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Research ArticleClinical Studies

The Efficacy and Safety of a Low Relative Dose Intensity of Cabazitaxel in Patients With Metastatic Castration-resistant Prostate Cancer

FUMIHIKO URABE, DAIGO KOBAYASHI, KOSUKE IWATANI, YU IMAI, HAJIME ONUMA, KOICHI AIKAWA, TAKAFUMI YANAGISAWA, KOJIRO TASHIRO, HIROSHI SASAKI, JUN MIKI, KENTA MIKI and TAKAHIRO KIMURA
Anticancer Research October 2023, 43 (10) 4611-4617; DOI: https://doi.org/10.21873/anticanres.16655
FUMIHIKO URABE
1Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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DAIGO KOBAYASHI
1Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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KOSUKE IWATANI
1Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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YU IMAI
1Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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HAJIME ONUMA
1Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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KOICHI AIKAWA
1Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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TAKAFUMI YANAGISAWA
1Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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KOJIRO TASHIRO
1Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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HIROSHI SASAKI
1Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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JUN MIKI
1Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
2Department of Urology, The Jikei University School of Medicine, Kashiwa Hospital, Chiba, Japan
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KENTA MIKI
1Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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TAKAHIRO KIMURA
1Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
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  • For correspondence: tkimura{at}jikei.ac.jp
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Article Information

vol. 43 no. 10 4611-4617
DOI 
https://doi.org/10.21873/anticanres.16655
PMID 
37772549

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received July 5, 2023
  • Revision received July 27, 2023
  • Accepted July 28, 2023
  • Published online September 29, 2023.

Copyright & Usage 
Copyright © 2023 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. FUMIHIKO URABE1,#,
  2. DAIGO KOBAYASHI1,#,
  3. KOSUKE IWATANI1,
  4. YU IMAI1,
  5. HAJIME ONUMA1,
  6. KOICHI AIKAWA1,
  7. TAKAFUMI YANAGISAWA1,
  8. KOJIRO TASHIRO1,
  9. HIROSHI SASAKI1,
  10. JUN MIKI1,2,
  11. KENTA MIKI1 and
  12. TAKAHIRO KIMURA1⇑
  1. 1Department of Urology, The Jikei University School of Medicine, Tokyo, Japan;
  2. 2Department of Urology, The Jikei University School of Medicine, Kashiwa Hospital, Chiba, Japan
  1. Correspondence to: Takahiro Kimura, Department of Urology, The Jikei University School of Medicine, 3-25-8 Nishi-Shimbashi, Minato-ku, Tokyo, Japan. Tel: +81 0334331111, Fax: +81 0354001387, e-mail: tkimura{at}jikei.ac.jp
  1. ↵# These Authors contributed equally to this study.

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Anticancer Research: 43 (10)
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The Efficacy and Safety of a Low Relative Dose Intensity of Cabazitaxel in Patients With Metastatic Castration-resistant Prostate Cancer
FUMIHIKO URABE, DAIGO KOBAYASHI, KOSUKE IWATANI, YU IMAI, HAJIME ONUMA, KOICHI AIKAWA, TAKAFUMI YANAGISAWA, KOJIRO TASHIRO, HIROSHI SASAKI, JUN MIKI, KENTA MIKI, TAKAHIRO KIMURA
Anticancer Research Oct 2023, 43 (10) 4611-4617; DOI: 10.21873/anticanres.16655

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The Efficacy and Safety of a Low Relative Dose Intensity of Cabazitaxel in Patients With Metastatic Castration-resistant Prostate Cancer
FUMIHIKO URABE, DAIGO KOBAYASHI, KOSUKE IWATANI, YU IMAI, HAJIME ONUMA, KOICHI AIKAWA, TAKAFUMI YANAGISAWA, KOJIRO TASHIRO, HIROSHI SASAKI, JUN MIKI, KENTA MIKI, TAKAHIRO KIMURA
Anticancer Research Oct 2023, 43 (10) 4611-4617; DOI: 10.21873/anticanres.16655
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  • Risk Factors and Clinical Significance of Grade >=3 Neutropenia During the First Cycle of Cabazitaxel Therapy With Primary Pegfilgrastim Prophylaxis in Metastatic Castration-resistant Prostate Cancer
  • Patients Diagnosed With Metastatic Castration-sensitive Prostate Cancer and High Serum Lactate Dehydrogenase Levels Did Not Receive an Adequate Dose of Cabazitaxel
  • Impact of Novel Agents on Patient Characteristics, Treatment Patterns, and Outcomes in Patients With Metastatic Castration-resistant Prostate Cancer
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Keywords

  • Metastatic castration-resistant prostate cancer
  • cabazitaxel
  • relative dose intensity
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