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Research ArticleExperimental Studies

An MGMT Allelic Variant Can Affect Biochemical Relapse in Prostate Cancer Patients

HECTOR HUGO FURINI, KEVIN SANTIAGO DE SOUZA QUENZO FUKUSHIMA, MONYSE DE NÓBREGA, MARILESIA FERREIRA DE SOUZA, MILENE ROLDÃO SOUZA RODRIGUES, BEATRIZ BOCATTE DE MATTOS, ROBERTA LOSI GUEMBAROVSKI, PAULO EMÍLIO FUGANTI, ANDREA NAME COLADO SIMÃO, TAMIRES FLAUZINO and ILCE MARA DE SYLLOS CÓLUS
Anticancer Research January 2023, 43 (1) 369-379; DOI: https://doi.org/10.21873/anticanres.16172
HECTOR HUGO FURINI
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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KEVIN SANTIAGO DE SOUZA QUENZO FUKUSHIMA
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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MONYSE DE NÓBREGA
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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MARILESIA FERREIRA DE SOUZA
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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MILENE ROLDÃO SOUZA RODRIGUES
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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BEATRIZ BOCATTE DE MATTOS
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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ROBERTA LOSI GUEMBAROVSKI
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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PAULO EMÍLIO FUGANTI
2Hospital do Câncer de Londrina, Paraná, Brazil;
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ANDREA NAME COLADO SIMÃO
3Laboratório de Pesquisa em Imunologia Aplicada, Departamento de Patologia, Análises Clínicas e Toxicológicas, Universidade Estadual de Londrina, Paraná, Brazil
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TAMIRES FLAUZINO
3Laboratório de Pesquisa em Imunologia Aplicada, Departamento de Patologia, Análises Clínicas e Toxicológicas, Universidade Estadual de Londrina, Paraná, Brazil
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ILCE MARA DE SYLLOS CÓLUS
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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  • For correspondence: ilcecolus{at}gmail.com
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    Figure 1.

    Kaplan-Meier survival analysis. Follow-up of patients diagnosed and treated for prostate cancer (PCa), distinguished by their genotype of rs2308321 (MGMT).

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Anticancer Research: 43 (1)
Anticancer Research
Vol. 43, Issue 1
January 2023
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An MGMT Allelic Variant Can Affect Biochemical Relapse in Prostate Cancer Patients
HECTOR HUGO FURINI, KEVIN SANTIAGO DE SOUZA QUENZO FUKUSHIMA, MONYSE DE NÓBREGA, MARILESIA FERREIRA DE SOUZA, MILENE ROLDÃO SOUZA RODRIGUES, BEATRIZ BOCATTE DE MATTOS, ROBERTA LOSI GUEMBAROVSKI, PAULO EMÍLIO FUGANTI, ANDREA NAME COLADO SIMÃO, TAMIRES FLAUZINO, ILCE MARA DE SYLLOS CÓLUS
Anticancer Research Jan 2023, 43 (1) 369-379; DOI: 10.21873/anticanres.16172

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An MGMT Allelic Variant Can Affect Biochemical Relapse in Prostate Cancer Patients
HECTOR HUGO FURINI, KEVIN SANTIAGO DE SOUZA QUENZO FUKUSHIMA, MONYSE DE NÓBREGA, MARILESIA FERREIRA DE SOUZA, MILENE ROLDÃO SOUZA RODRIGUES, BEATRIZ BOCATTE DE MATTOS, ROBERTA LOSI GUEMBAROVSKI, PAULO EMÍLIO FUGANTI, ANDREA NAME COLADO SIMÃO, TAMIRES FLAUZINO, ILCE MARA DE SYLLOS CÓLUS
Anticancer Research Jan 2023, 43 (1) 369-379; DOI: 10.21873/anticanres.16172
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Keywords

  • MGMT
  • follow-up
  • SNP
  • PSA
  • recurrence
  • Prostate cancer
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