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Research ArticleClinical Studies

Evaluation of Lung and Liver Tumor Dose Coverage Treated With the CyberKnife Synchrony System With Consideration of Measured Tracking Errors

YUICHI AKINO, HIROYA SHIOMI, NAOICHI HIGASHINAKA, TOMOHIRO KOUNO, NOBUHISA MABUCHI, FUMIAKI ISOHASHI, YUJI SEO, KEI FUJIWARA, SETSUO TAMENAGA and KAZUHIKO OGAWA
Anticancer Research January 2023, 43 (1) 231-238; DOI: https://doi.org/10.21873/anticanres.16154
YUICHI AKINO
1Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Japan;
2Soseikai CyberKnife Center, Kyoto, Japan;
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  • For correspondence: akino@radonc.med.osaka-u.ac.jp
HIROYA SHIOMI
1Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Japan;
2Soseikai CyberKnife Center, Kyoto, Japan;
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NAOICHI HIGASHINAKA
2Soseikai CyberKnife Center, Kyoto, Japan;
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TOMOHIRO KOUNO
3Osaka Breast Clinic, Osaka, Japan;
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NOBUHISA MABUCHI
2Soseikai CyberKnife Center, Kyoto, Japan;
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FUMIAKI ISOHASHI
1Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Japan;
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YUJI SEO
4Department of Carbon Ion Radiotherapy, Osaka University Graduate School of Medicine, Suita, Japan
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KEI FUJIWARA
1Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Japan;
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SETSUO TAMENAGA
1Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Japan;
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KAZUHIKO OGAWA
1Department of Radiation Oncology, Osaka University Graduate School of Medicine, Suita, Japan;
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Abstract

Background/Aim: Lung and liver tumor dose coverage was evaluated for the CyberKnife synchrony respiratory tracking system (SRTS) with consideration of the motion tracking accuracy measured for motion patterns of individual patients. Patients and Methods: Seven treatment plans of six cases treated with the SRTS were evaluated. The motion phantom was moved with the motion data derived from the treatment log files. A laser emitted from the linac head to the moving phantom block was recorded with a webcam, and the tracking accuracy was evaluated. The dose volume histogram (DVH) of planning target volume (PTV) and gross tumor volume (GTV) were calculated by a pencil beam algorithm with shifting the beams with Gaussian random numbers mimicking the measured tracking errors. Results: The tracking errors measured with the motion phantom in the lateral direction were within ±2 mm for 90% of beam-on time. The tracking errors in the longitudinal direction were within ±3.0 mm and ±1.1 mm for 90% and 50% of beam-on time, respectively. Although one case showed a decrease in the dose covering 95% of PTV (D95%) by 1.8%, the change in the dose covering 99% of GTV (D99%) was within 1%. Conclusion: This study evaluated the motion tracking errors of the SRTS by a motion phantom moved with the patients’ respiration signal, and the impact of the tracking errors on the target coverage was calculated. Even for respiratory patterns with large maximum tracking errors, sufficient GTV coverage is achievable if the beam is accurately delivered for high percentage of beam-on time.

Key Words:
  • CyberKnife
  • synchrony
  • motion tracking accuracy
  • DVH
  • Received November 16, 2022.
  • Revision received November 29, 2022.
  • Accepted November 30, 2022.
  • Copyright © 2023 International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.
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Anticancer Research: 43 (1)
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Evaluation of Lung and Liver Tumor Dose Coverage Treated With the CyberKnife Synchrony System With Consideration of Measured Tracking Errors
YUICHI AKINO, HIROYA SHIOMI, NAOICHI HIGASHINAKA, TOMOHIRO KOUNO, NOBUHISA MABUCHI, FUMIAKI ISOHASHI, YUJI SEO, KEI FUJIWARA, SETSUO TAMENAGA, KAZUHIKO OGAWA
Anticancer Research Jan 2023, 43 (1) 231-238; DOI: 10.21873/anticanres.16154

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Evaluation of Lung and Liver Tumor Dose Coverage Treated With the CyberKnife Synchrony System With Consideration of Measured Tracking Errors
YUICHI AKINO, HIROYA SHIOMI, NAOICHI HIGASHINAKA, TOMOHIRO KOUNO, NOBUHISA MABUCHI, FUMIAKI ISOHASHI, YUJI SEO, KEI FUJIWARA, SETSUO TAMENAGA, KAZUHIKO OGAWA
Anticancer Research Jan 2023, 43 (1) 231-238; DOI: 10.21873/anticanres.16154
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Keywords

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