org/10.21873/anticanres.16228
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  Time to Pain Relapse After Palliative Radiotherapy for Bone Metastasis: A Prospective Multi-institutional Study

  ANNEYUKO I. SAITO, TAKAHISA HIRAI, TATSUYA INOUE, NOBORU HOJO, SATORU KAWAI, YUI KATO, KANA ITO, MASAKO KATO, YUKIKO OZAWA, HIDENORI SHINJO, KAZUMA TODA and RYO-ICHI YOSHIMURA

  Anticancer Research February 2023, 43 (2) 865-873; DOI: https://doi.org/10.21873/anticanres.16229
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  Glasgow Prognostic Score Predicts Survival and Recurrence Pattern in Patients With Hepatocellular Carcinoma After Hepatectomy

  TAKAFUMI KUMAMOTO, KAZUHISA TAKEDA, RYUSEI MATSUYAMA, YU SAWADA, KOTA SAHARA, YASUHIRO YABUSHITA, YUKI HOMMA, JUN WATANABE, MASAKATSU NUMATA, TSUTOMU SATO, DAISUKE MORIOKA, CHIKARA KUNISAKI and ITARU ENDO

  Anticancer Research February 2023, 43 (2) 875-882; DOI: https://doi.org/10.21873/anticanres.16230
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  Analysis of Clinical Factors in Olaparib-related Anemia Using Adverse Drug Event Reporting Databases

  CHIHIRO SHIRAISHI, TOSHINORI HIRAI, TORU OGURA and TAKUYA IWAMOTO

  Anticancer Research February 2023, 43 (2) 883-891; DOI: https://doi.org/10.21873/anticanres.16231
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  Prognostic Significance of Preoperative Nutritional Assessment in Elderly Patients who Underwent Laparoscopic Gastrectomy for Stage I-III Gastric Cancer

  HIDEO UEHARA, MITSUHIKO OTA, MANABU YAMAMOTO, TOMONORI NAKANOKO, YUKI SHIN, KEIICHI SHIOKAWA, YOSHIAKI FUJIMOTO, YUICHIRO NAKASHIMA, MASAHIKO SUGIYAMA, EMI ONISHI, TOMONARI SHIMAGAKI, YOHEI MANO, KEISHI SUGIMACHI, MASARU MORITA and YASUSHI TOH

  Anticancer Research February 2023, 43 (2) 893-901; DOI: https://doi.org/10.21873/anticanres.16232
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  The Prognostic Implications of Perioperative Serum Cholesterol Levels in Patients With Gastric Cancer

  ATSUSHI YAMAMOTO, KATSUTOSHI SHODA, YOSHIHIKO KAWAGUCHI, HIDENORI AKAIKE, SHINJI FURUYA, KENSUKE SHIRAISHI, KAZUYOSHI HIRAYAMA, RYO SAITO, NAOKI ASHIZAWA, KOICHI TAKIGUCHI, NAOHIRO HOSOMURA, HIDETAKE AMEMIYA, HIROMICHI KAWAIDA, HIROSHI KONO and DAISUKE ICHIKAWA

  Anticancer Research February 2023, 43 (2) 903-909; DOI: https://doi.org/10.21873/anticanres.16233
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  Outcomes of the Sequential Treatment of Unresectable Hepatocellular Carcinoma Using Lenvatinib

  DAISUKE NAKAGAWA, SHOHEI KOMATSU, YOSHIHIKO YANO, MASAHIRO KIDO, KAORI KURAMITSU, ATSUSHI YAMAMOTO, SATOSHI OMIYA, YUHI SHIMURA, TADAHIRO GOTO, HIROAKI YANAGIMOTO, HIROCHIKA TOYAMA, YOSHIHIDE UEDA, YUZO KODAMA and TAKUMI FUKUMOTO

  Anticancer Research February 2023, 43 (2) 911-918; DOI: https://doi.org/10.21873/anticanres.16234
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  Real-world Data on the Incidence of Coronavirus Disease (COVID-19) in Patients With Advanced Thoracic Cancer During the Early Phase of the Pandemic in Japan

  AKITO FUKUDA, TATSUYA YOSHIDA, SHIGEHIRO YAGISHITA, MIKA SHIOTSUKA, OSAMU KOBAYASHI, SATOSHI IWATA, HITOMI UMEGUCHI, MASATOSHI YANAGIDA, YASUHIRO IRINO, KEN MASUDA, YUKI SHINNO, YUSUKE OKUMA, YASUSHI GOTO, HIDEHITO HORINOUCHI, AKINOBU HAMADA, NOBORU YAMAMOTO and YUICHIRO OHE

  Anticancer Research February 2023, 43 (2) 919-926; DOI: https://doi.org/10.21873/anticanres.16235
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  Examining the Efficacy of Nivolumab for Gastric Cancer Focusing on Using an Inflammation-based Prognostic Score: A Multicenter Retrospective Study

  NOBUHIRO NAKAZAWA, MAKOTO SOHDA, KOHEI TATENO, TAKAYOSHI WATANABE, AKIHARU KIMURA, NORIMICHI KOGURE, HISASHI HOSAKA, ATSUSHI NAGANUMA, MASANORI SEKIGUCHI, KANA SAITO, KYOICHI OGATA, AKIHIKO SANO, MAKOTO SAKAI, HIROOMI OGAWA, KEN SHIRABE and HIROSHI SAEKI

  Anticancer Research February 2023, 43 (2) 927-934; DOI: https://doi.org/10.21873/anticanres.16236
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  Cumulative Incidence of Thromboembolism and Prognostic Impact of Stroke in BRAF V600E-mutant Non-small-cell Lung Cancer

  SHO YAMADA, AKIMASA SEKINE, ERI HAGIWARA, YOKO ONODERA, ERINA TABATA, SATOSHI IKEDA, HIDEYA KITAMURA, TOMOHISA BABA, SHIGERU KOMATSU and TAKASHI OGURA

  Anticancer Research February 2023, 43 (2) 935-938; DOI: https://doi.org/10.21873/anticanres.16237
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  Clear-cell Variant of Mucoepidermoid Carcinoma Presenting as a Palatal Mass in a 10-Year-old Boy

  SOPHIA H. HAN, THOMAS R. O’TOOLE, REID G. MEYER, KATHERINE B. GEIERSBACH, MOHAMMED N. ISLAM, LIRONG CHENG and JINPING LAI

  Anticancer Research February 2023, 43 (2) 939-942; DOI: https://doi.org/10.21873/anticanres.16238
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  Conversion Surgery After Atezolizumab Plus Bevacizumab for Primary and Peritoneal Metastasis After Hepatocellular Carcinoma Rupture

  TATSUNORI MIYATA, KAZUHIRO SUGI, TAICHI HORINO, ASUKA ONO, YOSHIYUKI TAGAYASU, DAICHI NOMOTO, MITSUHIRO INOUE, TAKAO MIZUMOTO, TATSUO KUBOTA, ERIKO YANAGIDA, TOSHIHIKO MURAYAMA, NOBUTOMO MIYANARI and HIDEO BABA

  Anticancer Research February 2023, 43 (2) 943-947; DOI: https://doi.org/10.21873/anticanres.16239