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Research ArticleExperimental Studies

An MGMT Allelic Variant Can Affect Biochemical Relapse in Prostate Cancer Patients

HECTOR HUGO FURINI, KEVIN SANTIAGO DE SOUZA QUENZO FUKUSHIMA, MONYSE DE NÓBREGA, MARILESIA FERREIRA DE SOUZA, MILENE ROLDÃO SOUZA RODRIGUES, BEATRIZ BOCATTE DE MATTOS, ROBERTA LOSI GUEMBAROVSKI, PAULO EMÍLIO FUGANTI, ANDREA NAME COLADO SIMÃO, TAMIRES FLAUZINO and ILCE MARA DE SYLLOS CÓLUS
Anticancer Research January 2023, 43 (1) 369-379; DOI: https://doi.org/10.21873/anticanres.16172
HECTOR HUGO FURINI
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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KEVIN SANTIAGO DE SOUZA QUENZO FUKUSHIMA
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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MONYSE DE NÓBREGA
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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MARILESIA FERREIRA DE SOUZA
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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MILENE ROLDÃO SOUZA RODRIGUES
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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BEATRIZ BOCATTE DE MATTOS
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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ROBERTA LOSI GUEMBAROVSKI
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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PAULO EMÍLIO FUGANTI
2Hospital do Câncer de Londrina, Paraná, Brazil;
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ANDREA NAME COLADO SIMÃO
3Laboratório de Pesquisa em Imunologia Aplicada, Departamento de Patologia, Análises Clínicas e Toxicológicas, Universidade Estadual de Londrina, Paraná, Brazil
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TAMIRES FLAUZINO
3Laboratório de Pesquisa em Imunologia Aplicada, Departamento de Patologia, Análises Clínicas e Toxicológicas, Universidade Estadual de Londrina, Paraná, Brazil
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ILCE MARA DE SYLLOS CÓLUS
1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
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  • For correspondence: ilcecolus{at}gmail.com
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Article Information

vol. 43 no. 1 369-379
DOI 
https://doi.org/10.21873/anticanres.16172
PMID 
36585213

Published By 
International Institute of Anticancer Research
Print ISSN 
0250-7005
Online ISSN 
1791-7530
History 
  • Received October 14, 2022
  • Revision received October 27, 2022
  • Accepted October 31, 2022
  • Published online December 30, 2022.

Copyright & Usage 
Copyright © 2023 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Author Information

  1. HECTOR HUGO FURINI1,
  2. KEVIN SANTIAGO DE SOUZA QUENZO FUKUSHIMA1,
  3. MONYSE DE NÓBREGA1,
  4. MARILESIA FERREIRA DE SOUZA1,
  5. MILENE ROLDÃO SOUZA RODRIGUES1,
  6. BEATRIZ BOCATTE DE MATTOS1,
  7. ROBERTA LOSI GUEMBAROVSKI1,
  8. PAULO EMÍLIO FUGANTI2,
  9. ANDREA NAME COLADO SIMÃO3,
  10. TAMIRES FLAUZINO3 and
  11. ILCE MARA DE SYLLOS CÓLUS1⇑
  1. 1Laboratório de Mutagênese e Oncogenética, Departamento de Biologia Geral, Universidade Estadual de Londrina, Paraná, Brazil;
  2. 2Hospital do Câncer de Londrina, Paraná, Brazil;
  3. 3Laboratório de Pesquisa em Imunologia Aplicada, Departamento de Patologia, Análises Clínicas e Toxicológicas, Universidade Estadual de Londrina, Paraná, Brazil
  1. Correspondence to: Ilce Mara de Syllos Cólus, Departamento de Biologia Geral, Centro de Ciências Biológicas, Universidade Estadual de Londrina, Rodovia Celso Garcia Cid, Km 380, CEP 86057-970, Londrina, Paraná, Brazil. Tel.: +55 4333715149, e-mail: ilcecolus{at}gmail.com
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An MGMT Allelic Variant Can Affect Biochemical Relapse in Prostate Cancer Patients
HECTOR HUGO FURINI, KEVIN SANTIAGO DE SOUZA QUENZO FUKUSHIMA, MONYSE DE NÓBREGA, MARILESIA FERREIRA DE SOUZA, MILENE ROLDÃO SOUZA RODRIGUES, BEATRIZ BOCATTE DE MATTOS, ROBERTA LOSI GUEMBAROVSKI, PAULO EMÍLIO FUGANTI, ANDREA NAME COLADO SIMÃO, TAMIRES FLAUZINO, ILCE MARA DE SYLLOS CÓLUS
Anticancer Research Jan 2023, 43 (1) 369-379; DOI: 10.21873/anticanres.16172

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An MGMT Allelic Variant Can Affect Biochemical Relapse in Prostate Cancer Patients
HECTOR HUGO FURINI, KEVIN SANTIAGO DE SOUZA QUENZO FUKUSHIMA, MONYSE DE NÓBREGA, MARILESIA FERREIRA DE SOUZA, MILENE ROLDÃO SOUZA RODRIGUES, BEATRIZ BOCATTE DE MATTOS, ROBERTA LOSI GUEMBAROVSKI, PAULO EMÍLIO FUGANTI, ANDREA NAME COLADO SIMÃO, TAMIRES FLAUZINO, ILCE MARA DE SYLLOS CÓLUS
Anticancer Research Jan 2023, 43 (1) 369-379; DOI: 10.21873/anticanres.16172
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Keywords

  • MGMT
  • follow-up
  • SNP
  • PSA
  • recurrence
  • Prostate cancer
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